Critical Roles of E2F3 in Growth and Musculo-skeletal Phenotype in Mice

Autor: Kwang Soo Kim, Won Kee Yoon, Eun-Kyeung Kim, Ok Sung Moon, Ho-Young Kang, Hyoung-Chin Kim, Young Won Seo, Faiz Ur Rahman, Young Suk Won, Ki Hoan Nam, Ki Hoon Lee, Sang-Mi Cho, Hae-Rim Kim

Publikováno v: International Journal of Medical Sciences

E2F3, a member of the E2F family, plays a critical role in cell cycle and proliferation by targeting downstream, retinoblastoma (RB) a tumor suppressor family protein. The purpose of this study, was to investigate the role and function of E2F3 in viv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda5e85d7f15aa0070cad963a1969332
http://europepmc.org/articles/PMC6909802

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The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase*

Autor: Ten Feizi, Janet A. Willment, Matti Kimberg, Gordon D. Brown, María Asunción Campanero-Rhodes, Peter Sobieszczuk, Angelina S. Palma, Vandana Gupta, William G. Hornsell, Stella K. Kim, Kevin M. Dennehy, Lisa M. Graham, Reto Guler, Georgia Schäfer, Delyth M. Reid

Publikováno v: The Journal of Biological Chemistry
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname

11 pags, 7 figs
CLECSF8 is a poorly characterized member of the "Dectin-2 cluster" of C-type lectin receptors and was originally thought to be expressed exclusively by macrophages. We show here that CLECSF8 is primarily expressed by peripheral b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26ce17f5889dfdcc1444c68d77fd667
http://europepmc.org/articles/PMC3406680

BioMedBridges pilot life science data integration using rest web services

Autor: Belien, Jeroen, Birney, Ewan, Boiten, Jan-Willem, Brasch, Benjamin, Brunner, Sabine, Chambers, Jon, Faulconbridge, Adam, Gormanns, Philipp, Halim, Safey, Hendriksen, Ison, Karakoyun, Toeresin, Maier, Holger, Mann, Willi, McMurry, Julie, Morris, Chris, Ohmann, Christian, Overington, John, Parkinson, Helen, Steinkamp, Ralph, Swertz, Morris, Winn, Martyn

The report describes six pilot integration studies which span the BioMedBridges domains and which will act as drivers for future data integration activities: Pilot 1 (Biosample information integration and discovery) integrated two pivotal resources b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a5e79341052b96cf1950d690e655a23

Computational Selection and Prioritization of Disease Candidate Genes

Autor: Chen, Jing

Identifying causal genes underlying susceptibility to human disease is a problem of primary importance in post-genomic era and current biomedical research. Recently, there has been a paradigm shift of such gene-discovery efforts from rare, monogenic

Externí odkaz: http://rave.ohiolink.edu/etdc/view?acc_num=ucin1211228557