Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mugdha R. Suryawanshi"'
Publikováno v:
International Journal of Current Pharmaceutical Research. :36-39
Objective: To develop and validate simple, rapid, linear, accurate, precise and economical UV Spectroscopic method for estimation of Abacavir in tablet dosage form. Methods: The drug is freely soluble in analytical grade methanol. The drug was identi
Publikováno v:
International Journal of Pharmacy and Pharmaceutical Sciences. :114-121
Objective: The study was aimed to investigate the cytotoxic effect of S-5H-[1,2,4]-triazino (5,6-b) indol-3-yl-3,4-phenylethane-thioate derivatives as epidermal growth factor Receptor (EGFR) inhibitors. Methods: In the present study 14 novel triazine
Autor:
Kakasaheb R. Mahadik, Radha Charan Dash, Mugdha R. Suryawanshi, Sharad H. Bhosale, Suhas M. Shelke
Publikováno v:
Medicinal Chemistry. 8:1069-1075
A series of novel N,N-diphenyl-2-[4-(substituted phenyl)piperazin-1-yl]acetamides was designed, synthesized and evaluated for anti-dopaminergic activity, anti-serotonergic activity and catalepsy induction studies in mice as an approach to novel poten
Autor:
Suhas M. Shelke, Mugdha R. Suryawanshi, Ashish M. Kanhed, Kakasaheb R. Mahadik, Radha Charan Dash, Sharad H. Bhosale
Publikováno v:
Molecular Diversity. 16:367-375
The dopamine D(2) receptor is involved in the etiology of a number of disorders, such as Parkinson's disease, Huntington's Chorea, tardive dyskinesia and schizophrenia. Antagonism of D(2) receptors is implicated in the treatment of various psychiatri
Autor:
Suhas M. Shelke, Mugdha R. Suryawanshi, Kakasaheb R. Mahadik, Radha Charan Dash, Sharad H. Bhosale
Publikováno v:
Medicinal Chemistry Research. 20:29-35
The present research paper reports the synthesis and biological evaluation of 6-(3-substitutedpropoxyl)benzo[d][1,3]oxathiol-2-ones as potential atypical antipsychotic agents. Accordingly, 10 derivatives with either amino or aryloxy substituents were
Publikováno v:
European journal of medicinal chemistry. 74
This article describes the design of biphenyl moiety linked with aryl piperazine and syntheses of fourteen 1-(biphenyl-4-yl)-2-[4-(substituted phenyl)-piperazin-1-yl]ethanone derivatives along with their pharmacological evaluation for antipsychotic a
Autor:
Mugdha R. Suryawanshi, Kakasaheb R. Mahadik, Radha Charan Dash, Sharad H. Bhosale, Suhas M. Shelke
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(8)
Monoamine oxidase-A (MAO-A) inhibitors are of particular importance in the treatment of depressive disorders. Herein described is pharmacophore generation and atom-based 3D-QSAR analysis of previously reported pyrrole based MAO-A inhibitors in order