Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mu-Yang Huang"'
Autor:
Mu-Yang Huang, Yu-Chi Chen, Wen-Yu Lyu, Xin-Yu He, Zi-Han Ye, Can-Yu Huang, Xin-Ling He, Xiuping Chen, Xiaobing Chen, Baoxian Zhang, Guoyin Kai, Xiaolei Zhang, Ting Li, Mingqing Huang, Jin-Jian Lu
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 106988- (2023)
Profiting from the sustained clinical improvement and prolonged patient survival, immune checkpoint blockade of programmed cell death protein 1 (PD-1)/programmed death-ligand 1 (PD-L1) axis has emerged as a revolutionary cancer therapy approach. Howe
Externí odkaz:
https://doaj.org/article/461ae4df959e42b091b6d24486ab79eb
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 4, Pp 1467-1487 (2023)
Described as a “don't eat me” signal, CD47 becomes a vital immune checkpoint in cancer. Its interaction with signal regulatory protein alpha (SIRPα) prevents macrophage phagocytosis. In recent years, a growing body of evidences have unveiled tha
Externí odkaz:
https://doaj.org/article/94b32ce1d5114ddca6dd4402e2325dba
Autor:
Min-Xia Su, Yu-Lian Xu, Xiao-Ming Jiang, Mu-Yang Huang, Le-Le Zhang, Luo-Wei Yuan, Xiao-Huang Xu, Qi Zhu, Jian-Li Gao, Jia-Hong Lu, Xiuping Chen, Ming-Qing Huang, Yitao Wang, Jin-Jian Lu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 3, Pp 1240-1253 (2022)
The mammalian target of rapamycin (mTOR) pathway is abnormally activated in lung cancer. However, the anti-lung cancer effect of mTOR inhibitors as monotherapy is modest. Here, we identified that ginsenoside Rh2, an active component of Panax ginseng
Externí odkaz:
https://doaj.org/article/dc390603aa844426b73e68a3e9210154
Autor:
Yu‐Lian Xu, Luo‐Wei Yuan, Xiao‐Ming Jiang, Min‐Xia Su, Mu‐Yang Huang, Yu‐Chi Chen, Le‐Le Zhang, Xiuping Chen, Hong Zhu, Jin‐Jian Lu
Publikováno v:
MedComm, Vol 3, Iss 3, Pp n/a-n/a (2022)
Abstract Lung cancer is the leading cause of cancer death worldwide, of which lung adenocarcinoma (LUAD) is the most common subtype. Metastasis is the major cause of poor prognosis and mortality for lung cancer patients, which urgently needs great ef
Externí odkaz:
https://doaj.org/article/19de3db6b31944489e11f82262f5ba1f
Autor:
Zi-Han Ye, Xiao-Ming Jiang, Mu-Yang Huang, Yu-Lian Xu, Yu-Chi Chen, Luo-Wei Yuan, Can-Yu Huang, Wei-Bang Yu, Xiuping Chen, Jin-Jian Lu
Publikováno v:
Translational Oncology, Vol 14, Iss 9, Pp 101162- (2021)
The anti-phagocytosis signal, CD47, prevents phagocytosis when it interacts with signal-regulatory protein alpha (SIRPα) on macrophages. Given the vital role of CD47 in immune response, further investigation on the regulation of CD47 in tumor microe
Externí odkaz:
https://doaj.org/article/4bd8fe6000854940a31db4ecffc750f3
Publikováno v:
Translational Oncology, Vol 13, Iss 12, Pp 100862- (2020)
CD47 is overexpressed in various types of cancers and it can directly bind with SIRPα, which is mainly located on macrophages. The binding of CD47-SIRPα transmits a “don't eat me” signal, which can prevent cancer cells from immune clearance. Ta
Externí odkaz:
https://doaj.org/article/4f6dfbf393094fc8902c97a23086bc63
Publikováno v:
Chinese Medicine, Vol 13, Iss 1, Pp 1-9 (2018)
Abstract Cancer is still presenting a serious threat to human health worldwide. The understanding of the complex biology of cancer and the development of oncotherapy have led to increasing treatment approaches such as targeted therapy and immunothera
Externí odkaz:
https://doaj.org/article/bee01c7619c8430daabbb995f58a7910
Autor:
Jin-Jian Lu, Mingqing Huang, Jian-Li Gao, Xiao-Ming Jiang, Xiao-Huang Xu, Jia-Hong Lu, Qi Zhu, Yu-Lian Xu, Mu-Yang Huang, Min-Xia Su, Le-Le Zhang, Yitao Wang, Luo-Wei Yuan, Xiuping Chen
Publikováno v:
Acta Pharmaceutica Sinica B. 12:1240-1253
The mammalian target of rapamycin (mTOR) pathway is abnormally activated in lung cancer. However, the anti-lung cancer effect of mTOR inhibitors as monotherapy is modest. Here, we identified that ginsenoside Rh2, an active component of Panax ginseng
Publikováno v:
Physica A: Statistical Mechanics and its Applications. 618:128692
Publikováno v:
Europhysics Letters. 142:41002
In this paper, coupled-phase oscillator chains with localized many-body interactions are studied. Systems have rich patterns such as chimera and twisted states. The coupled-phase oscillator chains have long-range two-body interactions and short-range