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Role of ErbB1 in the Underlying Mechanism of Lapatinib-Induced Diarrhoea: A Review

Autor: Raja Sharin, Raja Nur Firzanah Syaza, Khan, Jesmine, Ibahim, Mohamad Johari, Muhamad, Mudiana, Bowen, Joanne, Wan Mohamad Zain, Wan Nor I’zzah

Publikováno v: BioMed Research International.

Lapatinib, an orally administered small-molecule tyrosine kinase inhibitor (SM-TKI), is an effective treatment for ErbB2-positive breast cancer. However, its efficacy as one of the targeted cancer therapies has been hampered by several adverse effect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=hindawi_publ::24224fc579fc2549f056930107da2e8f

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Establishment of humanised xenograft models as in vivo study for lung metastasis of osteosarcoma.

Autor: Khamarudin F; Department of Biochemistry and Molecular Medicine, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia.; Institute for Medical Molecular Biotechnology, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia., Muhamad M; Department of Biochemistry and Molecular Medicine, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia., Johari Ibahim M; Department of Biochemistry and Molecular Medicine, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia., Wan Mohamad Zain WNI; Department of Biochemistry and Molecular Medicine, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia., Aziz MA; Department of Pathology, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia., Adib Ridzuan NR; Department of Anatomy, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia., Ab-Rahim S; Department of Biochemistry and Molecular Medicine, Universiti Teknologi MARA, Sungai Buloh, 47000 Selangor, Malaysia.

Publikováno v: Immunotherapy advances [Immunother Adv] 2024 Mar 23; Vol. 4 (1), pp. ltae002. Date of Electronic Publication: 2024 Mar 23 (Print Publication: 2024).