Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Muhamad Noor Alfarizal Kamarudin"'
Autor:
Yugendran Jegathesan, Pashaun Paveen Stephen, Isra Saif Eldin Eisa Sati, Prakrithi Narayanan, Mastura Monif, Muhamad Noor Alfarizal Kamarudin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 172, Iss , Pp 116277- (2024)
Notorious for its high mortality rate, the current standard treatment for high-grade gliomas remains a challenge. This is largely due to the complex heterogeneity of the tumour coupled with dysregulated molecular mechanisms leading to the development
Externí odkaz:
https://doaj.org/article/7f90560484ee4dc2b770db699cb49865
Autor:
Min Yee Chow, Syafiq Asnawi Zainal Abidin, Jeyanthy Eswaran, Rakesh Naidu, Muhamad Noor Alfarizal Kamarudin
Publikováno v:
IBRO Neuroscience Reports, Vol 15, Iss , Pp S546- (2023)
Externí odkaz:
https://doaj.org/article/a84b99d8fee84426926e82a38ee5a6bf
Autor:
Kah Hui Wong, Lee Wei Lim, Nur Shahirah Mohd Hisam, Muhamad Noor Alfarizal Kamarudin, Hariprasath Lakshmanan
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/c3195d005c1a40e195fe294303a44983
Autor:
Dexter Hoi Long Leung, Brandon Wee Siang Phon, Mageswary Sivalingam, Ammu Kutty Radhakrishnan, Muhamad Noor Alfarizal Kamarudin
Publikováno v:
Biology, Vol 12, Iss 6, p 818 (2023)
Glioblastoma (GBM) mesenchymal (MES) transition can be regulated by long non-coding RNAs (lncRNAs) via modulation of various factors (Epithelial-to-Mesenchymal (EMT) markers, biological signalling, and the extracellular matrix (ECM)). However, unders
Externí odkaz:
https://doaj.org/article/c9d5391677ed4d81a6338e4863fa9e10
Autor:
Brandon Wee Siang Phon, Saatheeyavaane Bhuvanendran, Qasim Ayub, Ammu Kutty Radhakrishnan, Muhamad Noor Alfarizal Kamarudin
Publikováno v:
Biology, Vol 12, Iss 5, p 648 (2023)
A paradigm shift in preclinical evaluations of new anticancer GBM drugs should occur in favour of 3D cultures. This study leveraged the vast genomic data banks to investigate the suitability of 3D cultures as cell-based models for GBM. We hypothesise
Externí odkaz:
https://doaj.org/article/6160358713924b858816409471e6c43b
Publikováno v:
Nutrients, Vol 15, Iss 4, p 797 (2023)
High-grade adult-type diffuse gliomas are the most common and deadliest malignant adult tumors of the central nervous system. Despite the advancements in the multimodality treatment of high-grade adult-type diffuse gliomas, the five-year survival rat
Externí odkaz:
https://doaj.org/article/0c7919d6bd254577aed0147d0d47c661
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-23 (2019)
Abstract Growing evidence showed the increased prevalence of cancer incidents, particularly colorectal cancer, among type 2 diabetic mellitus patients. Antidiabetic medications such as, insulin, sulfonylureas, dipeptyl peptidase (DPP) 4 inhibitors an
Externí odkaz:
https://doaj.org/article/8a6fe1ab58044a0fbbfd30f7cf960637
Autor:
Dina El-Rabie Osman, Brandon Wee Siang Phon, Muhamad Noor Alfarizal Kamarudin, Stephen Navendran Ponnampalam, Ammu Kutty Radhakrishnan, Saatheeyavaane Bhuvanendran
Publikováno v:
Nutrients, Vol 14, Iss 14, p 2873 (2022)
Glioblastoma (GBM), a highly lethal form of adult malignant gliomas with little clinical advancement, raises the need for alternative therapeutic approaches. Lipid-soluble vitamins have gained attention in malignant brain tumors owing to their pleiot
Externí odkaz:
https://doaj.org/article/0d6b0ea2501b40b0b31b1d524f0ec15b
Publikováno v:
Nutrients, Vol 13, Iss 3, p 950 (2021)
Glioblastoma (GBM) is the most malignant brain tumor and accounts for most adult brain tumors. Current available treatment options for GBM are multimodal, which include surgical resection, radiation, and chemotherapy. Despite the significant advances
Externí odkaz:
https://doaj.org/article/7c28e05246db44c7af3b7a9579ca87b4
Autor:
Jean Yin Tan, Ipalawattage Vindya Stephnie Wijesinghe, Muhamad Noor Alfarizal Kamarudin, Ishwar Parhar
Publikováno v:
Cancers, Vol 13, Iss 4, p 607 (2021)
Paediatric gliomas categorised as low- or high-grade vary markedly from their adult counterparts, and denoted as the second most prevalent childhood cancers after leukaemia. As compared to adult gliomas, the studies of diagnostic and prognostic bioma
Externí odkaz:
https://doaj.org/article/c2ef4acd4c4242c49b2c648c06f76ca2