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Up-regulation of miR-381 inhibits NAD+ salvage pathway and promotes apoptosis in breast cancer cells
Autor:
Bolandghamat Pour, Zahra, Nourbakhsh, Mitra, Mousavidzadeh, Kazem, Madjd, Zahra, Ghorbanhosseini, Seyedeh Sara, Abdolvahabi, Zohreh, Hesari, Zahra, Mobaser, Samira Ezzati
Publikováno v:
EXCLI Journal
Nicotinamide phosphoribosyltransferase (NAMPT), a rate-limiting enzyme involved in nicotinamide adenine di- nucleotide (NAD) salvage pathway, is overexpressed in many human malignancies such as breast cancer. This enzyme plays a critical role in surv