Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Muhammad Chatha"'
Autor:
Jared W. Young, Arpi Minassian, Benjamin Z Roberts, Adam L. Halberstadt, Yinong V He, Muhammad Chatha, Igor Grant, Mark A. Geyer
Publikováno v:
International Journal of Neuropsychopharmacology
Background HIV-associated neurocognitive disorder (HAND) is commonly observed in persons living with HIV (PWH) and is characterized by cognitive deficits implicating disruptions of fronto-striatal neurocircuitry. Such circuitry is also susceptible to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6769a13421d1f9ffbb81c855c04febf
https://doi.org/10.1093/ijnp/pyab053
https://doi.org/10.1093/ijnp/pyab053
Autor:
Adam L. Halberstadt, Stephen J. Chapman, Simon D. Brandt, Muhammad Chatha, Emilie I. Anderson, Lauren J. Laskowski, John D. McCorvy, Adam K. Klein
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] The 5-HT(2A) receptor is thought to be the primary target for psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine) and other serotonergic hallucinogens (psychedelic drugs). Although a large amount of experimental work has been conduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93c51f5bec51d91b7a338c55c756fb3
https://doi.org/10.1021/acsptsci.0c00176
https://doi.org/10.1021/acsptsci.0c00176
Autor:
Simon Jademyr, Emil Märcher-Rørsted, Muhammad Chatha, Adam K. Klein, Anders A. Jensen, Jesper L. Kristensen, Adam L. Halberstadt
Publikováno v:
ACS Chemical Neuroscience. 11:1238-1244
The 2,5-dimethoxyphenethylamine (2,5-PEA) scaffold is recognized as a motif conferring potent agonist activity at the serotonin 2A receptor (5-HT2AR). The 2,5-dimethoxy motif is present in several classical phenethylamine psychedelics such as 2,4,5-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffaf702f32611a729f0bad048af65de
https://doi.org/10.1021/acschemneuro.0c00129
https://doi.org/10.1021/acschemneuro.0c00129
Publikováno v:
Cogn Affect Behav Neurosci
The HIV transgenic (HIVtg) rat is a commonly used animal model of chronic HIV infection that exhibits a wide range of cognitive deficits. To date, relatively little work has been conducted on these rats’ capacity for reversal learning, an assay of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab6ac8be1bbe453edf55f9900a9ef58
https://pubmed.ncbi.nlm.nih.gov/34312815
https://pubmed.ncbi.nlm.nih.gov/34312815
Publikováno v:
Journal of Psychopharmacology. 33:406-414
Background: In recent years, there has been increasing scientific interest in the effects and pharmacology of serotonergic hallucinogens. While a large amount of experimental work has been conducted to characterize the behavioral response to hallucin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e7b57904cda3cd81d69d60d31712a4
https://doi.org/10.1177/0269881119826610
https://doi.org/10.1177/0269881119826610
Publikováno v:
Neuropharmacology
Serotonergic hallucinogens such as lysergic acid diethylamide (LSD) induce head twitches in rodents via 5-HT2A receptor activation. The goal of the present investigation was to determine whether a correlation exists between the potency of hallucinoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1adfed1acb1d22544573cd6564e3d618
https://escholarship.org/uc/item/7pz549b9
https://escholarship.org/uc/item/7pz549b9
Autor:
Laura B Valenzuela, Adam L. Halberstadt, Landon M. Klein, Jason Wallach, Alexander Stratford, David E. Nichols, Muhammad Chatha, Simon D. Brandt
Publikováno v:
Psychopharmacology, vol 236, iss 2
RationaleThe lysergamide lysergic acid diethylamide (LSD) is a prototypical classical hallucinogen with remarkably high potency. LSD remains a popular recreational drug but is also becoming an important research tool for medical and neuroscience stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f1422d9a465a274543e122e6800e05
https://doi.org/10.1007/s00213-018-5055-9
https://doi.org/10.1007/s00213-018-5055-9
Autor:
Alexander Stratford, Lea Wagmann, Adam K. Klein, Adam L. Halberstadt, Muhammad Chatha, Simon D. Brandt, Markus R. Meyer, John D. McCorvy
Publikováno v:
Neuropharmacology
The ergoline d-lysergic acid diethylamide (LSD) is one of the most potent psychedelic drugs. 1-Acetyl-LSD (ALD-52), a derivative of LSD containing an acetyl group on the indole nitrogen, also produces psychedelic effects in humans and has about the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a2c13dd66a05d7b406f219a9e57802
https://doi.org/10.1016/j.neuropharm.2019.107856
https://doi.org/10.1016/j.neuropharm.2019.107856
Autor:
Emil Märcher-Rørsted, Anna U. Odland, Adam L. Halberstadt, Nikolaj Speth, Mikael Palner, Jesper L. Kristensen, Jesper T. Andreasen, Hans Bräuner-Osborne, Muhammad Chatha, Martin Hansen, Gudrun Liebscher, Anders A. Jensen
Publikováno v:
Biochemical Pharmacology. 177:113979
The remarkable effects exhibited by classical psychedelics in recent clinical trials have spawned considerable interest in 5-HT2A receptor (5-HT2AR) activation as a treatment strategy for several psychiatric/cognitive disorders. In this study we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f211470c6e9d4c0798e04e40a94e228
https://doi.org/10.1016/j.bcp.2020.113979
https://doi.org/10.1016/j.bcp.2020.113979
In recent years, rigid analogues of phenylalkylamine hallucinogens have appeared as recreational drugs. Examples include 2-(8-bromo-2,3,6,7-tetrahydrobenzo[1,2-b:4,5-b′]difuran-4-yl)ethan-1-amine (2C-B-FLY) and 1-(8-bromobenzo[1,2-b;4,5-b’]difura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f021ae64ff57c0d6f6dd954613c4040
https://europepmc.org/articles/PMC6863604/
https://europepmc.org/articles/PMC6863604/