Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Moustafa Elkalaf"'
Autor:
Tumisang Edward Maseko, Eva Peterová, Moustafa Elkalaf, Darja Koutová, Jan Melek, Pavla Staňková, Veronika Špalková, Reem Matar, Halka Lotková, Zuzana Červinková, Otto Kučera
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1179 (2024)
Various strategies have been employed to improve the reliability of 2D, 3D, and co-culture in vitro models of nonalcoholic fatty liver disease, including using extracellular matrix proteins such as collagen I to promote cell adhesion. While studies h
Externí odkaz:
https://doaj.org/article/f49d5b3112a34a999a8e994a2eb89568
Autor:
Tereza Žalmanová, Kristýna Hošková, Šárka Prokešová, Jan Nevoral, Michal Ješeta, Michal Benc, Young-Joo Yi, Jiří Moravec, Beáta Močáryová, Stanislava Martínková, Josef Fontana, Moustafa Elkalaf, Jan Trnka, Jana Žáková, Jaroslav Petr
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Bisphenol S (BPS), the main replacement for bisphenol A (BPA), is thought to be toxic, but limited information is available on the effects of Bisphenol S on ovarian follicles. In our study, we demonstrated the presence of Bisphenol S in the follicula
Externí odkaz:
https://doaj.org/article/9114cae5029f4961bc7db7d15ce87c44
Autor:
Ivana Fiserova, Minh Duc Trinh, Moustafa Elkalaf, Lukas Vacek, Marek Heide, Stanislava Martinkova, Kamila Bechynska, Vit Kosek, Jana Hajslova, Ondrej Fiser, Petr Tousek, Jan Polak
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Recent studies have suggested a pathogenetic link between impaired mitochondria and Takotsubo syndrome (TTS), which is closely connected with catecholamine overstimulation, poor outcomes, and changes in lipid metabolism. We investigated the changes i
Externí odkaz:
https://doaj.org/article/8b75d22593ec495eb194cf98336081f6
Autor:
Zuzana Lattova, Lucie Slovakova, Andrea Plihalova, Jan Gojda, Moustafa Elkalaf, Katerina Westlake, Jan Polak
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5308 (2023)
The molecular mechanisms linking obstructive sleep apnea (OSA) with type 2 diabetes mellitus (T2DM) remain unclear. This study investigated the effect of OSA on skeletal muscle lipid oxidation in nondiabetic controls and in type 2 diabetes (T2DM) pat
Externí odkaz:
https://doaj.org/article/47f30ba871114828a65ceb99a09c4926
Autor:
Lukas Vacek, Ales Dvorak, Kamila Bechynska, Vit Kosek, Moustafa Elkalaf, Minh Duc Trinh, Ivana Fiserova, Katerina Pospisilova, Lucie Slovakova, Libor Vitek, Jana Hajslova, Jan Polak
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Obstructive sleep apnea syndrome, characterized by repetitive episodes of tissue hypoxia, is associated with several metabolic impairments. Role of fatty acids and lipids attracts attention in its pathogenesis for their metabolic effects. Parallelly,
Externí odkaz:
https://doaj.org/article/0f3252c7e9e442509bbef5ffbe6ca6e2
Autor:
Blanka Šestáková, Ladislava Schröterová, Aleš Bezrouk, Dana Čížková, Moustafa Elkalaf, Radim Havelek, Emil Rudolf, Věra Králová
Publikováno v:
Nanomaterials, Vol 12, Iss 12, p 2074 (2022)
Graphene and its derivatives are popular nanomaterials used worldwide in many technical fields and biomedical applications. Due to such massive use, their anticipated accumulation in the environment is inevitable, with a largely unknown chronic influ
Externí odkaz:
https://doaj.org/article/52b454a58e2a4246b6e0ecc00e01d5fd
Autor:
Pavla Staňková, Otto Kučera, Eva Peterová, Moustafa Elkalaf, David Rychtrmoc, Jan Melek, Miroslav Podhola, Veronika Zubáňová, Zuzana Červinková
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 6908 (2021)
Mitochondria play an essential role in the pathogenesis of nonalcoholic fatty liver disease (NAFLD). Previously, we found that succinate-activated respiration was the most affected mitochondrial parameter in mice with mild NAFLD. In this study, we fo
Externí odkaz:
https://doaj.org/article/e990db6079d94ce5b5ee0528f3621b3f
Autor:
Martina Musutova, Moustafa Elkalaf, Natalie Klubickova, Michal Koc, Stanislav Povysil, Jan Rambousek, Beatriz Volckaert, Frantisek Duska, Minh Duc Trinh, Martin Kalous, Jan Trnka, Kamila Balusikova, Jan Kovar, Jan Polak
Publikováno v:
Frontiers in Endocrinology, Vol 9 (2018)
Metabolic impairments associated with obstructive sleep apnea syndrome (OSA) are linked to tissue hypoxia, however, the explanatory molecular and endocrine mechanisms remain unknown. Using gas-permeable cultureware, we studied the chronic effects of
Externí odkaz:
https://doaj.org/article/a805d61445054cef83f2a172caf065c2
Autor:
Martin Weiszenstein, Nela Pavlikova, Moustafa Elkalaf, Petr Halada, Ondrej Seda, Jan Trnka, Jan Kovar, Jan Polak
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152382 (2016)
Pericellular oxygen concentration represents an important factor in the regulation of cell functions, including cell differentiation, growth and mitochondrial energy metabolism. Hypoxia in adipose tissue has been associated with altered adipokine sec
Externí odkaz:
https://doaj.org/article/0f19a7a276ce426f84eb141d8958f6ec
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0161413 (2016)
Methyltriphenylphosphonium (TPMP) salts have been widely used to measure the mitochondrial membrane potential and the triphenylphosphonium (TPP+) moiety has been attached to many bioactive compounds including antioxidants to target them into mitochon
Externí odkaz:
https://doaj.org/article/f77fa5fcb7a34be5a53db9603c252eea