Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Mu Gao"'
Autor:
Troy von Beck, Karla Navarrete, Nicholas A. Arce, Mu Gao, Gordon A. Dale, Meredith E. Davis-Gardner, Katharine Floyd, Luis Mena Hernandez, Nikita Mullick, Abigail Vanderheiden, Ioanna Skountzou, Suresh V. Kuchipudi, Rathi Saravanan, Renhao Li, Jeffrey Skolnick, Mehul S. Suthar, Joshy Jacob
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses a clear threat to humanity. It has infected over 200 million and killed 4 million people worldwide, and infections continue with no end in sight. To control the pandemic,
Externí odkaz:
https://doaj.org/article/e02836828324427c886174a79b6c8fa8
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Accurate descriptions of protein-protein interactions are essential for understanding biological systems. Here the authors present AF2Complex and show that application to the E. coli cytochrome biogenesis system I yields confident computational model
Externí odkaz:
https://doaj.org/article/292112ae49f04dfdb35777d29f8cb011
Publikováno v:
eLife, Vol 11 (2022)
To reach their final destinations, outer membrane proteins (OMPs) of gram-negative bacteria undertake an eventful journey beginning in the cytosol. Multiple molecular machines, chaperones, proteases, and other enzymes facilitate the translocation and
Externí odkaz:
https://doaj.org/article/97c6484d891040a4b954c311f162650c
Publikováno v:
Materials, Vol 16, Iss 6, p 2208 (2023)
Titanium-tantalum (Ti-Ta) alloy has excellent biomechanical properties with high strength and low Young’s modulus, showing great application potential in the biomedical industry. In this study, Ti-Ta alloy samples were prepared by laser powder bed
Externí odkaz:
https://doaj.org/article/70311fa362ac4763aa650f619c058973
Autor:
Peter M. Eimon, Mostafa Ghannad-Rezaie, Gianluca De Rienzo, Amin Allalou, Yuelong Wu, Mu Gao, Ambrish Roy, Jeffrey Skolnick, Mehmet Fatih Yanik
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
One challenge in drug screening for neurological disorders is how to accurately capture disease pathology and side effects. Here, the authors developed a multi-channel recording platform based on a zebrafish genetic model of epilepsy to screen for an
Externí odkaz:
https://doaj.org/article/ca48ead3c4314e8da4bd2a2868831cfd
Autor:
Chunlai Gao, Kunyuan Gao, Yusheng Ding, Haonan Li, Xiaolan Wu, Shengping Wen, Mu Gao, Hui Huang, Zuoren Nie, Dejing Zhou
Publikováno v:
Metals, Vol 11, Iss 5, p 759 (2021)
The thermodynamics of five Al3Er compounds were investigated through first-principles density-functional theory (DFT) and experimental analysis. The Al3Er compounds with Al3Ho.hR20 (prototype Al3Ho, Pearson symbol hR20), Cu3Au.cP4, AlNd3.hP8, Ni3Ti.h
Externí odkaz:
https://doaj.org/article/8ca6acf800c44ac48cf042acfe570f4b
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0196849 (2018)
To exploit the plethora of information provided by Next Generation Sequencing, the identification of the genetic mutations responsible for disease in general or cancer in particular, among the thousands of neutral germline or somatic variations is a
Externí odkaz:
https://doaj.org/article/d2e1d88f930540a6950035f82fd960a4
Publikováno v:
F1000Research, Vol 5 (2016)
Native proteins perform an amazing variety of biochemical functions, including enzymatic catalysis, and can engage in protein-protein and protein-DNA interactions that are essential for life. A key question is how special are these functional propert
Externí odkaz:
https://doaj.org/article/60e4cab3e8f74f56b1fb0508443d8256
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150965 (2016)
The advance of next-generation sequencing technologies has made exome sequencing rapid and relatively inexpensive. A major application of exome sequencing is the identification of genetic variations likely to cause Mendelian diseases. This requires p
Externí odkaz:
https://doaj.org/article/7ac9b643bcc6491fa6a4f6bcadd51c08
Autor:
Mu Gao, Jeffrey Skolnick
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 10, p e1003302 (2013)
Many biological activities originate from interactions between small-molecule ligands and their protein targets. A detailed structural and physico-chemical characterization of these interactions could significantly deepen our understanding of protein
Externí odkaz:
https://doaj.org/article/488bd90c05274c05a7ec9b1c56118864