Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Mrízová, Iveta"'
Autor:
Mrízová, Iveta
6 Abstract Ellipticine (5,11-dimethyl-6H-pyrido[4,3-b]carbazole), an alkaloid isolated from Apocynaceae plants, exhibits significant antitumor and HIV activity. This antitumor agent binds to DNA and forms covalent DNA adducts. Enzymes, which are invo
Externí odkaz:
http://www.nusl.cz/ntk/nusl-353595
Autor:
Reed, Lindsay, Indra, Radek, Mrizova, Iveta, Moserova, Michaela, Schmeiser, Heinz H., Wolf, C. Roland, Henderson, Colin J., Stiborova, Marie, Phillips, David H., Arlt, Volker M.
Publikováno v:
In Toxicology and Applied Pharmacology 1 March 2019 366:64-74
Autor:
Willis, Alexandra J., Indra, Radek, Wohak, Laura E., Sozeri, Osman, Feser, Kerstin, Mrizova, Iveta, Phillips, David H., Stiborova, Marie, Arlt, Volker M.
Publikováno v:
In Toxicology 1 April 2018 398-399:1-12
Autor:
Stiborova, Marie, Poljakova, Jitka, Mrizova, Iveta, Borek-Dohalska, Lucie, Eckschlager, Tomas, Adam, Vojtech, Kizek, Rene, Frei, Eva
Publikováno v:
In International Journal of Electrochemical Science October 2014 9(10):5675-5689
Akademický článek
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Autor:
Mrízová, Iveta, Moserová, Michaela, Milichovský, Jan, Šulc, Miroslav, Kizek, René, Kubáčková, Kateřina, Arlt, Volker M., Stiborová, Marie
Publikováno v:
Mrízová, I, Moserová, M, Milichovský, J, Šulc, M, Kizek, R, Kubáčková, K, Arlt, V M & Stiborová, M 2016, ' Heterologous expression of human cytochrome P450 2S1 in Escherichia coli and investigation of its role in metabolism of benzo[a]pyrene and ellipticine ', Monatshefte für Chemie-Chemical Monthly, vol. 147, no. 5, pp. 881–888 . https://doi.org/10.1007/s00706-016-1738-2
Cytochrome P450 (CYP) 2S1 is “orphan” CYP that is overexpressed in several epithelial tissues and many human tumors. The pure enzyme is required for better understanding of its biological functions. Therefore, human CYP2S1 was considered to be pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d23e5923f453b19f82fe7a73d467e1ab
https://kclpure.kcl.ac.uk/en/publications/4b0f23ea-a26e-4baa-9582-0b41bec268e7
https://kclpure.kcl.ac.uk/en/publications/4b0f23ea-a26e-4baa-9582-0b41bec268e7
Autor:
Stiborová, Marie, Moserová, Michaela, Mrízová, Iveta, Dračínská, Helena, Martínek, Václav, Indra, Radek, Frei, Eva, Adam, Vojtěch, Kizek, René, Schmeiser, Heinz H., Kubáčková, Kateřina, Arlt, Volker M.
Publikováno v:
Stiborová, M, Moserová, M, Mrízová, I, Dračínská, H, Martínek, V, Indra, R, Frei, E, Adam, V, Kizek, R, Schmeiser, H H, Kubáčková, K & Arlt, V M 2016, ' Induced expression of microsomal cytochrome b 5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I) ', Monatshefte für Chemie-Chemical Monthly, vol. 147, pp. 897-904 . https://doi.org/10.1007/s00706-015-1636-z
The microsomal protein cytochrome b5, which is located in the membrane of the endoplasmic reticulum, has been shown to modulate many reactions catalyzed by cytochrome P450 (CYP) enzymes. We investigated the influence of exposure to the anticancer dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2761::5cdec6ce3b03f93ae09ccc350be5c5e1
https://kclpure.kcl.ac.uk/en/publications/57d15b99-82a2-47e6-800f-c25c9fe16476
https://kclpure.kcl.ac.uk/en/publications/57d15b99-82a2-47e6-800f-c25c9fe16476
Autor:
Mrízová, Iveta
6 Abstract Ellipticine (5,11-dimethyl-6H-pyrido[4,3-b]carbazole), an alkaloid isolated from Apocynaceae plants, exhibits significant antitumor and HIV activity. This antitumor agent binds to DNA and forms covalent DNA adducts. Enzymes, which are invo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::5a5ef066b61bc34b47487f93e754230b
http://www.nusl.cz/ntk/nusl-353595
http://www.nusl.cz/ntk/nusl-353595
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Mrízová, Iveta
Ellipticine is an alkaloid isolated from Apocynaceae plants exhibiting significant antitumor and anti-HIV activities. Cytochromes P450 (CYP) and peroxidases are the enzymes participating in metabolism of ellipticine. This process provides activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0c7cf3349cfa59e75bff9cc6f7f67007
http://www.nusl.cz/ntk/nusl-336069
http://www.nusl.cz/ntk/nusl-336069