Proliferation in Postmenopausal Endometrial Polyps—A Potential for Malignant Transformation

Autor: Lina Adomaitienė, Rūta Nadišauskienė, Mahshid Nickkho-Amiry, Arvydas Čižauskas, Jolita Palubinskienė, Cathrine Holland, Mourad W Seif

Publikováno v: Medicina, Vol 55, Iss 9, p 543 (2019)

Background and objectives: Endometrial polyps in asymptomatic postmenopausal women are often incidentally found, yet only 1.51% of them are malignant. Their potential for malignant transformation has not been adequately addressed. The aim of this stu

Externí odkaz: https://doaj.org/article/1d6b07f03ff540d9b5a7bc080adc0b25

Lynch syndrome for the gynaecologist

Autor: Mourad W. Seif, Neil A J Ryan, Neal C Ramchander, Raymond Mcmahon, Emma J Crosbie, D. Gareth Evans

Publikováno v: The Obstetrician & Gynaecologist
Ryan, N, McMahon, R, Ramchander, N, Seif, M W, Evans, D G & Crosbie, E 2020, ' Lynch syndrome for the gynaecologist ', The Obstetrician and Gynaecologist . https://doi.org/10.1111/tog.12706

Key content Lynch syndrome is an autosomal dominant condition closely associated with colorectal, endometrial and ovarian cancer.Women with Lynch syndrome are at increased risk of both endometrial and ovarian cancer and should be offered personalised

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d4ba0c87677a1406c6d71f1a7d36d5
https://doi.org/10.1111/tog.12706

Ovarian cancer population screening and mortality after long-term follow-up in the UK collaborative trial of ovarian cancer screening (UKCTOCS): a randomised controlled trial

Autor: Laura Casey, Alistair McGuire, Susan K. Massingham, Mourad W Seif, Stephen Dobbs, Steven J. Skates, Tim Mould, Yiling Liu, Robert Woolas, Stuart Campbell, Andy Ryan, Mahesh K.B. Parmar, Giulia Carlino, Maria Raikou, Ranjit Manchanda, Aarti Sharma, Anne Dawnay, Naveena Singh, Simon Leeson, Karin Williamson, Jatinderpal Kalsi, Usha Menon, Julie Taylor, Aleksandra Gentry-Maharaj, Ian Jacobs, Matthew Burnell, Lesley Fallowfield, Rupali Arora, Chloe Karpinskyj

Ovarian cancer is most commonly diagnosed at an advanced stage (3 or 4) and remains the deadliest gynecologic malignancy. When diagnosed at stage 1, a survival rate of greater than 90% has been demonstrated, compared with a 5-year survival rate of 27

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1315b7d46c8eb010258cd3b463125c5
http://eprints.lse.ac.uk/112982/

Obesity in adolescence

Autor: Gail Busby, Mourad W. Seif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4af53377f47e46e1dfabeb1a7650d899
https://doi.org/10.1016/b978-0-12-817919-2.00002-4

The Manchester International Consensus Group Recommendations for the Management of Gynecological Cancers in Lynch Syndrome

Autor: Emma J. Crosbie, Neil A.J. Ryan, Mark J. Arends, Tjalling Bosse, John Burn, Joanna M. Cornes, Robin Crawford, Diana Eccles, Ian M. Frayling, Sadaf Ghaem-Maghami, Heather Hampel, Noah D. Kauff, Henry C. Kitchener, Sarah J. Kitson, Ranjit Manchanda, Raymond F.T. McMahon, Kevin J. Monahan, Usha Menon, Pål Møller, Gabriela Möslein, Adam Rosenthal, Peter Sasieni, Mourad W. Seif, Naveena Singh, Pauline Skarrott, Tristan M. Snowsill, Robert Steele, Marc Tischkowitz, Angel Alonso Sanchez, James Bolton, David Church, Karen Donnelly, Richard J. Edmondson, D. Gareth Evans, Paula Gollop, Selina Goodman, Shirley Hodgson, Fiona Lalloo, Anne Lowry, Rhona J. McVey, Tracie Miles, Gabriela Moeslein, Pal Moller, Astrid Stormoken, Helen Stringfellow, Andrew Wallace, Luciya Whyte, Nafisa Wilkinson, Godfrey Wilson, Jo Wilson, Nick Wood

Publikováno v: Crosbie, E J, Ryan, N A J, Arends, M, Bosse, T, Burn, J, Cornes, J M, Crawford, R A F, Eccles, D, Frayling, I M, Ghaem-Maghami, S, Hampel, H, Kauff, N, Kitchener, H C, Kitson, S J, Manchanda, R, McMahon, R F T, Monahan, K J, Menon, U, Moller, P, Moeslein, G, Rosenthal, A N, Sasieni, P, Seif, M W, Singh, N, Skarrott, P, Snowsill, T M, Steele, R J, Tischkowitz, M D & Evans, D G R 2019, ' The Manchester International Consensus Group Recommendations for the Management of Gynecological Cancers in Lynch Syndrome ', Genetics in Medicine . https://doi.org/10.1038/s41436-019-0489-y
2019, ' The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome ', Genetics in Medicine, vol. 21, no. 10, pp. 2390-2400 . https://doi.org/10.1038/s41436-019-0489-y
Genetics in Medicine, 21(10), 2390-2400
Crosbie, E, Ryan, N, Evans, D G, Edmondson, R & et al. 2019, ' The Manchester International Consensus Group Recommendations for the Management of Gynecological Cancers in Lynch Syndrome ', Genetics in Medicine . https://doi.org/10.1038/s41436-019-0489-y, https://doi.org/10.1038/s41436-019-0489-y
Genetics in Medicine

Purpose\ud \ud There are no internationally agreed upon clinical guidelines as to which women with gynecological cancer would benefit from Lynch syndrome screening or how best to manage the risk of gynecological cancer in women with Lynch syndrome. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c7e9487cd34eb3fce7e6806ba0cdc3
https://www.pure.ed.ac.uk/ws/files/80507445/The_Manchester_International_Consensus_Group_Recommendations_for_the_Management_of_Gynecological_Cancers_in_Lynch_Syndrome.pdf