Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Muhammad K. Mirza"'
Autor:
Asrar B. Malik, You Yang Zhao, Jun Yuan, Xiao Pei Gao, Muhammad K. Mirza, Viktor Brovkovych, Sean Garrean, Chinnaswamy Tiruppathi
Publikováno v:
The American Journal of Pathology. 176:2344-2351
Caveolin-1 (Cav1), the scaffolding protein of caveolae, has been shown to play an important role in host defense and inflammation. However, the underlying molecular basis for these actions remains elusive. Here, using double mutant mice with genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3e24b639a2d9b368dce65414854891
https://doi.org/10.2353/ajpath.2010.091088
https://doi.org/10.2353/ajpath.2010.091088
Autor:
Ramaswamy Ramchandran, Panos Kouklis, Muhammad K. Mirza, Stephen M. Vogel, Asrar B. Malik, Dolly Mehta
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 295:L363-L369
Activation of the Rho GTPase Cdc42 has been shown in endothelial cell monolayers to prevent disassembly of interendothelial junctions and the increase in endothelial permeability. Here, we addressed the in vivo role of Cdc42 activity in mediating end
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe1fffafe65364f7e51375503514071
https://doi.org/10.1152/ajplung.90241.2008
https://doi.org/10.1152/ajplung.90241.2008
Autor:
Vladimir V. Kalinichenko, Muhammad K. Mirza, Yidan D. Zhao, I-Ching Wang, Robert H. Costa, You Yang Zhao, Asrar B. Malik, Xiaopei Gao, Randall S. Frey
Publikováno v:
Journal of Clinical Investigation. 116:2333-2343
Recovery of endothelial integrity after vascular injury is vital for endothelial barrier function and vascular homeostasis. However, little is known about the molecular mechanisms of endothelial barrier repair following injury. To investigate the fun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96830c5220615712c2e02ee5514c077e
https://doi.org/10.1172/jci27154
https://doi.org/10.1172/jci27154
Autor:
Fan Yi, Muhammad K. Mirza, Yidan D. Zhao, Xiaojia Huang, Lei Cai, Zhiyu Dai, Stephen M. Vogel, You Yang Zhao, Jingsong Xu
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 306(6)
Excessive reactive oxygen/nitrogen species have been associated with the onset, progression, and outcome of sepsis, both in preclinical and clinical studies. However, the signaling pathways regulating oxidative/nitrative stress in the pathogenesis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e171e691230b93dc47bacc2d5868e5
https://pubmed.ncbi.nlm.nih.gov/24441873
https://pubmed.ncbi.nlm.nih.gov/24441873
Autor:
You Yang Zhao, Muhammad K. Mirza, Dave L. Geenen, Jason X.-J. Yuan, Franz Hofmann, Xiaojia Huang, Lei Cai, Yidan D. Zhao
Publikováno v:
The American journal of pathology. 180(6)
Protein kinase G (PKG) plays an important role in the regulation of vascular smooth cell contractility and is a critical mediator of nitric oxide signaling, which regulates cardiovascular homeostasis. PKG-I-knockout (Prkg1(-/-)) mice exhibit impaired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e1eb8f153ef305f71062cea39ed653
https://pubmed.ncbi.nlm.nih.gov/22632818
https://pubmed.ncbi.nlm.nih.gov/22632818
Autor:
You Yang Zhao, Randall S. Frey, Asrar B. Malik, Yidan D. Zhao, Ying Sun, Muhammad K. Mirza, Steven M. Vogel
Publikováno v:
A17. MECHANISMS OF ACUTE LUNG INJURY: ROLE OF ENDOTHELIUM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::975266aef9180bb338b54ee04fe5408b
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a1036
https://doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a1036
Autor:
Hari Hara Potula, John Wharton, You Yang Zhao, Julia H. Huang, Asrar B. Malik, Jason X.-J. Yuan, Viktor Brovkovych, Yidan D. Zhao, Muhammad K. Mirza, Steven M. Vogel
Pulmonary hypertension (PH) is an unremitting disease defined by a progressive increase in pulmonary vascular resistance leading to right-sided heart failure. Using mice with genetic deletions of caveolin 1 (Cav1) and eNOS (Nos3), we demonstrate here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e81aab278edd913d5daa9b163374ce30
https://europepmc.org/articles/PMC2701851/
https://europepmc.org/articles/PMC2701851/
Autor:
Ying Sun, You Yang Zhao, Randall S. Frey, Muhammad K. Mirza, Yidan D. Zhao, Hari Hara Potula, Asrar B. Malik, Steven M. Vogel
Publikováno v:
The Journal of Experimental Medicine
Repair of the injured vascular intima requires a series of coordinated events that mediate both endothelial regeneration and reannealing of adherens junctions (AJs) to form a restrictive endothelial barrier. The forkhead transcription factor FoxM1 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c8ce3ab76e7d8753c7cc23b756bf422
https://doi.org/10.1083/jcb1903oia6
https://doi.org/10.1083/jcb1903oia6