Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Mousseau JJ"'
3-Sulfanyl-oxetanes are presented as promising novel bioisosteric replacements for thioesters or benzyl sulfides. From oxetan-3-ols, a mild and inexpensive Li catalyst enables chemoselective C–OH activation and thiol alkylation. Oxetane sulfides ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::13e3fddab41f2e13709baa9ed474272f
http://hdl.handle.net/10044/1/54378
http://hdl.handle.net/10044/1/54378
The first examples of 3,3-diaryloxetanes are prepared in a lithium-catalyzed and substrate dependent divergent Friedel–Crafts reaction. para-Selective Friedel–Crafts reactions of phenols using oxetan-3-ols afford 3,3-diaryloxetanes by displacemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::2ad07361cf2a481eb079e05837593547
http://hdl.handle.net/10044/1/39877
http://hdl.handle.net/10044/1/39877
Autor:
Dubois MAJ; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Rojas JJ; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Sterling AJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, U.K., Broderick HC; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Smith MA; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., White AJP; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Miller PW; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Choi C; Pfizer Global Research and Development, 445 Eastern Point Rd., Groton, Connecticut 06340, United States., Mousseau JJ; Pfizer Global Research and Development, 445 Eastern Point Rd., Groton, Connecticut 06340, United States., Duarte F; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford OX1 3TA, U.K., Bull JA; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K.
Publikováno v:
The Journal of organic chemistry [J Org Chem] 2023 May 19; Vol. 88 (10), pp. 6476-6488. Date of Electronic Publication: 2023 Mar 03.
Autor:
Allais C; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Bernhardson D; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Brown AR; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Chinigo GM; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Desrosiers JN; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., DiRico KJ; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Hotham I; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Jones BP; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Kulkarni SA; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Lewis CA; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Lira R; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Loach RP; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Morse PD; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Mousseau JJ; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Perry MA; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Peng Z; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Place DW; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Rane AM; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Samp L; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Singer RA; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Wang Z; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Weisenburger GA; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States., Yayla HG; Medicine Design, Pfizer Inc., Groton, Connecticut06340, United States., Zanghi JM; Chemical Research and Development, Pfizer Inc., Groton, Connecticut06340, United States.
Publikováno v:
Organic process research & development [Org Process Res Dev] 2023 Feb 03. Date of Electronic Publication: 2023 Feb 03.
Autor:
Raina K; co-corresponding authors.; Halda Therapeutics OpCo Inc, New Haven CT USA., Forbes CD; Halda Therapeutics OpCo Inc, New Haven CT USA., Stronk R; Halda Therapeutics OpCo Inc, New Haven CT USA., Rappi JP Jr; Halda Therapeutics OpCo Inc, New Haven CT USA., Eastman KJ; Halda Therapeutics OpCo Inc, New Haven CT USA., Gerritz SW; Halda Therapeutics OpCo Inc, New Haven CT USA., Yu X; Halda Therapeutics OpCo Inc, New Haven CT USA., Li H; Halda Therapeutics OpCo Inc, New Haven CT USA., Bhardwaj A; Halda Therapeutics OpCo Inc, New Haven CT USA., Forgione M; Halda Therapeutics OpCo Inc, New Haven CT USA., Hundt A; Halda Therapeutics OpCo Inc, New Haven CT USA., King MP; Halda Therapeutics OpCo Inc, New Haven CT USA., Posner ZM; Halda Therapeutics OpCo Inc, New Haven CT USA., Denny A; Halda Therapeutics OpCo Inc, New Haven CT USA., McGovern A; Halda Therapeutics OpCo Inc, New Haven CT USA., Puleo DE; Halda Therapeutics OpCo Inc, New Haven CT USA., Garvin E; Halda Therapeutics OpCo Inc, New Haven CT USA., Chenard R; Halda Therapeutics OpCo Inc, New Haven CT USA., Zaware N; Halda Therapeutics OpCo Inc, New Haven CT USA., Mousseau JJ; Halda Therapeutics OpCo Inc, New Haven CT USA., Macaluso J; Halda Therapeutics OpCo Inc, New Haven CT USA., Martin M; Halda Therapeutics OpCo Inc, New Haven CT USA., Bassoli K; Halda Therapeutics OpCo Inc, New Haven CT USA., Jones K; Halda Therapeutics OpCo Inc, New Haven CT USA., Garcia M; Halda Therapeutics OpCo Inc, New Haven CT USA., Howard K; Halda Therapeutics OpCo Inc, New Haven CT USA., Smith LM; Halda Therapeutics OpCo Inc, New Haven CT USA., Chen JM; Halda Therapeutics OpCo Inc, New Haven CT USA., De Leon CA; Department of Molecular, Cellular, & Developmental Biology, Yale University New Haven CT USA., Hines J; Department of Molecular, Cellular, & Developmental Biology, Yale University New Haven CT USA., Kayser-Bricker KJ; Halda Therapeutics OpCo Inc, New Haven CT USA., Crews CM; co-corresponding authors.; Department of Molecular, Cellular, & Developmental Biology, Yale University New Haven CT USA.; Department of Pharmacology, Yale University New Haven CT USA.; Department of Chemistry, Yale University New Haven CT USA.
Publikováno v:
BioRxiv : the preprint server for biology [bioRxiv] 2023 Jan 02. Date of Electronic Publication: 2023 Jan 02.
Autor:
Rojas JJ; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Torrisi E; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K.; Department of Biomolecular Sciences, School of Pharmacy, University of Urbino 'Carlo Bo', P.za Rinascimento, 6, 61029 Urbino (PU), Italy., Dubois MAJ; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Hossain R; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., White AJP; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K., Zappia G; Department of Biomolecular Sciences, School of Pharmacy, University of Urbino 'Carlo Bo', P.za Rinascimento, 6, 61029 Urbino (PU), Italy., Mousseau JJ; Pfizer Worldwide Research, Development and Medical, Eastern Point Road, Groton, Connecticut 06340, United States., Choi C; Pfizer Worldwide Research, Development and Medical, Eastern Point Road, Groton, Connecticut 06340, United States., Bull JA; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, White City Campus, Wood Lane, London W12 0BZ, U.K.
Publikováno v:
Organic letters [Org Lett] 2022 Apr 01; Vol. 24 (12), pp. 2365-2370. Date of Electronic Publication: 2022 Mar 21.
Autor:
Rojas JJ; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK., Croft RA; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK., Sterling AJ; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK., Briggs EL; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK., Antermite D; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK., Schmitt DC; Pfizer Worldwide Research, Development and Medical, Groton, CT, USA., Blagojevic L; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK., Haycock P; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK., White AJP; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK., Duarte F; Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK., Choi C; Pfizer Worldwide Research, Development and Medical, Groton, CT, USA., Mousseau JJ; Pfizer Worldwide Research, Development and Medical, Groton, CT, USA., Bull JA; Department of Chemistry, Imperial College London, Molecular Sciences Research Hub, London, UK. j.bull@imperial.ac.uk.
Publikováno v:
Nature chemistry [Nat Chem] 2022 Feb; Vol. 14 (2), pp. 160-169. Date of Electronic Publication: 2022 Jan 27.
Autor:
Nugent J; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom., Sterling AJ; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom., Frank N; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom., Mousseau JJ; Pfizer Worldwide Research and Development, Eastern Point Road, Groton, Connecticut 06340, United States., Anderson EA; Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom.
Publikováno v:
Organic letters [Org Lett] 2021 Nov 05; Vol. 23 (21), pp. 8628-8633. Date of Electronic Publication: 2021 Oct 26.
Autor:
Dubois MAJ; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London Wood Lane London W12 0BZ UK j.bull@imperial.ac.uk., Croft RA; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London Wood Lane London W12 0BZ UK j.bull@imperial.ac.uk., Ding Y; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London Wood Lane London W12 0BZ UK j.bull@imperial.ac.uk., Choi C; Medicine Design, Pfizer Worldwide Research, Development and Medical 445 Eastern Point Rd. Groton CT 06340 USA james.mousseau@haldathera.com., Owen DR; Pfizer Medicine Design 610 Main St Cambridge MA 02139 USA., Bull JA; Department of Chemistry, Molecular Sciences Research Hub, White City Campus, Imperial College London Wood Lane London W12 0BZ UK j.bull@imperial.ac.uk., Mousseau JJ; Medicine Design, Pfizer Worldwide Research, Development and Medical 445 Eastern Point Rd. Groton CT 06340 USA james.mousseau@haldathera.com.
Publikováno v:
RSC medicinal chemistry [RSC Med Chem] 2021 Oct 06; Vol. 12 (12), pp. 2045-2052. Date of Electronic Publication: 2021 Oct 06 (Print Publication: 2021).