Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mouna Lagraoui"'
Autor:
Brian C. Schaefer, Mouna Lagraoui, Clifton L. Dalgard, Joseph R. Latoche, Gauthaman Sukumar, Sean K. Maynard
Publikováno v:
Brain, behavior, and immunity. 61
Neuroinflammation plays a critical role in the pathogenesis of traumatic brain injury (TBI). TBI induces rapid activation of astrocytes and microglia, infiltration of peripheral leukocytes, and secretion of inflammatory cytokines. In the context of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10351298bede7b4c1ebd16f5ecebaf5c
https://pubmed.ncbi.nlm.nih.gov/27939247
https://pubmed.ncbi.nlm.nih.gov/27939247
Publikováno v:
The Journal of Immunology. 169:393-398
Mice lacking the gene for the IL-1R antagonist (IL-1ra) show abnormal development and homeostasis as well as altered responses to infectious and inflammatory stimuli. A reduction in the level of IL-1 signaling, either by deletion of the receptor or i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc5ce3fd84241f3067f45db8db1461f
https://doi.org/10.4049/jimmunol.169.1.393
https://doi.org/10.4049/jimmunol.169.1.393
Autor:
Mouna Lagraoui, Corey A. Carter, Clifton L. Dalgard, Celeste Huaman, Brian C. Schaefer, Thomas A. Summers, Gauthaman Sukumar
Publikováno v:
Cancer Research. 77:4000-4000
Tumorigenesis is accompanied by broad changes to the surrounding tissue microenvironment in a tumor- and patient-specific manner. Phenotype shifts in tissue-resident immune cells promote cancer progression by establishing a proliferative inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f59e849960ac25e4db86a623aef05f5e
https://doi.org/10.1158/1538-7445.am2017-4000
https://doi.org/10.1158/1538-7445.am2017-4000
Autor:
Gauthaman Sukumar, Clifton L. Dalgard, Mouna Lagraoui, Brian C. Schaefer, Celeste Huaman, Corey A. Carter
Publikováno v:
Cancer Research. 77:2939-2939
Tumorigenesis is modified by dynamic activities in the tumor microenvironment and mechanisms driving these alterations during tumor progression may be tumor- and patient-specific. Of well-established functions for tumor-associated stromal cells (e.g.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31b12eb06cb11d88fbdc7c8df31140b1
https://doi.org/10.1158/1538-7445.am2017-2939
https://doi.org/10.1158/1538-7445.am2017-2939
Publikováno v:
Journal of Medicinal Chemistry. 42:2046-2052
Imreg (Tyr1-Gly2-Gly3) is a well-known immunostimulant. However, it possesses a short half-life. Stabilized analogues of Imreg were prepared by a regioselective insertion in which peptide bonds at position 1,2 or 2,3 were replaced by thioamide linkag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d76f7fd34da0618d1a71af6332a5cdb
https://doi.org/10.1021/jm9900467
https://doi.org/10.1021/jm9900467
Autor:
Natalia G. Cartwright, Clifton L. Dalgard, Gauthaman Sukumar, Joseph R. Latoche, Mouna Lagraoui, Brian C. Schaefer
Publikováno v:
Frontiers in Neurology, Vol 3 (2012)
Frontiers in Neurology
Frontiers in Neurology
An immediate consequence of traumatic brain injury (TBI) is the induction of an inflammatory response. Mounting data suggest that inflammation is a major contributor to TBI-induced brain damage. However, much remains unknown regarding the induction a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f4c8825f457b4962c2fd8b2ae88d816
http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00155/full
http://journal.frontiersin.org/Journal/10.3389/fneur.2012.00155/full
Publikováno v:
ChemInform. 30
Imreg (Tyr1-Gly2-Gly3) is a well-known immunostimulant. However, it possesses a short half-life. Stabilized analogues of Imreg were prepared by a regioselective insertion in which peptide bonds at position 1,2 or 2,3 were replaced by thioamide linkag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82a5dcda215b0d569af3259b040ca399
https://doi.org/10.1002/chin.199938188
https://doi.org/10.1002/chin.199938188
Autor:
Shaun D. Abbott, Boulos Zacharie, Giorgio Attardo, Lyne Gagnon, Christopher Penney, Salam Kadhim, Mouna Lagraoui
Publikováno v:
Journal of medicinal chemistry. 41(11)
Water soluble analogues of the lipophilic immunostimulant, octadecyl D-alanyl-L-glutamine, BCH-527, were synthesized and evaluated for the ability to stimulate natural killer (NK) cells. One of these compounds in which the octadecyl chain of BCH-527
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed5f2e12dc8232f81c1baf7556f4f2c
https://pubmed.ncbi.nlm.nih.gov/9599240
https://pubmed.ncbi.nlm.nih.gov/9599240
Autor:
Lyne Gagnon, Mouna Lagraoui, Kathy Hince, François Sarra-Bournet, Brigitte Grouix, Lilianne Geerts, Pierre Laurin, Christopher Penney
Publikováno v:
Cancer Research. 71:672-672
BACKGROUND: PBI-1402 reduces the need for transfusion and increases hemoglobin (Hb) level and red blood cell count (RBC) in chemotherapy-induced anemia (CIA) by a mechanism of action distinct from erythropoietin (EPO). AIM: The objective was to compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd69fde3645fbf20e0786ce37dbf9d67
https://doi.org/10.1158/1538-7445.am2011-672
https://doi.org/10.1158/1538-7445.am2011-672
Autor:
Marie-Eve Fafard, Lyne Gagnon, Christopher Penney, François Sarra-Bournet, Kathy Hince, Liette Gervais, Brigitte Grouix, Pierre Laurin, Mouna Lagraoui, Lilianne Geerts, Nathalie Julien
Publikováno v:
Cancer Research. 71:3534-3534
Background: PBI-1402 reduces the need for transfusion and increases hemoglobin (Hb) level and red blood cell count (RBC) in chemotherapy-induced anemia (CIA) patients by a mechanism of action which is distinct from erythropoietin (EPO). The PBI-1402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::599337d4daf6fce444352ea149f775c2
https://doi.org/10.1158/1538-7445.am2011-3534
https://doi.org/10.1158/1538-7445.am2011-3534