Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mu-Wen Chen"'
Autor:
Jia-Bing Li, Xiao-Yu Hu, Mu-Wen Chen, Cai-Hong Xiong, Na Zhao, Yan-Hui Ge, Hao Wang, Xiao-Ling Gao, Nan-Jie Xu, Lan-Xue Zhao, Zhi-Hua Yu, Hong-Zhuan Chen, Yu Qiu
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-18 (2023)
Abstract Background Ribosomal protein S6 kinase 1 (S6K1) is a serine–threonine kinase that has two main isoforms: p70S6K (70-kDa isoform) and p85S6K (85-kDa isoform). p70S6K, with its upstream mammalian target of rapamycin (mTOR), has been shown to
Externí odkaz:
https://doaj.org/article/7a4fe3561f9847d4b6ecb9f8834498b3
Publikováno v:
Neuroscience. 408:239-247
M1 muscarinic receptors have long been identified as a potential therapeutic target for the treatment of cognitive impairment in Alzheimer's disease (AD). Our previous study has shown that M1 receptors promote membrane insertion and synaptic delivery
Autor:
Ling Tang, Yu Qiu, Ying-Hui Yan, Lan-Xue Zhao, Cai-Hong Xiong, Hong-Zhuan Chen, Mu-Wen Chen, Ming-Gang Liu
Publikováno v:
Neuropharmacology. 146:242-251
Cognitive flexibility is an important aspect of executive function. The cholinergic system, an important component of cognition, has been shown to modulate cognitive flexibility mainly through the striatum and prefrontal cortex. The role of M1 muscar
Publikováno v:
Cellular and molecular neurobiology. 40(4)
M1 muscarinic acetylcholine receptors (M1 mAChRs) have long been an attractive target for the treatment of Alzheimer's disease (AD), the most common cause of dementia in the elderly. M1 mAChR agonists show desirably preclinical activities; however, m