Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mrunal A. Jaywant"'
Autor:
Joerg Schlingemann, Michael J. Burns, David J. Ponting, Carolina Martins Avila, Naiffer E. Romero, Mrunal A. Jaywant, Graham F. Smith, Ian W. Ashworth, Stephanie Simon, Christoph Saal, Andrzej Wilk
Publikováno v:
Journal of Pharmaceutical Sciences. 112:1287-1304
This article reports the outcome of an in silico analysis of more than 12,000 small molecule drugs and drug impurities, identifying the nitrosatable structures, assessing their potential to form nitrosamines under relevant conditions and the challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da45a3df822dccf8629262f20bfad6a7
https://doi.org/10.1016/j.xphs.2022.11.013
https://doi.org/10.1016/j.xphs.2022.11.013
Publikováno v:
Journal of Pharmaceutical Sciences. 112:1225-1230
Nitrosamines, the probable carcinogens have been reported with Angiotensin II Receptor Blocker (ARB) drugs, Ranitidine, and other medicines. Solvents play a vital role in the pharmaceutical industry in the separation, purification, and cleaning proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a7162c3f441ad6015e5f310afe5afa4
https://doi.org/10.1016/j.xphs.2022.11.024
https://doi.org/10.1016/j.xphs.2022.11.024
Autor:
Ch. Krishnam Raju, Sameer G. Navalgund, Avadhesh Kumar Pandey, Arunima Pola, Kaushik Ghosh, P Sanath Kumar Goud, S Gururaj, Mrunal A. Jaywant
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 140:1-10
Forced degradation of Doxofylline (DFL) in different stress (base and peroxide) conditions gave rise to two potential unknown impurities. These unknown degradation products DFL DEG-I and DFL DEG-II were evaluated using a new-reverse-phase high perfor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9501b4d03ab1013a3bcdafbcdae5283
https://doi.org/10.1016/j.jpba.2017.02.044
https://doi.org/10.1016/j.jpba.2017.02.044