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pro vyhledávání: '"Muhammad Bakhait Rahmat"'
Publikováno v:
Oncotarget
The Hippo pathway regulates cell proliferation, survival, apoptosis and differentiation. During carcinogenesis, members of the Hippo pathway are mutated to avoid anoikis and promote anchorage independent growth. Although many regulators of the Hippo
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Scientific Reports
Scientific Reports
Endothelial cells adopt unique cell fates during sprouting angiogenesis, differentiating into tip or stalk cells. The fate selection process is directed by Delta-Notch lateral inhibition pathway. Classical Delta-Notch models produce a spatial pattern
Publikováno v:
Oncotarget
Autor:
Muhammad Bakhait Rahmat
The Hippo pathway has gained immense attention due to its key role in regulating organ size as well as its relevance to tissue regeneration and cancer. The pathway is renowned for regulating the two transcriptional co-activators, YAP and TAZ, which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c1dc0373afc8d075f0703e3c1a8269
https://hdl.handle.net/10356/82593
https://hdl.handle.net/10356/82593
Publikováno v:
Biophysical Journal. 112:279a-280a
During sprouting angiogenesis, endothelial cells take on a spatial pattern of unique cell fates, becoming either the tip cell or the stalk cell. This process of fate selection is guided by lateral inhibition via the Delta-Notch signalling pathway. Cl