Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors

Autor: Comazzetto, Stefano, Cassidy, Daniel L., DeVilbiss, Andrew W., Jeffery, Elise C., Ottesen, Bethany R., Reyes, Amanda R., Paul, Animesh, Bansal, Suraj, Xie, Stephanie Z., Muh, Sarah, Mathews, Thomas P., Chen, Brandon, Zhao, Zhiyu, Morrison, Sean J.

Publikováno v: In Blood September 2024

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Ascorbate depletion increases quiescence and self-renewal potential in hematopoietic stem cells and multipotent progenitors.

Autor: Comazzetto S; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Cassidy DL; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., DeVilbiss AW; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Jeffery EC; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Ottesen BR; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Reyes AR; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Muh S; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Mathews TP; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Chen B; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Zhao Z; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Morrison SJ; Children's Research Institute and the Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 02. Date of Electronic Publication: 2024 Apr 02.