Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Muazzam Arif"'
Autor:
Muhammad Tahir Aqeel, Nisar-Ur-Rahman, Arif-ullah Khan, Zaman Ashraf, Samiullah Khan, Muazzam Arif
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 8, Iss 1, Pp 1-11 (2022)
Abstract Background Lysyl oxidase-like 2 (LOXL2) has recently been explored as extremely pivotal protein involved in angiogenesis which results in metastasis of numerous types of cancers. Hence, LOXL2 is an exciting new target for drug development ag
Externí odkaz:
https://doaj.org/article/75284f44e8744eb7b346eed0b90c2b7e
Autor:
Mohsinul Mulk Bacha, Humaira Nadeem, Sumera Zaib, Sadia Sarwar, Aqeel Imran, Shafiq Ur Rahman, Hafiz Saqib Ali, Muazzam Arif, Jamshed Iqbal
Publikováno v:
BMC Chemistry, Vol 15, Iss 1, Pp 1-15 (2021)
Abstract In diabetes, increased accumulation of sorbitol has been associated with diabetic complications through polyol pathway. Aldose reductase (AR) is one of the key factors involved in reduction of glucose to sorbitol, thereby its inhibition is i
Externí odkaz:
https://doaj.org/article/4fa7feffe1c9431f8c8032e1bcd01492
Publikováno v:
BMC Chemistry, Vol 13, Iss 1, Pp 1-13 (2019)
Abstract Background Isoxazole is an important pharmacophore in medicinal chemistry with a wide range of pharmacological activities. The present study deals with the synthesis and evaluation of antinociceptive potential of nine novel 3-substituted-iso
Externí odkaz:
https://doaj.org/article/544eed4efea342a6b5ea4647bc749229
Autor:
Sadia Sarwar, Amani Alghamdi, Jun Qing Yu, Abir Abdullah Alamro, Fazlul Huq, Komal Naeem, Muazzam Arif, Salamat Ullah
Publikováno v:
Drug Design, Development and Therapy
Sadia Sarwar,1,2 Abir A Alamro,3 Amani A Alghamdi,3 Komal Naeem,4 Salamat Ullah,5 Muazzam Arif,6 Jun Qing Yu,1 Fazlul Huq7 1Discipline of Biomedical Sciences, Sydney Medical School, The University of Sydney, Cumberland Campus, Sydney, NSW, Australia;
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0fa8a51b604e4476fa7a05b14673d06
http://europepmc.org/articles/PMC8164677
http://europepmc.org/articles/PMC8164677
Autor:
Sadia Sarwar, Shafiq Ur Rahman, Jamshed Iqbal, Hafiz Saqib Ali, Muazzam Arif, Sumera Zaib, Humaira Nadeem, Mohsinul Mulk Bacha, Aqeel Imran
Publikováno v:
BMC Chemistry, Vol 15, Iss 1, Pp 1-15 (2021)
BMC Chemistry
BMC Chemistry
In diabetes, increased accumulation of sorbitol has been associated with diabetic complications through polyol pathway. Aldose reductase (AR) is one of the key factors involved in reduction of glucose to sorbitol, thereby its inhibition is important
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4accf2a6b9ff22aea144157ffa47ddee
https://doaj.org/article/4fa7feffe1c9431f8c8032e1bcd01492
https://doaj.org/article/4fa7feffe1c9431f8c8032e1bcd01492
Autor:
Iqra Hamid, Humaira Nadeem, Sameen Fatima Ansari, Sonia Khiljee, Inzamam Abbasi, Asma Bukhari, Muazzam Arif, Muhammad Imran
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 18(7)
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) are the commonly used therapeutic interventions of inflammation and pain that competitively inhibit the cyclooxygenase (COX) enzymes. Several side effects like gastrointestinal and renal toxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52815b3f28f938e32d2a7153b4d34ec9
https://pubmed.ncbi.nlm.nih.gov/34931968
https://pubmed.ncbi.nlm.nih.gov/34931968
Publikováno v:
BMC Chemistry, Vol 13, Iss 1, Pp 1-13 (2019)
BMC Chemistry
BMC Chemistry
Background Isoxazole is an important pharmacophore in medicinal chemistry with a wide range of pharmacological activities. The present study deals with the synthesis and evaluation of antinociceptive potential of nine novel 3-substituted-isoxazole-4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf1b182cdead4f4b044a9f6e10213c0
http://link.springer.com/article/10.1186/s13065-019-0518-6
http://link.springer.com/article/10.1186/s13065-019-0518-6
Autor:
Mohsinul Mulk Bacha, Nadeem, Humaira, Sumera Zaib, Sarwar, Sadia, Aqeel Imran, Rahman, Shafiq Ur, Ali, Hafiz Saqib, Muazzam Arif, Iqbal, Jamshed
Additional file 1: Figure S1. 2D interactions of cognate ligand (FX4401) (a), selective inhibitor (3e) of ALR1 (b) and dual inhibitors (c: 3f; d; 3g) inside the active pocket of 3FX4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140aadb0e1aeaa438939ed94c5fb977b
Autor:
Jamshed Iqbal, Humaira Nadeem, Shafiq Ur Rehman, Sadia Sarwar, Mohsinul Mulk Bacha, Sumera Zaib, Aqeel Imran, Hafiz Saqib Ali, Muazzam Arif
In diabetes, increased accumulation of sorbitol has been associated with diabetic complications through polyol pathway. Aldose reductase (AR) is one of the key factors involved in reduction of glucose to sorbitol, thereby its inhibition is considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d9850b4136ad7f01156f31df863af68
https://doi.org/10.21203/rs.3.rs-54676/v2
https://doi.org/10.21203/rs.3.rs-54676/v2
Autor:
Arif-ullah Khan, Muazzam Arif, Zulkifal Malik, Nadia Shamshad Malik, Muhammad Tariq Khan, Muzaffar Abbas, Ibrahim Javed, Humaira Nadeem
Publikováno v:
Drug development researchREFERENCES.
Benzimidazole is an important pharmacophore for clinically active drugs against inflammation and treatment of pain, however, it is associated with gastrointestinal side effects. Here we synthesized benzimidazole based agents with significant analgesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4b745860bf9e71eaee0377e8417d9e
https://pubmed.ncbi.nlm.nih.gov/32780491
https://pubmed.ncbi.nlm.nih.gov/32780491