Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mudita, Pincha"'
Autor:
Philipp Beckhove, Viktor Umansky, Jürgen Weitz, Christoph Reissfelder, Christel Herold-Mende, Steffen Dettling, Helge Frebel, Florian Schuetz, Christoph Domschke, Alexandra Sevko, Andreas Bonertz, Michael Hillier, Christopher Breyer, Ludmila Umansky, Mudita Pincha, Xiaoying Hu, Maria Xydia, Anchana Rathinasamy, Hans-Henning Böhm, Yingzi Ge
Endogenous antitumor effector T-cell responses and immune-suppressive regulatory T cells (Treg) critically influence the prognosis of patients with cancer, yet many of the mechanisms of how this occurs remain unresolved. On the basis of an analysis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b45291cdb5c5112c0e94cccb89461c
https://doi.org/10.1158/2326-6066.c.6549904
https://doi.org/10.1158/2326-6066.c.6549904
Autor:
Philipp Beckhove, Viktor Umansky, Jürgen Weitz, Christoph Reissfelder, Christel Herold-Mende, Steffen Dettling, Helge Frebel, Florian Schuetz, Christoph Domschke, Alexandra Sevko, Andreas Bonertz, Michael Hillier, Christopher Breyer, Ludmila Umansky, Mudita Pincha, Xiaoying Hu, Maria Xydia, Anchana Rathinasamy, Hans-Henning Böhm, Yingzi Ge
Supplemental Figures S1 to S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7395cd4ba0158d1981214789f1632607
https://doi.org/10.1158/2326-6066.22542394.v1
https://doi.org/10.1158/2326-6066.22542394.v1
Autor:
Jean J.L. Tessier, Christian Klein, Jean Gudas, Ian A. Wilson, Dominik Rüttinger, Pablo Umana, Marina Bacac, Peter Brünker, Claudia Ferrara, Christina Claus, Johannes Sam, Valeria G. Nicolini, Marine Richard, Preethi L.B. Mohan, Maria Amann, Mudita Pincha, Tapan K. Nayak, Green Zhang, Chenyu Lee, Daulet Satpayev, Filippo Marchioni, Jason M. Romero, Michael Torgov, Fang Jia, Charles Zamilpa, Ziyue Karen Jiang, Alessandro Mascioni, Tove Olafsen, Christoph M. Griessinger
Figure S6 shows the correlation of CD8-IHC and tumoruptake as determined by gamma-counting or PET.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6a13fe28eabcec76522fa717e14224
https://doi.org/10.1158/0008-5472.22425051.v1
https://doi.org/10.1158/0008-5472.22425051.v1
Autor:
Jean J.L. Tessier, Christian Klein, Jean Gudas, Ian A. Wilson, Dominik Rüttinger, Pablo Umana, Marina Bacac, Peter Brünker, Claudia Ferrara, Christina Claus, Johannes Sam, Valeria G. Nicolini, Marine Richard, Preethi L.B. Mohan, Maria Amann, Mudita Pincha, Tapan K. Nayak, Green Zhang, Chenyu Lee, Daulet Satpayev, Filippo Marchioni, Jason M. Romero, Michael Torgov, Fang Jia, Charles Zamilpa, Ziyue Karen Jiang, Alessandro Mascioni, Tove Olafsen, Christoph M. Griessinger
Figure S2 shows the PET scans of each experimental mouse of the CEA-4-1BBL/CEA-TCB study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386728eedaaa2308958361cbabde4e0c
https://doi.org/10.1158/0008-5472.22425066
https://doi.org/10.1158/0008-5472.22425066
Autor:
Jean J.L. Tessier, Christian Klein, Jean Gudas, Ian A. Wilson, Dominik Rüttinger, Pablo Umana, Marina Bacac, Peter Brünker, Claudia Ferrara, Christina Claus, Johannes Sam, Valeria G. Nicolini, Marine Richard, Preethi L.B. Mohan, Maria Amann, Mudita Pincha, Tapan K. Nayak, Green Zhang, Chenyu Lee, Daulet Satpayev, Filippo Marchioni, Jason M. Romero, Michael Torgov, Fang Jia, Charles Zamilpa, Ziyue Karen Jiang, Alessandro Mascioni, Tove Olafsen, Christoph M. Griessinger
CD8-expressing T cells are the main effector cells in cancer immunotherapy. Treatment-induced changes in intratumoral CD8+ T cells may represent a biomarker to identify patients responding to cancer immunotherapy. Here, we have used a 89Zr-radiolabel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f178a6cff9e64f039bd22cb7364792b
https://doi.org/10.1158/0008-5472.c.6511935.v1
https://doi.org/10.1158/0008-5472.c.6511935.v1
Autor:
Jean J.L. Tessier, Christian Klein, Jean Gudas, Ian A. Wilson, Dominik Rüttinger, Pablo Umana, Marina Bacac, Peter Brünker, Claudia Ferrara, Christina Claus, Johannes Sam, Valeria G. Nicolini, Marine Richard, Preethi L.B. Mohan, Maria Amann, Mudita Pincha, Tapan K. Nayak, Green Zhang, Chenyu Lee, Daulet Satpayev, Filippo Marchioni, Jason M. Romero, Michael Torgov, Fang Jia, Charles Zamilpa, Ziyue Karen Jiang, Alessandro Mascioni, Tove Olafsen, Christoph M. Griessinger
Figure S4 shows the IHC analysis for tumor density, necrosis and blood vessels.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b19176c6935960eb60f12f28354a3c9
https://doi.org/10.1158/0008-5472.22425060
https://doi.org/10.1158/0008-5472.22425060
Autor:
Jean J.L. Tessier, Christian Klein, Jean Gudas, Ian A. Wilson, Dominik Rüttinger, Pablo Umana, Marina Bacac, Peter Brünker, Claudia Ferrara, Christina Claus, Johannes Sam, Valeria G. Nicolini, Marine Richard, Preethi L.B. Mohan, Maria Amann, Mudita Pincha, Tapan K. Nayak, Green Zhang, Chenyu Lee, Daulet Satpayev, Filippo Marchioni, Jason M. Romero, Michael Torgov, Fang Jia, Charles Zamilpa, Ziyue Karen Jiang, Alessandro Mascioni, Tove Olafsen, Christoph M. Griessinger
Figure S1 shows the in vitro tumor cell lysis mediated by CEA-TCB and CEA-4-1BBL) or FOLR1-TCB ni presence of the CD8 Mb IAB22M2C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::064cd57ca8db13a841e99ef681cfbccc
https://doi.org/10.1158/0008-5472.22425069
https://doi.org/10.1158/0008-5472.22425069
Autor:
Jean J.L. Tessier, Christian Klein, Jean Gudas, Ian A. Wilson, Dominik Rüttinger, Pablo Umana, Marina Bacac, Peter Brünker, Claudia Ferrara, Christina Claus, Johannes Sam, Valeria G. Nicolini, Marine Richard, Preethi L.B. Mohan, Maria Amann, Mudita Pincha, Tapan K. Nayak, Green Zhang, Chenyu Lee, Daulet Satpayev, Filippo Marchioni, Jason M. Romero, Michael Torgov, Fang Jia, Charles Zamilpa, Ziyue Karen Jiang, Alessandro Mascioni, Tove Olafsen, Christoph M. Griessinger
Figure S5 shows PET scans of each experimental animal of the FOLR1-TCB study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ab6d448ded1fa9a8b1c0cf1bce3f85e
https://doi.org/10.1158/0008-5472.22425054
https://doi.org/10.1158/0008-5472.22425054
Autor:
Jean J.L. Tessier, Christian Klein, Jean Gudas, Ian A. Wilson, Dominik Rüttinger, Pablo Umana, Marina Bacac, Peter Brünker, Claudia Ferrara, Christina Claus, Johannes Sam, Valeria G. Nicolini, Marine Richard, Preethi L.B. Mohan, Maria Amann, Mudita Pincha, Tapan K. Nayak, Green Zhang, Chenyu Lee, Daulet Satpayev, Filippo Marchioni, Jason M. Romero, Michael Torgov, Fang Jia, Charles Zamilpa, Ziyue Karen Jiang, Alessandro Mascioni, Tove Olafsen, Christoph M. Griessinger
Figure S3 shows autoradiography slides after CEA-4-1BBL/CEA-TCB single or combo treatment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10e85e5808896134b092e6b4c4b8e5c7
https://doi.org/10.1158/0008-5472.22425063
https://doi.org/10.1158/0008-5472.22425063
Autor:
Marine Richard, Jason Romero, Daulet Satpayev, Peter Brünker, Filippo Marchioni, Mudita Pincha, Tapan K. Nayak, Pablo Umana, Nicolini Valeria G, Claudia Ferrara, Marina Bacac, Maria Amann, Christoph M. Griessinger, Fang Jia, Charles Zamilpa, Michael Torgov, Christian Klein, Tove Olafsen, Jean Tessier, Dominik Rüttinger, Alessandro Mascioni, Christina Claus, Ian Andrew Wilson, Jean Gudas, Johannes Sam, Preethi Latha Bhavani Mohan, Ziyue Karen Jiang, Green Zhang, Chenyu Lee
Publikováno v:
Cancer Research. 80:2903-2913
CD8-expressing T cells are the main effector cells in cancer immunotherapy. Treatment-induced changes in intratumoral CD8+ T cells may represent a biomarker to identify patients responding to cancer immunotherapy. Here, we have used a 89Zr-radiolabel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc77094c3b0b3f652e7fc1b51864a2c4
https://doi.org/10.1158/0008-5472.can-19-3269
https://doi.org/10.1158/0008-5472.can-19-3269
