Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Mouse Gastrointestinal Tract"'
Autor:
Alejandro Chavez, Marcelle Tuttle, Brian M. Turczyk, George M. Church, Benjamin W. Pruitt, Michael Tung, Rebecca S. Shapiro, Jordan Winston, Ryan J Cecchi, James J. Collins
Publikováno v:
Proceedings of the National Academy of Sciences. 115:3669-3673
Here, we present a generalized method of guide RNA "tuning" that enables Cas9 to discriminate between two target sites that differ by a single-nucleotide polymorphism. We employ our methodology to generate an in vivo mutation prevention system in whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6830f1e868e12c6a3c59fbb38e5469f
https://doi.org/10.1073/pnas.1718148115
https://doi.org/10.1073/pnas.1718148115
Autor:
Bin Feng
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 553-554 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Functional interactions between the mu opioid receptor (MOR) and delta opioid receptor (DOR) represent a potential target for novel analgesics and may drive the effects of the clinically approved drug eluxadoline for the treatment o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78978f3a34779f091332aa2257c1ec3
https://doi.org/10.1016/j.jcmgh.2020.01.001
https://doi.org/10.1016/j.jcmgh.2020.01.001
Autor:
Gianrico Farrugia, Peter R. Strege, Amelia Mazzone, Gary E. Shull, Maria Gabriela Colmenares Aguilar, Simon J. Gibbons, Lei Sha, Wenchang Zhao, Seth T. Eisenman, Michael F. Romero
Publikováno v:
The FASEB Journal. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f9d8ea751e3f7195c730a15d155e5af
https://doi.org/10.1096/fasebj.2019.33.1_supplement.544.8
https://doi.org/10.1096/fasebj.2019.33.1_supplement.544.8
Autor:
Andrew J. Gasparrini, Xiaoqing Sun, Stephen Dobrowolski, Aura Ferreiro, Nathan Crook, Zevin Condiotte, Mitchell W. Pesesky, Molly K. Gibson, Bin Wang, Daniel A. Peterson, Gautam Dantas
Summary Probiotics are living microorganisms that are increasingly used as gastrointestinal therapeutics by virtue of their innate or engineered genetic function. Unlike abiotic therapeutics, probiotics can replicate in their intended site, subjectin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad4cb05df61ba6bab58684298479fee
https://europepmc.org/articles/PMC6487504/
https://europepmc.org/articles/PMC6487504/
Autor:
Ryan J Cecchi, Rebecca S. Shapiro, James J. Collins, Jordan Winston, Alejandro Chavez, Marcelle Tuttle, Michael Tung, George M. Church, Benjamin W. Pruitt, Brian M. Turczyk
Here we present a generalized method of guide RNA “tuning” that enables Cas9 to discriminate between two target sites that differ by a single nucleotide polymorphism. We employ our methodology to generate a novelin vivomutation prevention system
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fafedb990d1ca634964d9d8ee7120c53
Autor:
Piard, J.C., Briandet, Romain
Publikováno v:
Biotechnology of Lactic Acid Bacteria
Biotechnology of Lactic Acid Bacteria, John Wiley & Sons, Ltd, 2016, 978-1-118-86837-9 ; 978-1-118-86840-9. ⟨10.1002/9781118868386⟩
Biotechnology of Lactic Acid Bacteria, John Wiley & Sons, Ltd, 2016, 978-1-118-86837-9 ; 978-1-118-86840-9. ⟨10.1002/9781118868386⟩
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::26802e0faed0ba3c69ce40f70a1b31e4
https://hal.inrae.fr/hal-03033919
https://hal.inrae.fr/hal-03033919
Autor:
Amanda Maree Walmsley, Robert Shepherd, John D. Hamill, Giorgio De Guzman, Assunta Pelosi, Elza Nicole Theresia Meeusen, Gordon Drummond Sanson
Publikováno v:
Current Drug Delivery. 8:612-621
This study investigated the site of release of a model vaccine antigen from plant cells and the corresponding induced immune response. Three plant tissues (leaf, fruit and hairy root) and two formulations (aqueous and lipid) were compared in two mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::907c82e3e9a4b9b9ee53feb06dee245d
https://doi.org/10.2174/156720111797635513
https://doi.org/10.2174/156720111797635513
Autor:
G. Webb McKnight, Michael Dicay, Gary R. Martin, John L. Wallace, Jose G. Ferraz, Carla S. Coffin
Publikováno v:
Digestive and Liver Disease. 42:103-109
Hydrogen sulphide (H2S) exerts several anti-inflammatory effects, accelerates the healing of experimental gastric ulcers, and can stimulate intestinal secretion. Little is known about H2S synthesis in the gastrointestinal tract. The aim of this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::576ab7dae6f384f783b683c434a81ba8
https://doi.org/10.1016/j.dld.2009.05.016
https://doi.org/10.1016/j.dld.2009.05.016
Publikováno v:
Journal of the Neurological Sciences. 381:67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55ac0ed1011e959abc790e09d024f40e
https://doi.org/10.1016/j.jns.2017.08.244
https://doi.org/10.1016/j.jns.2017.08.244
Publikováno v:
Molecular Microbiology 59 (2006) 6
Molecular Microbiology, 59(6), 1639-1650
Molecular Microbiology, 59(6), 1639-1650
The microbial world within us includes a vast array of gastrointestinal (GI) tract communities that play an important role in health and disease. Significant progress has been made in recent years in describing the intestinal microbial composition ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830fdc6d6c3c2e765b704fd96144adcd
https://research.wur.nl/en/publications/a-microbial-world-within-us
https://research.wur.nl/en/publications/a-microbial-world-within-us