FlowAtlas: an interactive tool for high-dimensional immunophenotyping analysis bridging FlowJo with computational tools in Julia.

Autor: Coppard V; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Szep G; Randall Centre for Cell & Molecular Biophysics, King's College London, London, United Kingdom., Georgieva Z; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Howlett SK; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Jarvis LB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Rainbow DB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Suchanek O; Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Needham EJ; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Mousa HS; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom., Menon DK; Department of Anaesthesia, University of Cambridge, Cambridge, United Kingdom., Feyertag F; Independent Researcher, Oxford, United Kingdom., Mahbubani KT; Department of Surgery, University of Cambridge, Cambridge, United Kingdom.; Collaborative Biorepository for Translational Medicine (CBTM), Cambridge NIHR Biomedical Research Centre, Cambridge, United Kingdom., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge, United Kingdom.; Collaborative Biorepository for Translational Medicine (CBTM), Cambridge NIHR Biomedical Research Centre, Cambridge, United Kingdom., Jones JL; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom.

Publikováno v: Frontiers in immunology [Front Immunol] 2024 Jul 17; Vol. 15, pp. 1425488. Date of Electronic Publication: 2024 Jul 17 (Print Publication: 2024).

Captopril Polyvinyl Alcohol/Sodium Alginate/Gelatin-Based Oral Dispersible Films (ODFs) with Modified Release and Advanced Oral Bioavailability for the Treatment of Pediatric Hypertension.

Autor: Abdelkader H; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 62223, Saudi Arabia., Abdel-Aleem JA; Department of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt., Mousa HS; Pharmaceutical Analytical Chemistry Department, Faculty of Pharmacy, South Valley University, Qena 83523, Egypt., Elgendy MO; Department of Clinical Pharmacy, Beni-Suef University Hospitals, Faculty of Medicine, Beni-Suef University, Beni Suef 62521, Egypt.; Department of Clinical Pharmacy, Faculty of Pharmacy, Nahda University (NUB), Beni Suef 62521, Egypt., Al Fatease A; Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha 62223, Saudi Arabia., Abou-Taleb HA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Merit University, Sohag 82755, Egypt.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2023 Sep 19; Vol. 16 (9). Date of Electronic Publication: 2023 Sep 19.

Cross-tissue immune cell analysis reveals tissue-specific features in humans.

Autor: Domínguez Conde C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Xu C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Jarvis LB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Rainbow DB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Wells SB; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Gomes T; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Howlett SK; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Suchanek O; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK., Polanski K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., King HW; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK., Mamanova L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Huang N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Szabo PA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Richardson L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Bolt L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Fasouli ES; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Mahbubani KT; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Prete M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Tuck L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Richoz N; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK., Tuong ZK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK., Campos L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; West Suffolk Hospital NHS Trust, Bury Saint Edmunds, UK., Mousa HS; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Needham EJ; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Pritchard S; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Li T; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Elmentaite R; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Park J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Rahmani E; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, USA., Chen D; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Menon DK; Department of Anaesthesia, University of Cambridge, Cambridge, UK., Bayraktar OA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., James LK; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK., Meyer KB; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK., Yosef N; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA., Clatworthy MR; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK., Sims PA; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA., Farber DL; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA., Saeb-Parsy K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK., Jones JL; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.; Theory of Condensed Matter, Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, UK.

Publikováno v: Science (New York, N.Y.) [Science] 2022 May 13; Vol. 376 (6594), pp. eabl5197. Date of Electronic Publication: 2022 May 13.

A method to isolate and cryopreserve cerebrospinal fluid mononuclear cells from external ventricular drains to investigate immunological processes in acute brain injuries.

Autor: Digby RJ; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK., Coppard V; Department of Clinical Neurosciences, University of Cambridge, UK., Mousa HS; Department of Clinical Neurosciences, University of Cambridge, UK., Menon DK; Division of Anaesthesia, Department of Medicine, University of Cambridge, UK., Coles AJ; Department of Clinical Neurosciences, University of Cambridge, UK., Jones JL; Department of Clinical Neurosciences, University of Cambridge, UK., Needham EJ; Department of Clinical Neurosciences, University of Cambridge, UK. Electronic address: edneedham@doctors.org.uk.

Publikováno v: Journal of immunological methods [J Immunol Methods] 2021 Dec; Vol. 499, pp. 113163. Date of Electronic Publication: 2021 Oct 02.

Therapeutically expanded human regulatory T-cells are super-suppressive due to HIF1A induced expression of CD73.

Autor: Jarvis LB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Rainbow DB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Coppard V; Department of Medicine, University of Cambridge, Cambridge, UK., Howlett SK; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Georgieva Z; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Davies JL; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Mullay HK; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Hester J; Department of Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Ashmore T; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK., Van Den Bosch A; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Grist JT; Department of Radiology, University of Cambridge, Cambridge, UK., Coles AJ; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Mousa HS; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Pluchino S; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Mahbubani KT; Department of Surgery, University of Cambridge, Cambridge, UK., Griffin JL; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, Cambridge, UK.; Imperial College London Dementia Research Institute & Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge, UK., Issa F; Department of Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Peruzzotti-Jametti L; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Wicker LS; JDRF/Wellcome Diabetes and Inflammation Laboratory, Wellcome Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK., Jones JL; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK. jls53@medschl.cam.ac.uk.

Publikováno v: Communications biology [Commun Biol] 2021 Oct 14; Vol. 4 (1), pp. 1186. Date of Electronic Publication: 2021 Oct 14.