Zobrazeno 1 - 10
of 214
pro vyhledávání: '"MprF"'
Autor:
Yanlei Xu, Yanghua Xiao, Huilin Zhao, Bingjie Wang, Jingyi Yu, Yongpeng Shang, Ying Zhou, Xiaocui Wu, Yinjuan Guo, Fangyou Yu
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundDaptomycin non-susceptible Staphylococcus aureus (DNS) strains pose a serious clinical threat, yet their characteristics remain poorly understood.MethodsDNS derivatives were generated by exposing S. aureus strains to subinhibitory concentra
Externí odkaz:
https://doaj.org/article/5b8ffab5cab44b658c00d06e2bffda32
Autor:
Christian D. Freeman, Tayte Hansen, Ramona Urbauer, Brian J. Wilkinson, Vineet K. Singh, Kelly M. Hines
Publikováno v:
mSphere, Vol 9, Iss 6 (2024)
ABSTRACT Daptomycin is a membrane-targeting last-resort antimicrobial therapeutic for the treatment of infections caused by methicillin- and/or vancomycin-resistant Staphylococcus aureus. In the rare event of failed daptomycin therapy, the source of
Externí odkaz:
https://doaj.org/article/2bb97e6d17eb40cd96a750ff86b94758
Autor:
Francesca Boldrin, Laura Cioetto Mazzabò, Marie-Antoinette Lanéelle, Laura Rindi, Greta Segafreddo, Anne Lemassu, Gilles Etienne, Marta Conflitti, Mamadou Daffé, Alfredo Garzino Demo, Riccardo Manganelli, Hedia Marrakchi, Roberta Provvedi
Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Aminoacyl-phosphatidylglycerol (aaPG) synthases are bacterial enzymes that usually catalyze transfer of aminoacyl residues to the plasma membrane phospholipid phosphatidylglycerol (PG). The result is introduction of positive charg
Externí odkaz:
https://doaj.org/article/32285889bf644d34b70fbdc0a7797550
Autor:
Adeline Boutet-Dubois, Chloé Magnan, Alexi Lienard, Cassandra Pouget, Flavien Bouchet, Hélène Marchandin, Romaric Larcher, Jean-Philippe Lavigne, Alix Pantel
Publikováno v:
Antibiotics, Vol 12, Iss 12, p 1647 (2023)
Daptomycin (DAP) represents an interesting alternative to treat methicillin-resistant Staphylococcus aureus (MRSA) infections. Different mechanisms of DAP resistance have been described; however, in vivo-acquired resistance is uncharacterized. This s
Externí odkaz:
https://doaj.org/article/dae782fe258b4ed386c4abc4737cf354
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Gram-positive bacterial cells are protected from the environment by a cell envelope that is comprised of a thick layer of peptidoglycan that maintains cell shape and teichoic acid polymers whose biological function remains unclear. In Bacill
Externí odkaz:
https://doaj.org/article/2400a4277e4e48808f179f1daf49f8ff
Autor:
Rafi Rashid, Zeus Jaren Nair, Dominic Ming Hao Chia, Kelvin Kian Long Chong, Amaury Cazenave Gassiot, Stewart A. Morley, Doug K. Allen, Swaine L. Chen, Shu Sin Chng, Markus R. Wenk, Kimberly A. Kline
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT The bacterial cell membrane is an interface for cell envelope synthesis, protein secretion, virulence factor assembly, and a target for host cationic antimicrobial peptides (CAMPs). To resist CAMP killing, several Gram-positive pathogens enc
Externí odkaz:
https://doaj.org/article/32be3af729934681ae993b200c2266d8
Akademický článek
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Autor:
Maarten Goedseels, Chris W. Michiels
Publikováno v:
Microorganisms, Vol 11, Iss 8, p 2024 (2023)
Hop beta acids (HBAs) are characteristic compounds from the hop plant that are of interest for their strong antimicrobial activity. In this work, we report a resistance mechanism against HBA in the foodborne pathogen Listeria monocytogenes. Using an
Externí odkaz:
https://doaj.org/article/42d50f0520354e6a8330c6abf403a029
Autor:
Christoph J Slavetinsky, Janna N Hauser, Cordula Gekeler, Jessica Slavetinsky, André Geyer, Alexandra Kraus, Doris Heilingbrunner, Samuel Wagner, Michael Tesar, Bernhard Krismer, Sebastian Kuhn, Christoph M Ernst, Andreas Peschel
Publikováno v:
eLife, Vol 11 (2022)
The pandemic of antibiotic resistance represents a major human health threat demanding new antimicrobial strategies. Multiple peptide resistance factor (MprF) is the synthase and flippase of the phospholipid lysyl-phosphatidylglycerol that increases
Externí odkaz:
https://doaj.org/article/cf8b010f11b840a988723d76c0335377
Akademický článek
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