Human Umbilical Cord Perivascular Cells Prevent Tumor Growth in a Melanoma Tumor-Bearing Mouse Model and Modulate Breast Cancer and Melanoma Cells in a Cell Line-Dependent Manner In Vitro

Autor: Lianet Lopez, Hannah Shuster-Hyman, Eden Marco, Hasna Khan, Avishai Gasner, Aleksandra Uzelac, Brandon Wyse, Poonam Mander, Mugundhine Sangaralingam, Joseph Fish, Ariel Gorodensky, Samar Mouazz, Amanda Kauffman, Denis Gallagher, Andrée Gauthier-Fisher, Clifford L. Librach

Publikováno v: Stem Cells International, Vol 2023 (2023)

First trimester (FTM) and term human umbilical cord perivascular cells are promising mesenchymal stromal cell candidates to mitigate side effects of oncotherapy, but their safety for cancer patients remains to be determined. This study was designed t

Externí odkaz: https://doaj.org/article/d8e68fc7c05546b9a0c452adbb4a4a7b

Transcriptomics of cumulus cells – a window into oocyte maturation in humans

Autor: Hanna Balakier, Noga Fuchs Weizman, Clifford Librach, Brandon A. Wyse, Mugundhine Sangaralingam, Seth Kadish

Publikováno v: Journal of Ovarian Research, Vol 13, Iss 1, Pp 1-14 (2020)
Journal of Ovarian Research

BackgroundCumulus cells (CC) encapsulate growing oocytes and support their growth and development. Transcriptomic signatures of CC have the potential to serve as valuable non-invasive biomarkers for oocyte competency and potential. The present siblin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2fca2ab3485329cab9299f5e30a221
http://link.springer.com/article/10.1186/s13048-020-00696-7

Towards Improving Embryo Prioritization: Parallel Next Generation Sequencing of DNA and RNA from a Single Trophectoderm Biopsy

Autor: Noga Fuchs Weizman, Zenon Ibarrientos, Brandon A. Wyse, Valeriy Kuznyetsov, Ran Antes, Mugundhine Sangaralingam, Clifford Librach, Svetlana Madjunkova, Gelareh Motamedi

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)

Improved embryo prioritization is crucial in optimizing the results in assisted reproduction, especially in light of increasing utilization of elective single embryo transfers. Embryo prioritization is currently based on morphological criteria and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99219d5e4acea2574efa66fb79375259
https://pubmed.ncbi.nlm.nih.gov/30814554

Real-time PCR using FRET technology for Old World cutaneous leishmaniasis species differentiation

Autor: Francine Pratlong, Juan Mendez, Momar Ndao, Michael Libman, Christophe Ravel, Patrick Bastien, Milli Nath-Chowdhury, Mugundhine Sangaralingam

Publikováno v: Parasites and Vectors
Parasites and Vectors, BioMed Central, 2016, 9, pp.255. ⟨10.1186/s13071-016-1531-4⟩
Parasites & Vectors
Parasites & Vectors, 2016, 9, pp.255. ⟨10.1186/s13071-016-1531-4⟩

International audience; BACKGROUND:Recently, there has been a re-emergence of cutaneous leishmaniasis in endemic countries and an increase in imported cases in non-endemic countries by travelers, workers, expatriates, immigrants, and military force p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7d8fafb729ba7cf19ffacd522fafe2
https://hal.archives-ouvertes.fr/hal-01868539/document

Heterogeneity of oligodendrocyte progenitor cells in adult human brain

Autor: Vijayaraghava T.S. Rao, Jenea M. Bin, Jack P. Antel, Pavel Gris, Soo Yuen Leong, Mugundhine Sangaralingam, Timothy E. Kennedy

Publikováno v: Annals of Clinical and Translational Neurology

Objective Remyelination in multiple sclerosis has been attributed to the presence of oligodendrocyte progenitor cells (OPCs) in brain parenchyma. However, the precise identity of these progenitors is poorly defined. Here, we characterized populations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0df40f69ed8aeaf2a39ea7c7bb7c1129
https://pubmed.ncbi.nlm.nih.gov/25590039