The evolving role of investigative toxicology in the pharmaceutical industry.

Autor: Pognan F; Discovery and Investigative Safety, Novartis Pharma AG, Basel, Switzerland. francois.pognan@novartis.com., Beilmann M; Nonclinical Drug Safety Germany, Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany., Boonen HCM; Drug Safety, Dept of Exploratory Toxicology, Lundbeck A/S, Valby, Denmark., Czich A; R&D Preclinical Safety, Sanofi, Frankfurt, Germany., Dear G; In Vitro In Vivo Translation, GlaxoSmithKline David Jack Centre for Research, Ware, UK., Hewitt P; Chemical and Preclinical Safety, Merck Healthcare KGaA, Darmstadt, Germany., Mow T; Safety Pharmacology and Early Toxicology, Novo Nordisk A/S, Maaloev, Denmark., Oinonen T; Preclinical Safety, Orion Corporation, Espoo, Finland., Roth A; Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland., Steger-Hartmann T; Investigational Toxicology, Bayer AG, Berlin, Germany., Valentin JP; Non-Clinical Safety Evaluation, UCB Biopharma SRL, Braine-l'Alleud, Belgium., Van Goethem F; Predictive, Investigative & Translational Toxicology, Nonclinical Safety, Janssen Research & Development, Beerse, Belgium., Weaver RJ; Innovation Life Cycle Management, Institut de Recherches Internationales Servier, Suresnes, France., Newham P; Clinical Pharmacology and Safety Sciences, AstraZeneca R&D, Cambridge, UK. peter.newham@astrazeneca.com.

Publikováno v: Nature reviews. Drug discovery [Nat Rev Drug Discov] 2023 Apr; Vol. 22 (4), pp. 317-335. Date of Electronic Publication: 2023 Feb 13.

Arthroscopic repair of inferior glenoid labrum tears (Down Under lesions) produces similar outcomes to other glenoid tears.

Autor: Page RS; Barwon Centre for Orthopaedic Research and Education (B-CORE), St John of God Hospital Geelong and Barwon Health, Myers Street, Geelong, VIC, 3227, Australia. Richard.page@deakin.edu.au.; School of Medicine, Deakin University, Geelong Campus at Waurn Ponds, Geelong, VIC, Australia. Richard.page@deakin.edu.au., Fraser-Moodie JA; Wishaw General Hospital, Wishaw, UK., Bayne G; Northern Lincolnshire and Goole Hospitals NHS Foundation Trust, Grimsby, Lincolnshire, UK., Mow T; St George Hospital, Sydney, NSW, Australia., Lane S; interadata, Geelong, VIC, Australia., Brown G; Geelong Orthopaedics and Barwon Health, Geelong, VIC, Australia., Gill SD; Barwon Centre for Orthopaedic Research and Education (B-CORE), St John of God Hospital Geelong and Barwon Health, Myers Street, Geelong, VIC, 3227, Australia.; School of Medicine, Deakin University, Geelong Campus at Waurn Ponds, Geelong, VIC, Australia.

Publikováno v: Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA [Knee Surg Sports Traumatol Arthrosc] 2021 Dec; Vol. 29 (12), pp. 4015-4021. Date of Electronic Publication: 2021 Aug 29.

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Inhibition of Neural Crest Cell Migration by Strobilurin Fungicides and Other Mitochondrial Toxicants.

Autor: Magel, Viktoria¹ (AUTHOR), Blum, Jonathan¹ (AUTHOR), Dolde, Xenia¹ (AUTHOR), Leisner, Heidrun¹ (AUTHOR), Grillberger, Karin² (AUTHOR), Khalidi, Hiba³ (AUTHOR), Gardner, Iain³ (AUTHOR), Ecker, Gerhard F.² (AUTHOR), Pallocca, Giorgia^1,4 (AUTHOR), Dreser, Nadine^1,4 (AUTHOR), Leist, Marcel^1,4 (AUTHOR) marcel.leist@uni-konstanz.de

Publikováno v: Cells (2073-4409). Dec2024, Vol. 13 Issue 24, p2057. 24p.

Re‐evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives.

Autor: Castle, Laurence (AUTHOR), Andreassen, Monica (AUTHOR), Aquilina, Gabriele (AUTHOR), Bastos, Maria Lourdes (AUTHOR), Boon, Polly (AUTHOR), Fallico, Biagio (AUTHOR), FitzGerald, Reginald (AUTHOR), Frutos Fernandez, Maria Jose (AUTHOR), Grasl‐Kraupp, Bettina (AUTHOR), Gundert‐Remy, Ursula (AUTHOR), Gürtler, Rainer (AUTHOR), Houdeau, Eric (AUTHOR), Kurek, Marcin (AUTHOR), Louro, Henriqueta (AUTHOR), Morales, Patricia (AUTHOR), Passamonti, Sabina (AUTHOR), Batke, Monika (AUTHOR), Bruzell, Ellen (AUTHOR), Chipman, James (AUTHOR), Cheyns, Karlien (AUTHOR)

Publikováno v: EFSA Journal. Nov2024, Vol. 22 Issue 11, p1-106. 106p.