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Identification of Human Host Substrates of the SARS-CoV‑2 M^pro and PL^pro Using Subtiligase N‑Terminomics.

Autor: Luo, Shu Y., Moussa, Eman W., Lopez-Orozco, Joaquin, Felix-Lopez, Alberto, Ishida, Ray, Fayad, Nawell, Gomez-Cardona, Erik, Wang, Henry, Wilson, Joyce A., Kumar, Anil, Hobman, Tom C., Julien, Olivier

Publikováno v: ACS Infectious Diseases; 4/14/2023, Vol. 9 Issue 4, p749-761, 13p

Monkeypox virus infection of human astrocytes causes gasdermin B cleavage and pyroptosis.

Autor: Miranzadeh Mahabadi H; Department of Medicine, University of Alberta, Edmonton, AB T5N 2S2, Canada., Lin YCJ; Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, AB T5N 2S2, Canada., Ogando NS; Department of Medicine, University of Alberta, Edmonton, AB T5N 2S2, Canada., Moussa EW; Department of Biochemistry, University of Alberta, Edmonton, AB T5N 2S2, Canada., Mohammadzadeh N; Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, AB T5N 2S2, Canada., Julien O; Department of Biochemistry, University of Alberta, Edmonton, AB T5N 2S2, Canada., Alto NM; Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, TX 75390-8816., Noyce RS; Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, AB T5N 2S2, Canada.; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB T5N 2S2, Canada., Evans DH; Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, AB T5N 2S2, Canada.; Li Ka Shing Institute of Virology, University of Alberta, Edmonton, AB T5N 2S2, Canada., Power C; Department of Medicine, University of Alberta, Edmonton, AB T5N 2S2, Canada.; Department of Medical Microbiology & Immunology, University of Alberta, Edmonton, AB T5N 2S2, Canada.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Feb 20; Vol. 121 (8), pp. e2315653121. Date of Electronic Publication: 2024 Feb 12.