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DNA damage in human whole blood caused by radiopharmaceuticals evaluated by the comet assay.

Autor: Schmeiser HH; Division of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld, Heidelberg, Germany., Muehlbauer KR; Division of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld, Heidelberg, Germany., Mier W; Department of Nuclear Medicine, University Hospital Heidelberg, Im Neuenheimer Feld, Heidelberg, Germany., Baranski AC; Division of Radiopharmaceutical Development, German Cancer Consortium (DKTK), Partner Site Freiburg, and Department of Nuclear Medicine, University Medical Center, Hugstetter Straße, Freiburg, Germany., Neels O; Division of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld, Heidelberg, Germany.; Division of Radiopharmaceutical Chemistry, German Cancer Consortium (DKTK), Im Neuenheimer FeldHeidelberg, Germany., Dimitrakopoulou-Strauss A; Clinical Cooperation Unit Nuclear Medicine, Germany., Schmezer P; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld Heidelberg, Germany., Kratochwil C; Department of Nuclear Medicine, University Hospital Heidelberg, Im Neuenheimer Feld, Heidelberg, Germany., Bruchertseifer F; European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security, Karlsruhe, Germany., Morgenstern A; European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security, Karlsruhe, Germany., Kopka K; Division of Radiopharmaceutical Chemistry, German Cancer Research Center (DKFZ), Im Neuenheimer Feld, Heidelberg, Germany.; Division of Radiopharmaceutical Chemistry, German Cancer Consortium (DKTK), Im Neuenheimer FeldHeidelberg, Germany.

Publikováno v: Mutagenesis [Mutagenesis] 2019 Sep 20; Vol. 34 (3), pp. 239-244.

Modelling mutational landscapes of human cancers in vitro.

Autor: Olivier M; Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, 69008 Lyon, France., Weninger A; German Cancer Research Center (Deutsches Krebsforschungszentrum), D69120 Heidelberg, Germany., Ardin M; Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, 69008 Lyon, France., Huskova H; Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, 69008 Lyon, France., Castells X; Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, 69008 Lyon, France., Vallée MP; Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, 69008 Lyon, France., McKay J; Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, 69008 Lyon, France., Nedelko T; German Cancer Research Center (Deutsches Krebsforschungszentrum), D69120 Heidelberg, Germany., Muehlbauer KR; German Cancer Research Center (Deutsches Krebsforschungszentrum), D69120 Heidelberg, Germany., Marusawa H; Department of Gastroenterology and Hepatology, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan., Alexander J; Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, United Kingdom., Hazelwood L; Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, United Kingdom., Byrnes G; Biostatistics Group, International Agency for Research on Cancer, 69008 Lyon, France., Hollstein M; 1] German Cancer Research Center (Deutsches Krebsforschungszentrum), D69120 Heidelberg, Germany [2] Faculty of Medicine and Health, University of Leeds, Leeds LS2 9JT, United Kingdom., Zavadil J; Molecular Mechanisms and Biomarkers Group, International Agency for Research on Cancer, 69008 Lyon, France.

Publikováno v: Scientific reports [Sci Rep] 2014 Mar 27; Vol. 4, pp. 4482. Date of Electronic Publication: 2014 Mar 27.

Further studies with a cell immortalization assay to investigate the mutation signature of aristolochic acid in human p53 sequences.

Autor: Feldmeyer N; Department of Genetic Alterations in Carcinogenesis, Deutsches Krebsforschungszentrum (German Cancer Research Center), D-69120 Heidelberg, Germany., Schmeiser HH, Muehlbauer KR, Belharazem D, Knyazev Y, Nedelko T, Hollstein M

Publikováno v: Mutation research [Mutat Res] 2006 Sep 28; Vol. 608 (2), pp. 163-8. Date of Electronic Publication: 2006 Jul 10.