Zobrazeno 1 - 10
of 363
pro vyhledávání: '"Mouse Protein"'
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Liver Kinase B1 (LKB1), encoded by Serine-Threonine Kinase 11 (STK11), is a master kinase that regulates cell migration, polarity, proliferation, and metabolism through downstream adenosine monophosphate-activated protein kinase (AMPK) and A
Externí odkaz:
https://doaj.org/article/177eccc9e3384d40af0f4e11a5e253a0
Publikováno v:
Mathematical Biosciences and Engineering, Vol 19, Iss 4, Pp 3820-3842 (2022)
Protein is very important for almost all living creatures because it participates in most complicated and essential biological processes. Determining the functions of given proteins is one of the most essential problems in protein science. Such deter
Externí odkaz:
https://doaj.org/article/431bebf5e2314bc89248ea036d33f1b0
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
In current biology, exploring the biological functions of proteins is important. Given the large number of proteins in some organisms, exploring their functions one by one through traditional experiments is impossible. Therefore, developing quick and
Externí odkaz:
https://doaj.org/article/07fd579751384632980fc9f813dbcc64
Akademický článek
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Autor:
Ke Ding, Randall K. Mann, Philip A. Beachy, Daniel Asarnow, Qianqian Wang, Yifan Cheng, Jason Hatakeyama, Yunxiao Zhang, Yong Ma
Publikováno v:
Nature. 599:320-324
The Dispatched protein, which is related to the NPC1 and PTCH1 cholesterol transporters1,2 and to H+-driven transporters of the RND family3,4, enables tissue-patterning activity of the lipid-modified Hedgehog protein by releasing it from tightly -loc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d1b8b5e8ceaa9089fe9fae8ec80e4c7
https://doi.org/10.1038/s41586-021-03996-0
https://doi.org/10.1038/s41586-021-03996-0
Autor:
Edgar D. Páez-Pérez, Claudia G. Benítez-Cardoza, Miriam Livier Llamas-García, Samuel Lara-González, Gabriela M. Montero-Morán
Publikováno v:
ACS Omega, Vol 5, Iss 40, Pp 25841-25847 (2020)
ACS Omega
ACS Omega
G0S2 is a small protein of 103 residues in length that is involved in multiple cellular processes. To date, several reports have shown that G0S2 functions by making direct protein–protein interactions with key proteins. In lipolysis, G0S2 specifica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b33e930324a1c0bc040c9104230323
https://doaj.org/article/959f7c3b12954f5dba7930a693f95e20
https://doaj.org/article/959f7c3b12954f5dba7930a693f95e20
Publikováno v:
Faculty Reviews
Huntington’s disease (HD) is a neurodegenerative disease that results in motor and cognitive dysfunction, leading to early death. HD is caused by an expansion of CAG repeats in the huntingtin gene (HTT). Here, we review the mouse models of HD. They
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ec8ee6da4eb72ce3450d6b738f79d5
https://pubmed.ncbi.nlm.nih.gov/34746930
https://pubmed.ncbi.nlm.nih.gov/34746930
Autor:
Ana Martinez Hernandez, Ivan Silbern, Insa Geffers, Lars Tatenhorst, Stefan Becker, Henning Urlaub, Markus Zweckstetter, Christian Griesinger, Gregor Eichele
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in neuroscience 15, 643391 (2021). doi:10.3389/fnins.2021.643391
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in neuroscience 15, 643391 (2021). doi:10.3389/fnins.2021.643391
α-synuclein (αSyn) is the main protein component of Lewy bodies, intracellular inclusions found in the brain of Parkinson’s disease (PD) patients. Neurotoxic αSyn species are broadly modified post-translationally and, in patients with genetic fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6964a821fd939058edfcaa9ad39b9242
Publikováno v:
Biochemical and Biophysical Research Communications. 519:832-837
Lecithin retinol acyltransferase (LRAT) is involved in the visual cycle where it catalyzes the formation of all-trans retinyl ester. The mouse animal model has been widely used to study LRAT. Primary sequence alignment shows 80% identity and 90% simi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cd430ed6ca9ca348422acea3ec6f66
https://doi.org/10.1016/j.bbrc.2019.09.061
https://doi.org/10.1016/j.bbrc.2019.09.061
Publikováno v:
Journal of Molecular and Cellular Cardiology. 125:140-148
Rationale Mutations in the gene encoding the sarcomeric protein cardiac myosin-binding protein C (cMyBP-C) are a leading cause of hypertrophic cardiomyopathy (HCM). Mouse models targeting cMyBP-C and use of recombinant proteins have been effective in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b41d815fc6ee7754ab5e12bb427c4e
https://doi.org/10.1016/j.yjmcc.2018.10.009
https://doi.org/10.1016/j.yjmcc.2018.10.009