Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Muamera Zulcic"'
Autor:
Shweta Joshi, Alok R Singh, Simon S Wong, Muamera Zulcic, Min Jiang, Annie Pardo, Moises Selman, James S Hagood, Donald L Durden
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182851 (2017)
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by cellular phenotype alterations and deposition of extracellular matrix proteins. The alternative activation of macrophages in the lungs has been associated as a major facto
Externí odkaz:
https://doaj.org/article/6c067b2716cc4e6b9d917aa70c083a3d
Autor:
Alok R Singh, Shweta Joshi, Muamera Zulcic, Michael Alcaraz, Joseph R Garlich, Guillermo A Morales, Yoon J Cho, Lei Bao, Michael L Levy, Robert Newbury, Denise Malicki, Karen Messer, John Crawford, Donald L Durden
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150836 (2016)
Sonic hedgehog (SHH) medulloblastoma (MB) subtype is driven by a proliferative CD15+ tumor propagating cell (TPC), also considered in the literature as a putative cancer stem cell (CSC). Despite considerable research, much of the biology of this TPC
Externí odkaz:
https://doaj.org/article/ac04ecf6d2174fb5897dca31ed3b2a60
Autor:
Shweta Joshi, Alok R Singh, Muamera Zulcic, Lei Bao, Karen Messer, Trey Ideker, Janusz Dutkowski, Donald L Durden
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95893 (2014)
Although it is well-established that the macrophage M1 to M2 transition plays a role in tumor progression, the molecular basis for this process remains incompletely understood. Herein, we demonstrate that the small GTPase, Rac2 controls macrophage M1
Externí odkaz:
https://doaj.org/article/08e8e75a1b884bac8e48ce04418eec24
Supplementary Figure Legend from A Macrophage-Dominant PI3K Isoform Controls Hypoxia-Induced HIF1α and HIF2α Stability and Tumor Growth, Angiogenesis, and Metastasis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4295afd77f35e423e479f11611130bb2
https://doi.org/10.1158/1541-7786.22514230.v1
https://doi.org/10.1158/1541-7786.22514230.v1
Autor:
Donald L. Durden, Joseph R. Garlich, Guillermo A. Morales, Christopher K. Glass, Hyun Bae Chun, Dylan Skola, Muamera Zulcic, Timothy V. Pham, Kevin X. Liu, Alok R. Singh, Shweta Joshi
File contains Supplementary Methods and References
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ed2e16625c34228c62d32c2d601d92
https://doi.org/10.1158/1535-7163.22506045
https://doi.org/10.1158/1535-7163.22506045
Autor:
Donald L. Durden, Joseph R. Garlich, Guillermo A. Morales, Christopher K. Glass, Hyun Bae Chun, Dylan Skola, Muamera Zulcic, Timothy V. Pham, Kevin X. Liu, Alok R. Singh, Shweta Joshi
Supplementary Fig. S1 shows JQ1 blocks IL4 induced CD206 expression. Supplementary Fig. S2 shows Differentially expressed genes in LPS-stimulated or IL4 stimulated BMDMs. Supplementary Fig. S3 shows Effect of JQ1 on LLC tumor growth. Supplementary Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2adac5ed436b48495ac221a346a90f80
https://doi.org/10.1158/1535-7163.22506042
https://doi.org/10.1158/1535-7163.22506042
Autor:
Catherine C. Hedrick, Muamera Zulcic, Shweta Joshi, P. Dominick Sanders, Timothy V. Pham, Huy Q. Dinh, Daniel Shiang, Pablo Tamayo, Andrew B. Sharabi, Dylan Skola, Donald L. Durden, Kevin X. Liu, Guillermo A. Morales, Joseph R. Garlich, Christopher K. Glass, Alok R. Singh
Publikováno v:
Mol Cancer Ther
Macrophages (MΦ) play a critical role in tumor growth, immunosuppression, and inhibition of adaptive immune responses in cancer. Hence, targeting signaling pathways in MΦs that promote tumor immunosuppression will provide therapeutic benefit. PI3K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17da35e94e2104d40ff81786bac46ce2
https://doi.org/10.1158/1535-7163.mct-19-0947
https://doi.org/10.1158/1535-7163.mct-19-0947
Autor:
Hyun B. Chun, Timothy V. Pham, Dylan Skola, Alok R. Singh, Donald L. Durden, Guillermo A. Morales, Muamera Zulcic, Christopher K. Glass, Kevin X. Liu, Joseph R. Garlich, Shweta Joshi
Publikováno v:
Molecular cancer therapeutics, vol 18, iss 6
Mol Cancer Ther
Mol Cancer Ther
Macrophages (MΘs) are key immune infiltrates in solid tumors and serve as major drivers behind tumor growth, immune suppression, and inhibition of adaptive immune responses in the tumor microenvironment (TME). Bromodomain and extraterminal (BET) pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a343d9a4c13a59d08289183cb7fcdd
https://escholarship.org/uc/item/7sj6f8cd
https://escholarship.org/uc/item/7sj6f8cd
Autor:
Annie Pardo, Donald L. Durden, Shweta Joshi, Simon S. Wong, Alok R. Singh, Moisés Selman, Min Jiang, James S. Hagood, Muamera Zulcic
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 8, p e0182851 (2017)
PLoS ONE, Vol 12, Iss 8, p e0182851 (2017)
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by cellular phenotype alterations and deposition of extracellular matrix proteins. The alternative activation of macrophages in the lungs has been associated as a major facto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe249134d11ae8f556fdeffe20f3bdf0
http://europepmc.org/articles/PMC5560537
http://europepmc.org/articles/PMC5560537
Autor:
Shweta Joshi, Kevin Liu, Muamera Zulcic, Alok Singh, Timothy Pham, Christopher K. Glass, Andrew Sharabi, Guillermo A. Morales, Joseph R. Garlich, Donald Durden
Publikováno v:
Cancer Research. 79:109-109
Introduction: Macrophages (MΘs) play important roles in the initiation and progression of solid tumors and in establishing an immunosuppressive tumor microenvironment (TME) that dampens effective anti-tumor immune responses in cancer. Hence, targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a0ef865ab5dcdc49ef28af029102edc
https://doi.org/10.1158/1538-7445.am2019-109
https://doi.org/10.1158/1538-7445.am2019-109