Genetic Associations with Obstructive Sleep Apnea Traits in Hispanic/Latino Americans

Autor: Be, Cade, Chen H, Am, Stilp, Kj, Gleason, Tamar Sofer, Ancoli-Israel S, Arens R, Gi, Bell, Je, Below, Ac, Bjonnes, Chun S, Mp, Conomos, Ds, Evans, Wc, Johnson, Ac, Frazier-Wood, Jm, Lane, Ek, Larkin, Js, Loredo, Ws, Post, Ar, Ramos

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4d0db3b050b72d39a70e76caa8a2b33a
http://europepmc.org/abstract/med/26977737

Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes.

Autor: Keener R; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Chhetri SB; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Connelly CJ; Department of Molecular Biology and Genetics, Johns Hopkins University, Baltimore, MD, USA., Taub MA; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Conomos MP; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Weinstock J; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Ni B; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA., Strober B; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA., Aslibekyan S; University of Alabama at Birmingham, Birmingham, AL, USA., Auer PL; Division of Biostatistics, Institute for Health & Equity, and Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Barwick L; LTRC Data Coordinating Center, The Emmes Company, LLC, Rockville, MD, USA., Becker LC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA., Blangero J; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Bleecker ER; Department of Medicine, Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.; Division of Pharmacogenomics, University of Arizona, Tucson, AZ, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Cade BE; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA., Celedon JC; Division of Pediatric Pulmonary Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Chang YC; Department of Internal Medicine, National Taiwan University, Taipei, Taiwan.; Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; The National Heart, Lung, and Blood Institute, Boston University's Framingham Heart Study, Framingham, MA, USA., Custer B; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA., Freedman BI; Internal Medicine - Nephrology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Gladwin MT; School of Medicine, University of Maryland, Baltimore, MD, USA., Heckbert SR; Department of Epidemiology, University of Washington, Seattle, WA, USA., Hou L; Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Evanston, IL, USA., Irvin MR; Department of Epidemiology, University of Alabama Birmingham, Birmingham, AL, USA., Isasi CR; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA., Johnsen JM; Department of Medicine and Institute for Stem Cell & Regenerative Medicine, University of Washington, Seattle, WA, USA., Kenny EE; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Center for Genomic Health, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Minster RL; Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, USA., Naseri T; Naseri & Associates Public Health Consultancy Firm and Family Health Clinic, Apia, Samoa.; International Health Institute, School of Public Health, Brown University, Providence, RI, USA., Viali S; Oceania University of Medicine, Apia, Samoa.; School of Medicine, National University of Samoa, Apia, Samoa.; Department of Chronic Disease Epidemiology, Yale University School of Public Health, New Haven, CT, USA., Nekhai S; Center for Sickle Cell Disease and Department of Medicine, College of Medicine, Howard University, Washington DC, USA., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Telen MJ; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Wu B; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA., Yanek LR; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yang IV; Departments of Biomedical Informatics, Medicine, and Epidemiology, University of Colorado, Boulder, CO, USA., Albert C; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular, Brigham and Women's Hospital, Boston, MA, USA., Arnett DK; Department of Epidemiology and Biostatistics, University of South Carolina, Columbia, SC, USA., Ashley-Koch AE; Department of Medicine, Duke University Medical Center, Durham, NC, USA., Barnes KC; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Blackwell TW; Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Burchard EG; Department of Medicine, University of California San Francisco, San Francisco, CA, USA.; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA., Carson AP; Department of Medicine, University of Mississippi Medical Center, Jackson, MI, USA., Chen Z; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Darbar D; Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA., de Andrade M; Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA., Ellinor PT; Cardiovascular Disease Initiative, The Broad Institute of MIT and Harvard, Cambridge, MA, USA., Fornage M; Institute of Molecular Medicine, McGovern Medical School, the University of Texas Health Science Center at Houston, Houston, TX, USA., Gelb BD; Mindich Child Health and Development Institute and Departments of Pediatrics and Genetics and Genomic Sciences, Icahn School of Medicine, New York, NY, USA., Gilliland FD; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA., He J; Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Islam T; Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA., Kaab S; Department of Cardiology, University Hospital, LMU Munich, Munich, Germany., Kardia SLR; Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA., Kelly S; Vitalant Research Institute, San Francisco, CA, USA.; University of California San Francisco Benioff Children's Hospital, Oakland, CA, USA., Konkle BA; Department of Medicine, University of Washington, Seattle, WA, USA., Kumar R; Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; The Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Martinez FD; Asthma & Airway Disease Research Center, University of Arizona, Tucson, AZ, USA., McGarvey ST; Department of Epidemiology & International Health Institute, Brown University School of Public Health, Providence, RI, USA., Meyers DA; Department of Medicine, Division of Genetics, Genomics and Precision Medicine, University of Arizona, Tucson, AZ, USA.; Division of Pharmacogenomics, University of Arizona, Tucson, AZ, USA., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Montgomery CG; Genes and Human Disease, Oklahoma Medical Research Foundation, Oklahoma City, OK, USA., North KE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Palmer ND; Department of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Peralta JM; Department of Human Genetics and South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Raby BA; Division of Pulmonary and Critical Care, Brigham and Women's Hospital, Boston, MA, USA.; Division of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA., Redline S; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA., Rich SS; Center for Public Health Genomics, Department of Public Health Sciences, University of Virginia, Charlottesville, VA, USA., Roden D; Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Ruczinski I; Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Schwartz D; Departments of Medicine and Immunology, University of Colorado, Boulder, CO, USA., Sciurba F; Division of Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Shoemaker MB; Departments of Medicine, Pharmacology, and Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA., Silverman EK; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Sinner MF; Department of Cardiology, University Hospital, LMU Munich, Munich, Germany., Smith NL; Department of Medicine, Tulane University School of Medicine, New Orleans, LA, USA., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA., Tiwari HK; Department of Biostatistics, University of Alabama Birmingham, Birmingham, AL, USA., Vasan RS; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Weiss ST; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Williams LK; Center for Individualized and Genomic Medicine Research (CIGMA), Department of Internal Medicine, Henry Ford Health System, Detroit, MI, USA., Zhang Y; Division of Pulmonary Allergy and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Ziv E; Department of Medicine, University of California San Francisco, San Francisco, CA, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Arvanitis M; Department of Medicine, Division of Cardiology, Johns Hopkins University, Baltimore, MD, USA., Greider CW; Department of Molecular Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA, USA.; University Professor Johns Hopkins University, Baltimore, MD, USA., Mathias RA; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. rmathias@jhmi.edu., Battle A; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Department of Genetic Medicine, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Malone Center for Engineering in Healthcare, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Data Science and AI Institute, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.

Publikováno v: Nature communications [Nat Commun] 2024 May 24; Vol. 15 (1), pp. 4417. Date of Electronic Publication: 2024 May 24.

Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.

Autor: de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Conomos MP; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Singh K; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Nicholson CJ; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Jain D; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Hasbani NR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Jiang W; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Lee S; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Lino Cardenas CL; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Lutz SM; PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Wong D; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Young EP; Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA., Tcheandjieu C; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Hilliard AT; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Palo Alto Veterans Institute for Research, Palo Alto, CA, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Bielak LF; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Musharoff S; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Clarke SL; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Terry JG; Department of Radiology, Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, TN, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Xu H; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Heard-Costa N; Boston University School of Medicine, Boston, MA, USA.; Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA., Wessel J; Department of Epidemiology, Fairbanks School of Public Health, Indiana University, Indianapolis, IN, USA.; Diabetes Translational Research Center, Indiana University, Indianapolis, IN, USA., Selvaraj MS; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Li RH; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Sun X; School of Public Health and Tropical Medicine, Department of Epidemiology, Tulane University, New Orleans, LA, USA.; College of Medicine, Department of Medicine, Division of Nephrology, University of Illinois Chicago, Chicago, IL, USA., Turner AW; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Stilp AM; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Khan A; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Newman AB; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Rasheed A; Center For Non-Communicable Diseases, Karachi, Pakistan., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Kral BG; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., McHugh CP; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Hodonsky C; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Saleheen D; Center For Non-Communicable Diseases, Karachi, Pakistan.; Department of Medicine, Columbia University Irving Medical Center, New York, NY, USA.; Department of Cardiology, Columbia University Irving Medical Center, New York, NY, USA., Herrington DM; Department of Internal Medicine, Section of Cardiovascular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Jacobs DR Jr; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN, USA., Nickerson DA; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Northwest Genomics Center, University of Washington, Seattle, WA, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Wang FF; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Heiss G; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Jun G; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Kinney GL; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Sigurslid HH; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Doddapaneni H; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Hall IM; Yale Center for Genomic Health, Yale School of Medicine, New Haven, CT, USA., Bensenor IM; Center for Clinical and Epidemiological Research, University Hospital, University of Sao Paulo Medical School, São Paulo, Brazil., Broome J; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Crapo JD; Department of Medicine, National Jewish Health, Denver, CO, USA., Wilson JG; Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA., Smith JA; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Blangero J; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Vargas JD; Medstar Heart and Vascular Institute, Medstar Georgetown University Hospital, Washington, DC, USA., Mosquera JV; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Smith JD; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Northwest Genomics Center, University of Washington, Seattle, WA, USA., Viaud-Martinez KA; Illumina Laboratory Services, Illumina Inc., San Diego, CA, USA., Ryan KA; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Young KA; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Lange LA; Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Emery LS; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Bittencourt MS; Center for Clinical and Epidemiological Research, University Hospital, University of Sao Paulo Medical School, São Paulo, Brazil., Budoff MJ; Department of Medicine, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Montasser ME; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Yu M; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Mahaney MC; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Mahamdeh MS; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Fornage M; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA., Franceschini N; Department of Epidemiology, Gillings School of Global Public health, University of North Carolina, Chapel Hill, NC, USA., Lotufo PA; Center for Clinical and Epidemiological Research, University Hospital, University of Sao Paulo Medical School, São Paulo, Brazil., Natarajan P; Cardiovascular Research Center and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Wong Q; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Mathias RA; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Division of Allergy and Clinical Immunology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA.; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA., Do R; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mehran R; Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tracy RP; Department of Pathology and Laboratory Medicine, Robert Larner, M.D. College of Medicine, University of Vermont, Burlington, VT, USA., Kim RW; Psomagen Inc., Rockville, MD, USA., Nelson SC; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Damrauer SM; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kardia SLR; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Fuster V; Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, Spain.; Mount Sinai Heart Center, New York, NY, USA., Napolioni V; Genomic And Molecular Epidemiology (GAME) Lab, School of Biosciences and Veterinary Medicine, University of Camerino, Camerino, Italy., Zhao W; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Tian W; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA., Yin X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Min YI; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Manning AK; Clinical and Translation Epidemiology Unit, Department of Medicine, Massachusetts General Hospital, Boston, MA, USA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Peloso G; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Kelly TN; College of Medicine, Department of Medicine, Division of Nephrology, University of Illinois Chicago, Chicago, IL, USA., O'Donnell CJ; VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Curran JE; Department of Human Genetics, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA.; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley School of Medicine, Brownsville, TX, USA., Zapol WM; Department of Anesthesia, Critical Care and Pain Medicine at Massachusetts General Hospital, Boston, MA, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Becker LC; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Correa A; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA.; Department of Population Health Science, University of Mississippi Medical Center, Jackson, MS, USA., Mitchell BD; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Carr JJ; Department of Radiology, Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University Medical Center, Nashville, TN, USA., Pereira AC; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Laboratory of Genetics and Molecular Cardiology, Heart Institute, University of São Paulo, São Paulo, Brazil., Assimes TL; VA Palo Alto Healthcare System, Palo Alto, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Stitziel NO; Cardiovascular Division, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA., Hokanson JE; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Laurie CA; Genetic Analysis Center, Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Vasan RS; Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA, USA.; Department of Medicine, Boston University School of Medicine, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA., Post WS; Division of Cardiology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Peyser PA; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Miller CL; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA., Malhotra R; Cardiovascular Research Center, Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Publikováno v: Nature cardiovascular research [Nat Cardiovasc Res] 2023 Dec; Vol. 2 (12), pp. 1159-1172. Date of Electronic Publication: 2023 Dec 04.

WHOLE GENOME SEQUENCING ANALYSIS OF BODY MASS INDEX IDENTIFIES NOVEL AFRICAN ANCESTRY-SPECIFIC RISK ALLELE.

Autor: Zhang X; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Highland HM; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Chami N; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Xu H; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Wang Z; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ferrier K; Division of Biomedical Informatics and Personalized Medicine, School of Medicine University of Colorado, Anschutz Medical Campus, Aurora, CO, USA., Chittoor G; Population Health Sciences, Geisinger, Danville, PA, USA., Josyula NS; Population Health Sciences, Geisinger, Danville, PA, USA., Li X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA., Li Z; Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, USA., Allison MA; Department of Family Medicine, Division of Preventive Medicine, The University of California San Diego, La Jolla, CA, USA., Becker DM; Department of Medicine, General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Boorgula MP; Department of Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Broome JG; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA.; Department of Medicine, Division of Medical Genetics, University of Washington, Seattle, WA, USA., Buth EJ; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Carlson CS; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Chang KM; The Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.; University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Chavan S; Department of Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Chiu YF; Institute of Population Health Sciences, National Health Research Institutes, Taipei, Taiwan., Chuang LM; Department of Internal Medicine, Division of Metabolism/Endocrinology, National Taiwan University Hospital, Taipei, Taiwan., Conomos MP; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., DeMeo DL; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Du M; Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Duggirala R; Life Sciences, College of Arts and Sciences, Texas A&M University-San Antonio, San Antonio, TX, USA., Eng C; Department of Medicine, Lung Biology Center, University of California, San Francisco, San Francisco, CA, USA., Fohner AE; Epidemiology, Institute of Public Health Genetics, School of Public Health, University of Washington, Seattle, WA, USA., Freedman BI; Internal Medicine, Section on Nephrology, Wake Forest School of Medicine, Winston-Salem, NC, USA., Garrett ME; Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA., Guo X; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Haiman C; Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Heavner BD; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Hidalgo B; Department of Epidemiology, School of Public Health, University of Alabama at Birmingham School of Public Health, Birmingham, AL, USA., Hixson JE; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Ho YL; Veterans Affairs Boston Healthcare System, Boston, MA, USA., Hobbs BD; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Hu D; Department of Medicine, Lung Biology Center, University of California, San Francisco, San Francisco, CA, USA., Hui Q; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Atlanta VA Health Care System, Decatur, GA, USA., Hwu CM; Department of Medicine, Division of Endocrinology and Metabolism, Taipei Veterans General Hospital, Taipei, Taiwan, Taiwan., Jackson RD; Endocrinology, Ohio State University, Columbus, OH, USA., Jain D; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Kalyani RR; Department of Medicine, Endocrinology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kelly TN; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Lange EM; Division of Biomedical Informatics and Personalized Medicine, School of Medicine University of Colorado, Anschutz Medical Campus, Aurora, CO, USA., LeNoir M; Department of Pediatrics, Bay Area Pediatrics, Oakland, CA, USA., Li C; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Marchand LL; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., McDonald MN; Department of Medicine, Pulmonary, Allergy and Critical Care, University of Alabama at Birmingham, Birmingham, AL, USA., McHugh CP; Department of Biostatistics, School of Public Health, University of Washington, Seattle, WA, USA., Morrison AC; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Naseri T; Ministry of Health, Government of Samoa, Apia, Samoa., O'Connell J; Department of Medicine, Program for Personalized and Genomic Medicine, University of Maryland, Baltimore, MD, USA., O'Donnell CJ; Veterans Affairs Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pankow JS; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Perry JA; Department of Medicine, School of Medicine, University of Maryland, Baltimore, MD, USA., Peters U; Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, WA, USA., Preuss MH; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Rao DC; Division of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., Regan EA; Department of Medicine, Rheumatology, National Jewish Health, Denver, CO, USA., Reupena SM; Lutia I Puava Ae Mapu I Fagalele, Apia, Samoa., Roden DM; Medicine, Pharmacology, and Biomedical Informatics, Clinical Pharmacology and Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Rodriguez-Santana J; Centro de Neumologia Pediatrica, San Juan, PR, USA., Sitlani CM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Tiwari HK; Department of Biostatistics, University of Alabama at Birmingham School of Public Health, Birmingham, AL, USA., Vasan RS; Department of Medicine, School of Medicine, Boston University, Boston, MA, USA., Wang Z; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA., Weeks DE; Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Wessel J; Department of Epidemiology, Indiana University, Indianapolis, IN, USA.; Department of Medicine, Indiana University, Indianapolis, IN, USA.; Diabaetes Translational Research Center, Indiana University, Indianapolis, IN, USA., Wiggins KL; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Wilkens LR; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA., Wilson PWF; Atlanta VA Health Care System, Decatur, GA, USA.; Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA., Yanek LR; Department of Medicine, General Internal Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Yoneda ZT; Department of Medicine, Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Zöllner S; Department of Biostatistics, Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA., Arnett DK; Department of Epidemiology, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA., Ashley-Koch AE; Department of Medicine, Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, USA., Barnes KC; Department of Medicine, School of Medicine, University of Colorado, Aurora, CO, USA., Blangero J; Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, University of Texas Rio Grande Valley, Brownsville, TX, USA., Boerwinkle E; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Burchard EG; Bioengineering and Therapeutic Sciences and Medicine, Lung Biology Center, University of California, San Francisco, San Francisco, CA, USA., Carson AP; Department of Medicine, University of Mississippi, Jackson, MI, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; Department of Medical Genetics, Genomic Outcomes, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Curran JE; Department of Human Genetics and South Texas Diabetes and Obesity Institute, School of Medicine, University of Texas Rio Grande Valley, Brownsville, TX, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA.; Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Gordeuk VR; Department of Medicine, School of Medicine, University of Illinois at Chicago, Chicago, IL, USA., He J; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, USA., Heckbert SR; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Hou L; Northwestern University, Chicago, IL, USA., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, AL, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Minster RL; Department of Human Genetics, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA., Mitchell BD; Department of Medicine, Division of Endocrinology, Diabetes and Nutrition, University of Maryland, Baltimore, MD, USA., Nouraie M; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA., Rich SS; Public Health Science, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Rotter JI; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Shoemaker MB; Department of Medicine, Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Smith NL; Department of Epidemiology, School of Public Health, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Kaiser Permanente Washington, Seattle, WA, USA.; Seattle Epidemiologic Research and Information Center, Office of Research and Development, Department of Veterans Affairs, Seattle, WA, USA., Taylor KD; Department of Pediatrics, Genomic Outcomes, The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Telen MJ; Department of Medicine, Hematology, Duke University Medical Center, Durham, NC, USA., Weiss ST; Department of Medicine, Channing Division of Network Medicine, Harvard Medical School, Boston, MA, USA., Zhang Y; Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Heard-Costa N; Framingham Heart Study, School of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Sun YV; Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA, USA.; Atlanta VA Health Care System, Decatur, GA, USA., Lin X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.; Department of Statistics, Harvard University, Boston, MA, USA., Adrienne Cupples L; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Lange LA; Division of Biomedical Informatics and Personalized Medicine, School of Medicine University of Colorado, Anschutz Medical Campus, Aurora, CO, USA., Liu CT; Department of Biostatistics, School of Public Health, Boston University, Boston, MA, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Justice AE; Population Health Sciences, Geisinger, Danville, PA, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Aug 22. Date of Electronic Publication: 2023 Aug 22.

Whole Genome Analysis of Venous Thromboembolism: the Trans-Omics for Precision Medicine Program.

Autor: Seyerle AA; Division of Pharmaceutical Outcomes & Policy, Eshelman School of Pharmacy (A.A.S.), University of North Carolina at Chapel Hill.; Carolina Health Informatics Program (A.A.S.), University of North Carolina at Chapel Hill., Laurie CA; Department of Biostatistics (C.A.L., D.J., M.P.C., S.M.G., B.M., C.C.L., K.R.), University of Washington, Seattle., Coombes BJ; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN (B.J.C., M.d.A.)., Jain D; Department of Biostatistics (C.A.L., D.J., M.P.C., S.M.G., B.M., C.C.L., K.R.), University of Washington, Seattle., Conomos MP; Department of Biostatistics (C.A.L., D.J., M.P.C., S.M.G., B.M., C.C.L., K.R.), University of Washington, Seattle., Brody J; Cardiovascular Health Research Unit (J.B., S.R.H., K.L.W., B.M.P., N.L.S.), University of Washington, Seattle., Chen MH; NHLB's The Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA (M.-H.C., A.D.J.)., Gogarten SM; Department of Biostatistics (C.A.L., D.J., M.P.C., S.M.G., B.M., C.C.L., K.R.), University of Washington, Seattle., Beutel KM; NHLB's The Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA (M.-H.C., A.D.J.).; Department of Laboratory Medicine & Pathology, School of Medicine (K.M.B., N.P.), University of Minnesota, Minneapolis., Gupta N; Broad Institute of MIT & Harvard, Cambridge, MA (N.G., S.B.G.)., Heckbert SR; Cardiovascular Health Research Unit (J.B., S.R.H., K.L.W., B.M.P., N.L.S.), University of Washington, Seattle.; Department of Epidemiology (S.R.H., A.P.R., B.M.P., N.L.S.), University of Washington, Seattle., Jackson RD; Division of Endocrinology, Diabetes & Metabolism, Ohio State University, Columbus (R.D.J.)., Johnson AD; NHLB's The Framingham Heart Study, Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham, MA (M.-H.C., A.D.J.)., Ko D; Cardiovascular Medicine Section, Boston University School of Medicine (D.K.)., Manson JE; Department of Epidemiology, TH Chan School of Public Health, Harvard University, Boston, MA (J.E.M.)., McKnight B; Department of Biostatistics (C.A.L., D.J., M.P.C., S.M.G., B.M., C.C.L., K.R.), University of Washington, Seattle., Metcalf GA; Human Genome Sequencing Center, Baylor College of Medicine (G.A.M., R.A.G.)., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston (A.C.M., E.B.)., Reiner AP; Department of Epidemiology (S.R.H., A.P.R., B.M.P., N.L.S.), University of Washington, Seattle., Sofer T; Division of Sleep & Circadian Disorders, Brigham and Women's Hospital (T.S.).; Department of Medicine, Harvard Medical School, Boston, MA (T.S.)., Tang W; Division of Epidemiology & Community Health (W.T., J.S.P.), University of Minnesota, Minneapolis., Wiggins KL; Cardiovascular Health Research Unit (J.B., S.R.H., K.L.W., B.M.P., N.L.S.), University of Washington, Seattle., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston (A.C.M., E.B.)., de Andrade M; Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN (B.J.C., M.d.A.)., Gabriel SB; Broad Institute of MIT & Harvard, Cambridge, MA (N.G., S.B.G.)., Gibbs RA; Human Genome Sequencing Center, Baylor College of Medicine (G.A.M., R.A.G.)., Laurie CC; Department of Biostatistics (C.A.L., D.J., M.P.C., S.M.G., B.M., C.C.L., K.R.), University of Washington, Seattle., Psaty BM; Cardiovascular Health Research Unit (J.B., S.R.H., K.L.W., B.M.P., N.L.S.), University of Washington, Seattle.; Department of Epidemiology (S.R.H., A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.; Departments of Medicine & Health Services (B.M.P.), University of Washington, Seattle.; Kaiser Permanente Washington Health Rsrch Inst, Seattle, WA (B.M.P.)., Vasan RS; Departments of Medicine& Epidemiology, Boston University, MA (R.S.V.)., Rice K; Department of Biostatistics (C.A.L., D.J., M.P.C., S.M.G., B.M., C.C.L., K.R.), University of Washington, Seattle., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center (C.K.)., Pankow JS; Division of Epidemiology & Community Health (W.T., J.S.P.), University of Minnesota, Minneapolis., Smith NL; Cardiovascular Health Research Unit (J.B., S.R.H., K.L.W., B.M.P., N.L.S.), University of Washington, Seattle.; Department of Epidemiology (S.R.H., A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.; Seattle Epidemiologic Research & Information Center, VA Office of Research & Development, Seattle, WA (N.L.S.)., Pankratz N; Department of Laboratory Medicine & Pathology, School of Medicine (K.M.B., N.P.), University of Minnesota, Minneapolis.

Publikováno v: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2023 Apr; Vol. 16 (2), pp. e003532. Date of Electronic Publication: 2023 Mar 24.