Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mridula Dwivedi"'
Autor:
Ingrid R. Vetter, Dale Corkery, Luca Laraia, Nelli Erwin, Herbert Waldmann, Maja Köhn, Pablo Rios-Munoz, Roland Winter, Mridula Dwivedi, Walter Hofer, Lei Li, Yao-Wen Wu, Malte Metz, Beate Schölermann, Andreas Brockmeyer, Laura Klewer, Alexandra Friese, Petra Janning, Hacer Karatas, Georgios Konstantinidis, Slava Ziegler
Publikováno v:
Nature Chemical Biology
Laraia, L, Friese, A, Corkery, D P, Konstantinidis, G, Erwin, N, Hofer, W, Karatas, H, Klewer, L, Brockmeyer, A, Metz, M, Schölermann, B, Dwivedi, M, Li, L, Rios-Munoz, P, Köhn, M, Winter, R, Vetter, I R, Ziegler, S, Janning, P, Wu, Y W & Waldmann, H 2019, ' The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis ', Nature Chemical Biology, vol. 15, no. 7, pp. 710-720 . https://doi.org/10.1038/s41589-019-0307-5
Laraia, L, Friese, A, Corkery, D P, Konstantinidis, G, Erwin, N, Hofer, W, Karatas, H, Klewer, L, Brockmeyer, A, Metz, M, Schölermann, B, Dwivedi, M, Li, L, Rios-Munoz, P, Köhn, M, Winter, R, Vetter, I R, Ziegler, S, Janning, P, Wu, Y W & Waldmann, H 2019, ' The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis ', Nature Chemical Biology, vol. 15, no. 7, pp. 710-720 . https://doi.org/10.1038/s41589-019-0307-5
Autophagy mediates the degradation of damaged proteins, organelles and pathogens, and plays a key role in health and disease. Thus, the identification of new mechanisms involved in the regulation of autophagy is of major interest. In particular, litt
Publikováno v:
ChemBioChem. 20:1190-1195
Signaling of N-Ras and K-Ras4B proteins depends strongly on their correct localization in the cell membrane. In vivo studies suggest that intermolecular interactions foster the self-association of both N-Ras and K-Ras4B and the formation of nanoclust
Autor:
Janine Schulte-Zweckel, Mridula Dwivedi, Petra Janning, Andreas Brockmeyer, Roland Winter, Gemma Triola
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Reversible S-palmitoylation is a key regulatory mechanism of protein function and localization. There is increasing evidence that S-acylation is not restricted to palmitate but it includes shorter, longer, and unsaturated fatty acids. However, the di
Autor:
Florian Kreppel, Janis A. Müller, Jens von Einem, Tatjana Weil, Elsa Sanchez-Garcia, Clarissa Read, Sina Lippold, Gal Bitan, Christina M. Stürzel, Thomas Schrader, Michael Ehrmann, Marco Hebel, Frank-Gerrit Klärner, Roland Winter, Paul Bates, Mridula Dwivedi, Andrea Sowislok, Tanja Weil, Annika Röcker, Jan Münch, Rüdiger Groß, Konstantin M. J. Sparrer, Lukas Wettstein, Yasser B. Ruiz-Blanco, Paul Walther, Kenny Bravo-Rodriguez, My Hue Le, James Shorter, Nelli Erwin, Mirja Harms, Stephen M. Bart, Christian Heid
Publikováno v:
Journal of the American Chemical Society, vol 142, iss 40
Journal of the American Chemical Society
Journal of the American Chemical Society
Broad-spectrum antivirals are powerful weapons against dangerous viruses where no specific therapy exists, as in the case of the ongoing SARS-CoV-2 pandemic. We discovered that a lysine- and arginine-specific supramolecular ligand (CLR01) destroys en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946cf9bab288e137126d44b6bb9cf2e0
https://escholarship.org/uc/item/3049q3fv
https://escholarship.org/uc/item/3049q3fv
Publikováno v:
International journal of pharmaceutics. 591
Two of the most widely used surfactants to stabilize biologicals against e.g. interfacial stress are polysorbate 20 (PS20) and polysorbate 80 (PS80). In recent years, polysorbate degradation in biopharmaceutical formulations has been observed. Polyso
Autor:
Rainer Kassenböhmer, Martin Körsgen, Bonnie J. Tyler, Hans-Joachim Galla, Mridula Dwivedi, Heinrich F. Arlinghaus, Marcel Heeger
Publikováno v:
Langmuir. 34:8750-8757
Artificial lipid membranes play a growing role in technical applications such as biosensors in pharmacological research and as model systems in the investigation of biological lipid films. In the standard procedure for displaying the distribution of
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1860:1008-1014
Ras proteins are oncoproteins which play a pivotal role in cellular signaling pathways. All Ras proteins' signaling strongly depends on their correct localization in the cell membrane. Over 30% of cancers are driven by mutant Ras proteins, and KRas4B
Publikováno v:
European Journal of Pharmaceutical Sciences. 144:105211
Polysorbate is one of the most commonly employed non-ionic surfactant in protein containing biological formulations, whereby, it can stabilize these biomolecules under different stress conditions. Despite the fact that polysorbates are present in alm
Publikováno v:
International journal of pharmaceutics. 552(1-2)
Biotherapeutic protein formulations are often high concentration liquid protein solutions, which are required to be stable under pharmaceutically relevant storage conditions and presence of external stress. Non-ionic detergents like polysorbate have
Publikováno v:
Chembiochem : a European journal of chemical biology. 19(14)
Plasma membrane localization of myristoylated c-Src, a proto-oncogene protein-tyrosine kinase, is required for its signaling activity. Recent studies proposed that UNC119 protein functions as a solubilizing factor for myristoylated proteins, thereby