Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Mourad Kaghad"'
Autor:
Pierre Dieu, Mourad Kaghad, Annette Roasio, Nathalie Hasel, Amélie Aries, Stéphane Yvon, Jan H. Lupker, Fréderique Guette, Constantino Diaz, Pascual Ferrara, Brigitte Miloux, Claude Feuillerat, Edgardo A. Ferrán, Danielle Albène, Christine Labit-Le Bouteiller, Aimée Cambon-Kernëis, Eric Perret, Marie-Françoise Jamme
Publikováno v:
Molecular Informatics. 32:213-229
The DLS-VS strategy was developed as an integrated method for identifying chemical modulators for orphan GPCRs. It combines differential low-throughput screening (DLS) and virtual screening (VS). The two cascaded techniques offer complementary advant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e85cf33c32baaf7a33295d515bf16a6
https://doi.org/10.1002/minf.201200047
https://doi.org/10.1002/minf.201200047
Autor:
Olivier Hartmann, Daniel Caput, Jean Bénard, Ute M. Moll, David Goldschneider, Sétha Douc-Rasy, Etienne Blanc, Mourad Kaghad, Michel Barrois, Maria Echeynne, Gilda Raguénez, Marie-José Terrier-Lacombe
Publikováno v:
The American Journal of Pathology. 160:631-639
Neuroblastic tumors (NTs), occurring in early childhood, display a wide spectrum of differentiation. Recurrent deletions involving the p73 locus are frequently observed in undifferentiated NTs. To address the question of the possible implication of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5140fd25c1c2f620fb4a30d03ba970cb
https://doi.org/10.1016/s0002-9440(10)64883-3
https://doi.org/10.1016/s0002-9440(10)64883-3
Autor:
Marie‐Luce Le Bihan, Muriel Vayssade, Jean-Charles Ahomadegbe, Daniel Caput, Jacques Bosq, Laetitia Faridoni-Laurens, Mourad Kaghad, Jean Bénard, François Janot
Publikováno v:
Oncogene. 20:5302-5312
P73, a p53-homologue gene, has been studied for its possible role in head and neck squamous epithelium (HNSE) differentiation and carcinogenesis. P73 RNA and protein were analysed in 50 biopsies, including well- and moderately-differentiated carcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c17db91071b267e4cf5d06737cb350ce
https://doi.org/10.1038/sj.onc.1204687
https://doi.org/10.1038/sj.onc.1204687
Publikováno v:
Journal of Biological Chemistry. 275:36316-36323
Two-hybrid screening in yeast with p73alpha isolated SUMO-1 (small ubiquitin-like modifier 1), the enzyme responsible for its conjugation, Ubc-9, and a number of novel SUMO-1-interacting proteins, including thymine DNA glycosylase, PM-Scl75, PIASx, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe12bcb1a99764f5210b0a6b90f3ed39
https://doi.org/10.1074/jbc.m004293200
https://doi.org/10.1074/jbc.m004293200
Autor:
Arlene H. Sharpe, Daniel Caput, Annie Yang, Clifford J. Tabin, Roderick T. Bronson, Mourad Kaghad, Nancy Walker, Christopher P. Crum, Deqin Sun, Ronen Schweitzer, Frank McKeon
Publikováno v:
Nature. 398:714-718
The p63 gene, a homologue of the tumour-suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. Here we report that mice homozygous for a disrupted p63 gene have major defects in their limb, craniofacial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff8033cc3a0f827a404429dfd7d471c
https://doi.org/10.1038/19539
https://doi.org/10.1038/19539
Autor:
Volker Dötsch, Annie Yang, Emily Gillett, Mourad Kaghad, Yunmei Wang, Daniel Caput, Frank McKeon, Nancy C. Andrews, Mark D. Fleming
Publikováno v:
Scopus-Elsevier
We describe the cloning of p63, a gene at chromosome 3q27-29 that bears strong homology to the tumor suppressor p53 and to the related gene, p73. p63 was detected in a variety of human and mouse tissues, including proliferating basal cells of epithel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659aa3c6bc665d3285933be174c3751b
Publikováno v:
FEMS Microbiology Letters. 159:331-336
A 7.275-kb DNA fragment which encodes resistance by abortive infection (Abi+) to bacteriophage was cloned from Lactococcus lactis subsp. cremoris S114. The genetic determinant for abortive infection was subcloned from this fragment. This gene was fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29ff3530e1db3597efbc568d22327443
https://doi.org/10.1111/j.1574-6968.1998.tb12879.x
https://doi.org/10.1111/j.1574-6968.1998.tb12879.x
Autor:
Adrian Minty, Mourad Kaghad, Xavier Dumont, Pascual Ferrara, Frank McKeon, Jean-Michel Lelias, A. Valent, Helene Bonnet, Laurent Creancier, Jean-Christophe Biscan, Annie Yang, Pascale Chalon, Daniel Caput
Publikováno v:
Cell. 90(4):809-819
We describe a gene encoding p73, a protein that shares considerable homology with the tumor suppressor p53. p73 maps to 1p36, a region frequently deleted in neuroblastoma and other tumors and thought to contain multiple tumor suppressor genes. Our an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::430a36c26424acb019070f28d1ca573e
Autor:
Daniel Caput, S. Lefort, Natalio Vita, Pascual Ferrara, Patrick Laurent, Jean-Michel Lelias, Mourad Kaghad
Publikováno v:
Journal of Biological Chemistry. 271:16921-16926
Interleukin-13 (IL-13) is a cytokine secreted by activated T lymphocytes that shares many, but not all, biological activities with IL-4. These overlapping activities are probably due to the existence of common receptor components. Two proteins have b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b816c5516a27ca8562d2b7e16efa70
https://doi.org/10.1074/jbc.271.28.16921
https://doi.org/10.1074/jbc.271.28.16921
Autor:
Daniel Caput, G Le Fur, A Rahier, Mourad Kaghad, C Lanau, P.-H. Dupuy, M Taton, Gérard Loison, Claudine Picard, A Josse, Pascal Leplatois, P. Ferrara, C Dhers, Sandra Silve
Publikováno v:
Molecular and Cellular Biology. 16:2719-2727
SR 31747 is a novel immunosuppressant agent that arrests cell proliferation in the yeast Saccharomyces cerevisiae, SR 31747-treated cells accumulate the same aberrant sterols as those found in a mutant impaired in delta 8- delta 7-sterol isomerase. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa631b033e2e65ee81e099770a0fbd09
https://doi.org/10.1128/mcb.16.6.2719
https://doi.org/10.1128/mcb.16.6.2719