Pulmonary inflammation is a feature of human and murine schistosomiasis, promoted by type-2 dendritic cells

Autor: Houlder, Emma, Costain, Alice, Nambuya, Irene, Brown, Sheila, Koopman, J. P. R., Langenberg, M. C. C., Janse, J. J., Hoogerwerf, M. A., Ridley, A. J. L., Forde-Thomas, J. E., Colombo, Stefano, Winkel, B. M. F., Galdon, Alicia, Hoffmann, K. F., Cook, Peter, Roestenberg, M., Mpairwe, H., MacDonald, Andrew

Publikováno v: Houlder, E, Costain, A, Nambuya, I, Brown, S, Koopman, J P R, Langenberg, M C C, Janse, J J, Hoogerwerf, M A, Ridley, A J L, Forde-Thomas, J E, Colombo, S, Winkel, B M F, Galdon, A, Hoffmann, K F, Cook, P, Roestenberg, M, Mpairwe, H & MacDonald, A 2023, ' Pulmonary inflammation is a feature of human and murine schistosomiasis, promoted by type-2 dendritic cells ', Nature Communications, vol. 14, no. 1, 1863 . https://doi.org/10.1038/s41467-023-37502-z

Schistosomiasis is a parasitic disease affecting over 200 million people in multiple organs, including the lungs. Despite this, there is little understanding of pulmonary immune responses during schistosomiasis. Here, we show type-2 dominated lung im

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https://research.manchester.ac.uk/en/publications/ba35e56c-c0f9-476e-a9a2-0eb28049eaac

Asthma inflammatory phenotypes on four continents: most asthma is non-eosinophilic

Autor: Pembrey, L, Brooks, C, Mpairwe, H, Figueiredo, CA, Oviedo, AY, Chico, M, Ali, H, Nambuya, I, Tumwesige, P, Robertson, S, Rutter, CE, van Veldhoven, K, Ring, S, Barreto, ML, Cooper, PJ, Henderson, J, Cruz, AA, Douwes, J, Pearce, N, WASP Study Group

BACKGROUND: Most studies assessing pathophysiological heterogeneity in asthma have been conducted in high-income countries (HICs), with little known about the prevalence and characteristics of different asthma inflammatory phenotypes in low-and middl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::bed87f83c7a303c9236f75a2aa462b9d
https://openaccess.sgul.ac.uk/id/eprint/114828/1/dyac173.pdf

Asthma inflammatory phenotypes on four continents: most asthma is non-eosinophilic.

Autor: Pembrey L; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK., Brooks C; Centre for Public Health Research, Massey University, Wellington, New Zealand., Mpairwe H; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Figueiredo CA; Institute of Collective Health, Federal University of Bahia, Salvador, Brazil., Oviedo AY; Fundacion Ecuatoriana Para Investigacion en Salud, Quito, Ecuador., Chico M; Fundacion Ecuatoriana Para Investigacion en Salud, Quito, Ecuador., Ali H; Centre for Public Health Research, Massey University, Wellington, New Zealand., Nambuya I; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Tumwesige P; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Robertson S; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK., Rutter CE; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK., van Veldhoven K; Department of Non-communicable Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK., Ring S; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; MRC Integrative Epidemiology Unit at University of Bristol, Bristol, UK., Barreto ML; Institute of Collective Health, Federal University of Bahia, Salvador, Brazil.; Center for Data and Knowledge Integration for Health (CIDACS), Fiocruz, Bahia, Brazil., Cooper PJ; Fundacion Ecuatoriana Para Investigacion en Salud, Quito, Ecuador.; School of Medicine, Universidad Internacional del Ecuador, Quito, Ecuador.; Institute of Infection and Immunity, St George's University of London, London, UK., Henderson J; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Cruz AA; ProAR, Federal University of Bahia, Salvador, Brazil.; Institute for Health Sciences, Federal University of Bahia, Salvador, Brazil., Douwes J; Centre for Public Health Research, Massey University, Wellington, New Zealand., Pearce N; Department of Medical Statistics, London School of Hygiene & Tropical Medicine, London, UK.; Centre for Public Health Research, Massey University, Wellington, New Zealand.

Publikováno v: International journal of epidemiology [Int J Epidemiol] 2023 Apr 19; Vol. 52 (2), pp. 611-623.

Prevalence and correlates of neurocognitive impairment and psychiatric disorders among schoolchildren in Wakiso District, Uganda: a cross-sectional study.

Autor: Nampijja M; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; Maternal and Child Wellbeing Unit, African Population and Health Research Center, Nairobi, Kenya., Sembajjwe W; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda., Mpairwe H; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; London School of Hygiene and Tropical Medicine, Keppel Street, Bloomsbury, London, London, WC1E 7HT, UK., UK., Mpango R; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Mental Health, School of Health Sciences, Soroti University, Soroti, Uganda., Kinyanda E; MRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.; Department of Psychiatry, College of Health Sciences, Makerere University, Kampala,, Kampala, P.O. Box 7072, Kampala, Uganda.

Publikováno v: Wellcome open research [Wellcome Open Res] 2022 Dec 07; Vol. 6, pp. 217. Date of Electronic Publication: 2022 Dec 07 (Print Publication: 2021).

Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration

Autor: Pembrey, L, Barreto, ML, Douwes, J, Cooper, P, Henderson, J, Mpairwe, H, Ardura-Garcia, C, Chico, M, Brooks, C, Cruz, AA, Elliott, AM, Figueiredo, CA, Langan, SM, Nassanga, B, Ring, S, Rodrigues, L, Pearce, N

Publikováno v: ERJ Open Research
Pembrey, L, Barreto, M, Douwes, J, Cooper, P, Henderson, J, Mpairwe, H, Ardura-Garcia, C, Chico, M, Brooks, C, Cruz, A, Elliott, A M, Figueiredo, C A, Langan, S M, Nassanga, B, Rodrigues, L C, Ring, S & Pearce, N 2018, ' Understanding asthma phenotypes : the World Asthma Phenotypes (WASP) international collaboration ', ERJ Open Research, vol. 4, no. 3 . https://doi.org/10.1183/23120541.00013-2018

The World Asthma Phenotypes (WASP) study started in 2016 and has been conducted in five centres, in the UK, New Zealand, Brazil, Ecuador and Uganda. The objectives of this study are to combine detailed biomarker and clinical information in order to 1

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