Zobrazeno 1 - 10
of 623
pro vyhledávání: '"Moustafa E"'
Autor:
Fatmah Ali S. Alasmary, Dalal A. Abdullah, Vijay H. Masand, Abir Ben Bacha, Abdelsattar Mansour Omar Ebeid, Moustafa E. El-Araby, Ahmed M Alafeefy
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Quinoxalines are benzopyrazine derivatives with significant therapeutic impact in the pharmaceutical industry. They proved to be useful against inflammation, bacterial, fungal, viral infection, diabetes and other applications. Very recently, in Janua
Externí odkaz:
https://doaj.org/article/ffec69356bab4219b307daf6812c7f51
Autor:
Mohd Rehan, Firoz Ahmed, Mohammad Imran Khan, Hifzur Rahman Ansari, Shazi Shakil, Moustafa E. El-Araby, Salman Hosawi, Mohammad Saleem
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
The epidermal growth factor receptor (EGFR) plays a crucial role in regulating cellular growth and survival, and its dysregulation is implicated in various cancers, making it a prime target for cancer therapy. Natural compounds known as catechins hav
Externí odkaz:
https://doaj.org/article/33075e6c8b4c43d68a639afe339dd7c7
Publikováno v:
Al-Azhar Assiut Medical Journal, Vol 21, Iss 1, Pp 21-28 (2023)
Background and aim Fluoride causes liver function impairment, decrease in metabolic activities, and inhibits certain antioxidant enzymes and molecules. This study aims to clarify the possible histological alterations caused by sodium fluoride (NaF) o
Externí odkaz:
https://doaj.org/article/d0063ce714b14b36b9a53d479748aae9
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract The aim of this study is to describe the performance of the aluminum oxide nanoparticle and metal aluminate spinel nanoparticle as photo-anodes in quantum dot photovoltaic. By using a sol–gel auto combustion method, Al2O3 NPs, CoAl2O4, CuA
Externí odkaz:
https://doaj.org/article/bb02169a1f914cd8a4ac7ee81e37b1f9
Autor:
Moustafa E. Motawee, Ahmed A. Damanhory, Hany Sakr, Mohamed Mansour Khalifa, Tarek Atia, Mohamed M. Elfiky, Muhammad Maher, Hader I. Sakr
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: Cadmium (Cd) is a toxic heavy metal used in many industries. Since the second half of the 20th century, legislation on Cd use was put to limit the exponential rise in its environmental levels. This study aimed to investigate Cd’s functi
Externí odkaz:
https://doaj.org/article/c920925dbdb54b18a01e8720b010fd94
Autor:
Abdelsattar M. Omar, Maan T. Khayat, Farid Ahmed, Yosra A. Muhammad, Azizah M. Malebari, Sara M. Ibrahim, Mohammad I. Khan, Dhaval K. Shah, Wayne E. Childers, Moustafa E. El-Araby
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tirbanibulin (KX2-391, KX-01), a dual non-ATP (substrate site) Src kinase and tubulin-polymerization inhibitor, demonstrated a universal anti-cancer activity for variety of cancer types. The notion that KX2-391 is a highly selective Src kinase inhibi
Externí odkaz:
https://doaj.org/article/74f0539c28fe4afaab248255f807b3c2
Autor:
Hader Ibrahim Sakr, Mohamed A. Amen, Laila A. Rashed, Akef A. Khowailed, Hazem A. Sayed, Moustafa E. Motawee, Hany Sakr, Mohamed Mansour Khalifa
Publikováno v:
Archives of Medical Science, Vol 20, Iss 2, Pp 618-631 (2020)
Introduction Type 2 diabetes mellitus (DM) and Alzheimer’s disease (AD) are two major medical conditions that constitute a significant financial burden on most healthcare systems. Due to AD sharing “insulin resistance” mechanistic features with
Externí odkaz:
https://doaj.org/article/ee445188e25a451481d7df8f689bc2e7
Autor:
Moustafa E. El-Araby, Abdelsattar M. Omar, Sameh H. Soror, Stefan T. Arold, Maan T. Khayat, Hani Z. Asfour, Faida Bamane, Mahmoud A. Elfaky
Publikováno v:
Journal of Advanced Research, Vol 24, Iss , Pp 251-259 (2020)
NS4A is a non-structural multi-tasking small peptide that is essential for HCV maturation and replication. The central odd-numbered hydrophobic residues of NS4A (Val-23‘ to Leu-31‘)ii The prime symbol (`) is used to distinguish between NS4A resid
Externí odkaz:
https://doaj.org/article/ac89ecf67fe74d4ca4ed1b10c55463c0
Autor:
Maan T. Khayat, Abdelsattar M. Omar, Farid Ahmed, Mohammad I. Khan, Sara M. Ibrahim, Yosra A. Muhammad, Azizah M. Malebari, Thikryat Neamatallah, Moustafa E. El-Araby
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Structural changes of small-molecule drugs may bring interesting biological properties, especially in the field of kinase inhibitors. We sought to study tirbanibulin, a first-in-class dual Src kinase (non-ATP competitive)/tubulin inhibitor because th
Externí odkaz:
https://doaj.org/article/539bc391ade147b39a5632057cf3fa93
Autor:
Maan T. Khayat, Abdelsattar M. Omar, Mahmoud A. Elfaky, Yosra A. Muhammad, Elaf A. Felemban, Khalid M. El-Say, Moustafa E. El-Araby
Publikováno v:
Heteroatom Chemistry, Vol 2022 (2022)
Chronic Hepatitis C is a global health threat and a silent killer. Regardless of the profound progress in preventing and treating this disease, research continues to discover new direct antiviral agents (DAAs), especially against novel targets. Our r
Externí odkaz:
https://doaj.org/article/320200ef08d44feba563a7dac4ce48f5