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Neutrophil swarming is crucial for limiting oral mucosal infection by Candida albicans.

Autor: Saraswat D; Department of Oral Biology, University at Buffalo, Buffalo, NY, USA., Rojas IG; Department of Oral Biology, University at Buffalo, Buffalo, NY, USA.; Department of Periodontics and Endodontics, University at Buffalo, Buffalo, NY, USA., Kumar R; Department of Oral Biology, University at Buffalo, Buffalo, NY, USA., Li R; Department of Oral Biology, University at Buffalo, Buffalo, NY, USA.; Department of Restorative Dentistry, University at Buffalo, Buffalo, NY, USA., Salvatori O; Department of Oral Biology, University at Buffalo, Buffalo, NY, USA., Irimia D; Center for Medicine and Surgery, Department of Surgery, Massachusetts General Hospital, Shriners Burns Hospital, Harvard Medical School, Boston, MA, USA., Edgerton M; Department of Oral Biology, University at Buffalo, Buffalo, NY, USA.

Publikováno v: Journal of leukocyte biology [J Leukoc Biol] 2024 Nov 12. Date of Electronic Publication: 2024 Nov 12.

An organotypic oral mucosal infection model to study host-pathogen interactions

Autor: Samantha J Gould, Andrew D Foey, Vehid M Salih

Publikováno v: Journal of Tissue Engineering, Vol 14 (2023)

Early in vitro oral mucosal infection models (OMMs) failed to consider the suitability of the model environment to represent the host immune response. Denture stomatitis (DS) is mediated by Candida albicans , but the role of Staphylococcus aureus rem

Externí odkaz: https://doaj.org/article/f0965c476a4a493f9794136192aab424

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Memory T cells possess an innate-like function in local protection from mucosal infection

Autor: Tanvi Arkatkar, Veronica Davé, Irene Cruz Talavera, Jessica B. Graham, Jessica L. Swarts, Sean M. Hughes, Timothy A. Bell, Pablo Hock, Joe Farrington, Ginger D. Shaw, Anna Kirby, Michael Fialkow, Meei-Li Huang, Keith R. Jerome, Martin T. Ferris, Florian Hladik, Joshua T. Schiffer, Martin Prlic, Jennifer M. Lund

Publikováno v: The Journal of Clinical Investigation, Vol 133, Iss 10 (2023)

Mucosal infections pose a significant global health burden. Antigen-specific tissue-resident T cells are critical to maintaining barrier immunity. Previous studies in the context of systemic infection suggest that memory CD8+ T cells may also provide

Externí odkaz: https://doaj.org/article/c1f6027d12e448b38a3cfc27c143ba2e