Zobrazeno 1 - 10
of 3 803
pro vyhledávání: '"Mouse Strains"'
Autor:
Maria G. Ledesma-Colunga, Vanessa Passin, Maja Vujic Spasic, Lorenz C. Hofbauer, Ulrike Baschant, Martina Rauner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Iron is an essential nutrient for all living organisms. Both iron deficiency and excess can be harmful. Bone, a highly metabolic active organ, is particularly sensitive to fluctuations in iron levels. In this study, we investigated the effec
Externí odkaz:
https://doaj.org/article/b2489d71ce5a4ab2901d9eeeb41f5e37
Autor:
Olga V. Perepelkina, Inga I. Poletaeva
Publikováno v:
Neurology International, Vol 15, Iss 2, Pp 649-660 (2023)
In this paper, the data are presented concerning different reactions to seven daily injections of atomoxetine in two mouse strains differing in relative brain weight. Atomoxetine affected the performance in a puzzle-box cognitive test in a complicate
Externí odkaz:
https://doaj.org/article/8d35dfe9debc4658ba244ae326a79f31
Autor:
Djamaa Atamena, Venu Gurram, Petnoï Petsophonsakul, Farnoosh Khosrobakhsh, Macarena S. Arrázola, Marlène Botella, Bernd Wissinger, Marion Szelechowski, Pascale Belenguer
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Dominant optic atrophy (DOA) is mainly caused by OPA1 mutations and is characterized by the degeneration of retinal ganglion cells (RGCs), whose axons form the optic nerve. The penetrance of DOA is incomplete and the disease is marked by highly varia
Externí odkaz:
https://doaj.org/article/fee25e707cac4f04b6fc102071611092
Autor:
Wendy W. Yang, Jessica J. Matyas, Yun Li, Hangnoh Lee, Zhuofan Lei, Cynthia L. Renn, Alan I. Faden, Susan G. Dorsey, Junfang Wu
Publikováno v:
Cells, Vol 13, Iss 9, p 759 (2024)
Strain differences have been reported for motor behaviors, and only a subset of spinal cord injury (SCI) patients develop neuropathic pain, implicating genetic or genomic contribution to this condition. Here, we evaluated neuropsychiatric behaviors i
Externí odkaz:
https://doaj.org/article/203884880b32467aa70a941d920b6a2e
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
BackgroundAlcohol use disorder (AUD) is a major problem of our society and is often characterized and worsened by relapse. Prolonged alcohol exposure leads to numerous biochemical alterations that, upon cessation of alcohol intake, cause an array of
Externí odkaz:
https://doaj.org/article/5ccb12d54ea24bc6a28d887c49ec8b02
Autor:
Yujuan Gui, Kamil Grzyb, Mélanie H. Thomas, Jochen Ohnmacht, Pierre Garcia, Manuel Buttini, Alexander Skupin, Thomas Sauter, Lasse Sinkkonen
Publikováno v:
Epigenetics & Chromatin, Vol 14, Iss 1, Pp 1-20 (2021)
Abstract Background Cell types in ventral midbrain are involved in diseases with variable genetic susceptibility, such as Parkinson’s disease and schizophrenia. Many genetic variants affect regulatory regions and alter gene expression in a cell-typ
Externí odkaz:
https://doaj.org/article/e4649b828cf44d01a3390a57108ae561
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Previously the effect of the pruritogens, such as histamine and chloroquine, was tested in 11 inbred mouse strains, and this study aimed to identify resistant and sensitive strains, consistent with the observation that underlies the large variability
Externí odkaz:
https://doaj.org/article/cc28eaa4ce0a4028b9decdfada2e472d
Autor:
Justin Q. Anderson, Priscila Darakjian, Robert Hitzemann, Denesa R. Lockwood, Tamara J. Phillips, Angela R. Ozburn
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
The collaborative cross (CC) founder strains include five classical inbred laboratory strains [129S1/SvlmJ (S129), A/J (AJ), C57BL/6J (B6), NOD/ShiLtJ (NOD), and NZO/HILtJ (NZO)] and three wild-derived strains [CAST/EiJ (CAST), PWK/PhJ (PWK), and WSB
Externí odkaz:
https://doaj.org/article/78e62170347c4b1fb8ce0129ee185874
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-15 (2021)
Abstract Background Genetic variation in a population has an influence on the manifestation of monogenic as well as multifactorial disorders, with the underlying genetic contribution dependent on several interacting variants. Common laboratory mouse
Externí odkaz:
https://doaj.org/article/4c408e32d5e24c1e95c8760c0bbaf7b8