Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Muhammad El-Shafeey"'
Autor:
Kathleen Pappritz, Sarah-Lena Puhl, Isabel Matz, Erik Brauer, Yi Xuan Shia, Muhammad El-Shafeey, Suzanne E. Koch, Kapka Miteva, Christin Mucha, Georg N. Duda, Ansgar Petersen, Sabine Steffens, Carsten Tschöpe, Sophie Van Linthout
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundAge and sex are prominent risk factors for heart failure and determinants of structural and functional changes of the heart. Cardiac fibroblasts (cFB) are beyond their task as extracellular matrix-producing cells further recognized as infla
Externí odkaz:
https://doaj.org/article/431c58d3a3d04068a86c2900a66337bc
Autor:
Kathleen Pappritz, Jie Lin, Muhammad El‐Shafeey, Henry Fechner, Uwe Kühl, Alessio Alogna, Frank Spillmann, Ahmed Elsanhoury, Rainer Schulz, Carsten Tschöpe, Sophie Van Linthout
Publikováno v:
ESC Heart Failure, Vol 9, Iss 2, Pp 925-941 (2022)
Abstract Aim The acute phase of a coxsackievirus 3 (CVB3)‐induced myocarditis involves direct toxic cardiac effects and the systemic activation of the immune system, including the cardiosplenic axis. Consequently, the nucleotide‐binding oligomeri
Externí odkaz:
https://doaj.org/article/a2758d127c774136b0ea4616cf588917
Autor:
Kathleen Pappritz, Fengquan Dong, Kapka Miteva, Arpad Kovacs, Muhammad El-Shafeey, Bahtiyar Kerim, Lisa O'Flynn, Stephen Joseph Elliman, Timothy O'Brien, Nazha Hamdani, Carsten Tschöpe, Sophie Van Linthout
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Mesenchymal stromal cells (MSCs) are an attractive cell type for cell therapy given their immunomodulatory, anti-fibrotic, and endothelial-protective features. The heparin sulfate proteoglycan, syndecan-2/CD362, has been identified as a f
Externí odkaz:
https://doaj.org/article/1bf03731b8664f09bd7aaa83b3413463
Autor:
Kapka Miteva, Kathleen Pappritz, Marzena Sosnowski, Muhammad El-Shafeey, Irene Müller, Fengquan Dong, Konstantinos Savvatis, Jochen Ringe, Carsten Tschöpe, Sophie Van Linthout
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Abstract Inflammation in myocarditis induces cardiac injury and triggers disease progression to heart failure. NLRP3 inflammasome activation is a newly identified amplifying step in the pathogenesis of myocarditis. We previously have demonstrated tha
Externí odkaz:
https://doaj.org/article/442a663e3c974fe49b0cc01f3dc78019
Autor:
M. A. Abu-Saied, Mohamed Elnouby, Tarek Taha, Muhammad El-shafeey, Ali G. Alshehri, Saad Alamri, Huda Alghamdi, Ali Shati, Sulaiman Alrumman, Mohamed Al-Kahtani, Mahmoud Moustafa
Publikováno v:
Molecules, Vol 25, Iss 8, p 1936 (2020)
The wide distribution of infections-related pathogenic microbes is almost related to the contamination of food and/or drinking water. The current applied treatments face some limitations. In the current study, k-carrageenan polymer was used as suppor
Externí odkaz:
https://doaj.org/article/ce78e40575744f3f9f815ec492604529
Autor:
Irene Müller, Kathleen Pappritz, Konstantinos Savvatis, Kerstin Puhl, Fengquan Dong, Muhammad El-Shafeey, Nazha Hamdani, Isabell Hamann, Michel Noutsias, Carmen Infante-Duarte, Wolfgang A Linke, Sophie Van Linthout, Carsten Tschöpe
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182643 (2017)
Studies on inflammatory disorders elucidated the pivotal role of the CX3CL1/CX3CR1 axis with respect to the pathophysiology and diseases progression. Coxsackievirus B3 (CVB3)-induced myocarditis is associated with severe cardiac inflammation, which m
Externí odkaz:
https://doaj.org/article/8adfa9f2ae684b97a588dc84787a2dc8
Autor:
Beatrice Tolksdorf, Henry Fechner, Jens Kurreck, Kathleen Pappritz, Michele Solimena, Antje Beling, Lisanne Heimann, Klaus-Peter Knoch, Babette Dieringer, Markian Pryshliak, Muhammad El-Shafeey, Ahmet Hazini, Karin Klingel
Publikováno v:
Human Gene Therapy. 32:216-230
Coxsackievirus B3 (CVB3) has strong oncolytic activity in colorectal carcinoma but it also infects the pancreas and the heart. To improve the safety of the virus, here we investigated whether pancreas and cardiac toxicity can be prevented by insertio
Autor:
Huda Alghamdii, Sulaiman A. Alrumman, Ali G. Alshehri, M. A. Abu-Saied, Muhammad El-Shafeey, Mohmed Al-Khatani, Tarek H. Taha, Mohamed Elnouby, Mahmoud Moustafa, Ali A. Shati, Saad Alamri
Publikováno v:
International Journal of Biological Macromolecules. 168:116-123
Wide dissemination of pesticides for protecting plants against pests has resulted in high production of un-infected crops but higher environmental pollution. High percentages of pesticides are released to the environment and finally use water as the
Autor:
Muhammad El-Shafeey, M.S. Mohy Eldin, Mohamed A. Hassan, Tamer M. Tamer, Katarína Valachová, Ahmed M. Omer, Ladislav Šoltés
Publikováno v:
Journal of Biotechnology. 310:103-113
The inflammation of chronic wounds generally causes delaying their healing process. The present work aims to formulate a wound dressing polyelectrolyte membrane based on chitosan (Ch) and sodium hyaluronate (HA) loaded with glutathione (GSH). The mem
Autor:
Tamer M. Tamer, Mohamed A. Hassan, Ahmed M. Omer, M.S. Mohy Eldin, Muhammad El-Shafeey, Katarína Valachová, Ladislav Šoltés
Publikováno v:
International journal of biological macromolecules. 166
Antioxidant and antimicrobial wound dressings are the most favorable for acute and chronic wounds treatment. Herein, we formulated a multifunctional polyelectrolyte wound dressing membrane on the basis of chitosan (Ch) and hyaluronan (HA) enhanced by