Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mudathir Alim"'
Autor:
Suzannah J Rihn, Sam J Wilson, Nick J Loman, Mudathir Alim, Saskia E Bakker, David Bhella, Robert J Gifford, Frazer J Rixon, Paul D Bieniasz
Publikováno v:
PLoS Pathogens, Vol 9, Iss 6, p e1003461 (2013)
Genetic robustness, or fragility, is defined as the ability, or lack thereof, of a biological entity to maintain function in the face of mutations. Viruses that replicate via RNA intermediates exhibit high mutation rates, and robustness should be par
Externí odkaz:
https://doaj.org/article/34a40bd4ec5d4f0b983759833986b91d
Autor:
John W. Schoggins, Trinity Zang, Fengwen Zhang, Tonya Kueck, Melissa Kane, Mudathir Alim, Suzannah J. Rihn, Charles M. Rice, Paul D. Bieniasz, Sam J. Wilson
Publikováno v:
Cell Host & Microbe
Summary Interferons (IFNs) exert their anti-viral effects by inducing the expression of hundreds of IFN-stimulated genes (ISGs). The activity of known ISGs is insufficient to account for the antiretroviral effects of IFN, suggesting that ISGs with an
Autor:
Charles M. Rice, Mudathir Alim, John W. Schoggins, Sebla B. Kutluay, Nolwenn Jouvenet, Paul D. Bieniasz, Julia Bitzegeio, Trinity Zang, Sam J. Wilson
Publikováno v:
Cell Host & Microbe. 12(4):585-597
SummaryThe expression of hundreds of interferon-stimulated genes (ISGs) causes the cellular “antiviral state” in which the replication of many viruses, including HIV-1, is attenuated. We conducted a screen for ISGs that inhibit HIV-1 virion produ
Autor:
Paul D. Bieniasz, Nicholas J. Loman, Saskia E. Bakker, David Bhella, Sam J. Wilson, Mudathir Alim, Suzannah J. Rihn, Frazer J. Rixon
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 9, Iss 6, p e1003461 (2013)
Retrovirology
PLoS Pathogens, Vol 9, Iss 6, p e1003461 (2013)
Retrovirology
Genetic robustness, or fragility, is defined as the ability, or lack thereof, of a biological entity to maintain function in the face of mutations. Viruses that replicate via RNA intermediates exhibit high mutation rates, and robustness should be par