Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin

Autor: Gately S, Twardowski P, Ms, Stack, Patrick M, Boggio L, Dl, Cundiff, Hw, Schnaper, Madison L, Volpert O, Bouck N, Jan Johannes Enghild, Hc, Kwaan, Ga, Soff

Publikováno v: Gately, S, Twardowski, P, Stack, M S, Patrick, M, Boggio, L, Cundiff, D L, Schnaper, H W, Madison, L, Volpert, O, Bouck, N, Enghild, J, Kwaan, H C & Soff, G A 1996, ' Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin ', Cancer Research, vol. 56, no. 21, pp. 4887-90 .
Scopus-Elsevier
Europe PubMed Central

Udgivelsesdato: 1996-Nov-1 Angiostatin is an inhibitor of angiogenesis and metastatic growth that is found in tumor-bearing animals and can be generated in vitro by the proteolytic cleavage of plasminogen. The mechanism by which angiostatin is produc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3d4e56783d801d3493215f9517926b69
https://pure.au.dk/portal/da/publications/human-prostate-carcinoma-cells-express-enzymatic-activity-that-converts-human-plasminogen-to-the-angiogenesis-inhibitor-angiostatin(3d7d8a90-8656-11dd-a5a8-000ea68e967b).html

Combination non-targeted and sGRP78-targeted nanoparticle drug delivery outperforms either component to treat metastatic ovarian cancer.

Autor: Sjoerdsma JN; Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA., Bromley EK; Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA., Shin J; Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA., Hilliard T; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Liu Y; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Horgan C; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Hwang G; Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA., Bektas M; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Omstead D; Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Kiziltepe T; Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA., Stack MS; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA. Electronic address: Sharon.Stack.11@nd.edu., Bilgicer B; Department of Chemical & Biomolecular Engineering, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Berthiaume Institute for Precision Health, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA; Center for Rare & Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA. Electronic address: BBilgicer@nd.edu.

Publikováno v: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2024 Nov; Vol. 375, pp. 438-453. Date of Electronic Publication: 2024 Sep 19.

Gender- and Age-Based Characterization and Comparison of the Murine Primary Peritoneal Mesothelial Cell Proteome.

Autor: Wang Z; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN 46556.; Harper Cancer Research Institute, University of Notre Dame, South Bend IN 46617., Liu Y; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN 46556.; Harper Cancer Research Institute, University of Notre Dame, South Bend IN 46617., Safavisohi R; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN 46556.; Harper Cancer Research Institute, University of Notre Dame, South Bend IN 46617., Asem M; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN 46556.; Harper Cancer Research Institute, University of Notre Dame, South Bend IN 46617., Hu DD; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN 46556., Stack MS; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN 46556.; Harper Cancer Research Institute, University of Notre Dame, South Bend IN 46617., Champion MM; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame IN 46556.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Oct 11. Date of Electronic Publication: 2024 Oct 11.

Neutrophils resist ferroptosis and promote breast cancer metastasis through aconitate decarboxylase 1.

Autor: Zhao Y; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Liu Z; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Liu G; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Integrated Biomedical Sciences Graduate Program, University of Notre Dame, Notre Dame, IN 46556, USA., Zhang Y; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Integrated Biomedical Sciences Graduate Program, University of Notre Dame, Notre Dame, IN 46556, USA., Liu S; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Gan D; Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN 46556, USA., Chang W; Department of Medical and Molecular Genetics and Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Electrical and Computer Engineering, Purdue University, Indianapolis, IN 46202, USA., Peng X; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Sung ES; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Gilbert K; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Zhu Y; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Integrated Biomedical Sciences Graduate Program, University of Notre Dame, Notre Dame, IN 46556, USA., Wang X; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Zeng Z; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Baldwin H; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Ren G; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Weaver J; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Huron A; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Mayberry T; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Wang Q; Division of Hematology/Oncology, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA., Wang Y; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA., Diaz-Rubio ME; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA., Su X; Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08901, USA; Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ 08901, USA., Stack MS; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Zhang S; Department of Pathology, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, TX 75235, USA., Lu X; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA., Sheldon RD; Mass Spectrometry Core, Van Andel Institute, Grand Rapids, MI, USA., Li J; Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN 46556, USA., Zhang C; Department of Medical and Molecular Genetics and Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202, USA; Department of Electrical and Computer Engineering, Purdue University, Indianapolis, IN 46202, USA., Wan J; Department of Applied and Computational Mathematics and Statistics, University of Notre Dame, Notre Dame, IN 46556, USA; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202, USA; School of Informatics and Computing, Indiana University - Purdue University at Indianapolis, Indianapolis, IN 46202, USA., Lu X; Department of Biological Sciences, Boler-Parseghian Center for Rare and Neglected Diseases, University of Notre Dame, Notre Dame, IN 46556, USA; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46556, USA; Integrated Biomedical Sciences Graduate Program, University of Notre Dame, Notre Dame, IN 46556, USA; Tumor Microenvironment and Metastasis Program, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, IN 46202, USA. Electronic address: xlu@nd.edu.

Publikováno v: Cell metabolism [Cell Metab] 2023 Oct 03; Vol. 35 (10), pp. 1688-1703.e10.

Advanced Glycation End Products as a Potential Target for Restructuring the Ovarian Cancer Microenvironment: A Pilot Study.

Autor: Harper EI; Integrated Biomedical Sciences Graduate Program, University of Notre Dame, Notre Dame, IN 46556, USA.; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA., Siroky MD; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA., Hilliard TS; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA., Dominique GM; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA., Hammond C; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA., Liu Y; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA., Yang J; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA., Hubble VB; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Walsh DJ; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Melander RJ; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Melander C; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA., Ravosa MJ; Center for Functional Anatomy and Evolution, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Stack MS; Department of Chemistry & Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.; Harper Cancer Research Institute, University of Notre Dame, Notre Dame, IN 46617, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 06; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 06.