Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Muhammad Imtiaz, Ashraf"'
1
Akademický článek
Sex-specific molecular signature of mouse podocytes in homeostasis and in response to pharmacological challenge with rapamycin
Autor: Ola Al-Diab, Christin Sünkel, Eric Blanc, Rusan Ali Catar, Muhammad Imtiaz Ashraf, Hongfan Zhao, Pinchao Wang, Markus M. Rinschen, Raphaela Fritsche-Guenther, Florian Grahammer, Sebastian Bachmann, Dieter Beule, Jennifer A. Kirwan, Nikolaus Rajewsky, Tobias B. Huber, Dennis Gürgen, Angelika Kusch
Publikováno v: Biology of Sex Differences, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Background Sex differences exist in the prevalence and progression of major glomerular diseases. Podocytes are the essential cell-type in the kidney which maintain the physiological blood-urine barrier, and pathological changes in podocyte h
Externí odkaz: https://doaj.org/article/6486c593796f4fa4bf8ff685f8544f3b
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2
Akademický článek
Depletion of donor dendritic cells ameliorates immunogenicity of both skin and hind limb transplants
Autor: Muhammad Imtiaz Ashraf, Joerg Mengwasser, Anja Reutzel-Selke, Dietrich Polenz, Kirsten Führer, Steffen Lippert, Peter Tang, Edward Michaelis, Rusan Catar, Johann Pratschke, Christian Witzel, Igor M. Sauer, Stefan G. Tullius, Barbara Kern
Publikováno v: Frontiers in Immunology, Vol 15 (2024)
Acute cellular rejection remains a significant obstacle affecting successful outcomes of organ transplantation including vascularized composite tissue allografts (VCA). Donor antigen presenting cells (APCs), particularly dendritic cells (DCs), orches
Externí odkaz: https://doaj.org/article/cb6068b1a8d7413cbf4de018498537e7
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3
Akademický článek
The Role of NOX2-Derived Reactive Oxygen Species in the Induction of Endothelin-Converting Enzyme-1 by Angiotensin II
Autor: Michael Adu-Gyamfi, Claudia Goettsch, Julian Kamhieh-Milz, Lei Chen, Anna Maria Pfefferkorn, Anja Hofmann, Coy Brunssen, Gregor Müller, Thomas Walther, Muhammad Imtiaz Ashraf, Henning Morawietz, Janusz Witowski, Rusan Catar
Publikováno v: Antioxidants, Vol 13, Iss 4, p 500 (2024)
Endothelin-1 is a key regulator of vascular tone and blood pressure in health and disease. We have recently found that ET-1 production in human microvascular endothelial cells (HMECs) can be promoted by angiotensin II (Ang II) through a novel mechani
Externí odkaz: https://doaj.org/article/93e54855a4cf439a8fdd4396e9578845
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4
Akademický článek
Moderate LMWH Anticoagulation Improves Success Rate of Hind Limb Allotransplantation in Mice
Autor: Barbara Kern, MD, Muhammad-Imtiaz Ashraf, PhD, Anja Reutzel-Selke, PhD, Joerg Mengwasser, PhD, Dietrich Polenz, Edward Michaelis, MD, Johann Pratschke, MD, PhD, Stefan G. Tullius, MD, PhD, Christian Witzel, MD, PhD, Igor M. Sauer, MD, PhD
Publikováno v: Plastic and Reconstructive Surgery, Global Open, Vol 11, Iss 9, p e5249 (2023)
Background:. The mouse hind limb model represents a powerful research tool in vascularized composite tissue allotransplantation, but its applicability is limited due to poor graft survival (62%–83%). Vascular thrombosis and massive hemorrhage are t
Externí odkaz: https://doaj.org/article/098561d647b643bf92f5c1972a95c797
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5
Akademický článek
Expanded Hemodialysis ameliorates uremia-induced impairment of vasculoprotective KLF2 and concomitant proinflammatory priming of endothelial cells through an ERK/AP1/cFOS-dependent mechanism
Autor: Hongfan Zhao, Dashan Wu, Michael Adu Gyamfi, Pinchao Wang, Christian Luecht, Anna Maria Pfefferkorn, Muhammad Imtiaz Ashraf, Julian Kamhieh-Milz, Janusz Witowski, Duska Dragun, Klemens Budde, Ralf Schindler, Daniel Zickler, Guido Moll, Rusan Catar
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
AimsExpanded hemodialysis (HDx) therapy with improved molecular cut-off dialyzers exerts beneficial effects on lowering uremia-associated chronic systemic microinflammation, a driver of endothelial dysfunction and cardiovascular disease (CVD) in hemo
Externí odkaz: https://doaj.org/article/eb3a57d09178403b87ad5ee78122776d
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7
Akademický článek
Natural Killer Cells Promote Kidney Graft Rejection Independently of Cyclosporine A Therapy
Autor: Muhammad Imtiaz Ashraf, Attia Sarwar, Anja A. Kühl, Elena Hunger, Arne Sattler, Felix Aigner, Heinz Regele, Martina Sauter, Karin Klingel, Stefan Schneeberger, Thomas Resch, Katja Kotsch
Publikováno v: Frontiers in Immunology, Vol 10 (2019)
Natural Killer (NK) cells have recently been recognized as key players in antibody-mediated chronic allograft failure, thus requiring a comprehensive understanding whether NK cells can escape conventional immunosuppressive regimens. Influence of cycl
Externí odkaz: https://doaj.org/article/a703badcb7a54b60836c475e9cc750a4
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9
Akademický článek
Prediction of delayed graft function and long-term graft survival by serum and urinary neutrophil gelatinase-associated lipocalin during the early postoperative phase after kidney transplantation.
Autor: Herbert Thomas Maier, Muhammad Imtiaz Ashraf, Christian Denecke, Sascha Weiss, Florian Augustin, Franka Messner, Natalie Vallant, Matthias Böcklein, Christian Margreiter, Georg Göbel, Johann Pratschke, Dietmar Öfner-Velano, Felix Aigner
Publikováno v: PLoS ONE, Vol 13, Iss 1, p e0189932 (2018)
Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as an early marker protein for kidney dysfunction in various clinical settings. In this prospective study we evaluated serial changes of serum and urinary NGAL within the first 7 days afte
Externí odkaz: https://doaj.org/article/a5cf168dcf5d4cad8c25bec6ca3d90f7
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