A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer.

Autor: Mayoh C; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia.; University of New South Wales Centre for Childhood Cancer Research, UNSW, Kensington, NSW, Australia., Gifford AJ; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia.; Anatomical Pathology, NSW Health Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Terry R; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia., Lau LMS; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Wong M; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia., Rao P; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia., Shai-Hee T; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia., Saletta F; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia., Khuong-Quang DA; Children's Cancer Centre, Royal Children's Hospital, Parkville, VIC, Australia.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia., Qin V; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Mateos MK; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Meyran D; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Miller KE; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA., Yuksel A; Tumour Bank, Children's Hospital Westmead, Westmead, NSW, Australia., Mould EVA; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia., Bowen-James R; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Computer Science and Engineering, UNSW Sydney, Kensington, NSW, Australia.; School of Biomedical Engineering, UNSW Sydney, Kensington, NSW, Australia., Govender D; Cancer Centre for Children, Children's Hospital Westmead, Westmead, NSW, Australia., Senapati A; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Zhukova N; Monash Children's Hospital, Melbourne, VIC, Australia.; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Paediatrics, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Omer N; Oncology Service, Children's Health Queensland Hospital & Health Service, Brisbane, QLD, Australia.; The University of Queensland Frazer Institute, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., Dholaria H; Department of Paediatric and Adolescent Oncology and Haematology, Perth Children's Hospital, Nedlands, WA, Australia.; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA, Australia., Alvaro F; John Hunter Children's Hospital, New Lambton Heights, NSW, Australia., Tapp H; Michael Rice Cancer Centre, Women's and Children's Hospital, South Australia Health and Medical Research Institute, Adelaide, SA, Australia., Diamond Y; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia.; Children's Cancer Centre, Royal Children's Hospital, Parkville, VIC, Australia., Pozza LD; Cancer Centre for Children, Children's Hospital Westmead, Westmead, NSW, Australia., Moore AS; Oncology Service, Children's Health Queensland Hospital & Health Service, Brisbane, QLD, Australia.; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia., Nicholls W; Oncology Service, Children's Health Queensland Hospital & Health Service, Brisbane, QLD, Australia.; School of Medicine, The University of Queensland, Brisbane, QLD, Australia., Gottardo NG; Department of Paediatric and Adolescent Oncology and Haematology, Perth Children's Hospital, Nedlands, WA, Australia.; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA, Australia., McCowage G; Cancer Centre for Children, Children's Hospital Westmead, Westmead, NSW, Australia., Hansford JR; Michael Rice Cancer Centre, Women's and Children's Hospital, South Australia Health and Medical Research Institute, Adelaide, SA, Australia.; South Australia ImmunoGENomics Cancer Institute, University of Adelaide, Adelaide, SA, Australia., Khaw SL; Children's Cancer Centre, Royal Children's Hospital, Parkville, VIC, Australia.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia., Wood PJ; Monash Children's Hospital, Melbourne, VIC, Australia.; Centre for Cancer Research, Hudson Institute of Medical Research, Clayton, VIC, Australia.; Department of Paediatrics, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Catchpoole D; Tumour Bank, Children's Hospital Westmead, Westmead, NSW, Australia., Cottrell CE; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.; Department of Pathology, The Ohio State University College of Medicine, Columbus, OH, USA., Mardis ER; The Steve and Cindy Rasmussen Institute for Genomic Medicine, Nationwide Children's Hospital, Columbus, OH, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, OH, USA.; Department of Neurosurgery, The Ohio State University College of Medicine, Columbus, OH, USA., Marshall GM; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Tyrrell V; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia., Haber M; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia., Ziegler DS; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Vittorio O; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia., Trapani JA; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Cowley MJ; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia., Neeson PJ; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia., Ekert PG; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW, Kensington, NSW, Australia. pekert@ccia.org.au.; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Kensington, NSW, Australia. pekert@ccia.org.au.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia. pekert@ccia.org.au.; Cancer Immunology Program, Peter MacCallum Cancer Centre, Parkville, VIC, Australia. pekert@ccia.org.au.; The Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, VIC, Australia. pekert@ccia.org.au.

Publikováno v: Genome medicine [Genome Med] 2023 Apr 03; Vol. 15 (1), pp. 20. Date of Electronic Publication: 2023 Apr 03.

In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer.

Autor: Lau LMS; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Mayoh C; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Xie J; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Barahona P; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., MacKenzie KL; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Wong M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Kamili A; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Tsoli M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Failes TW; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Kumar A; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; Children's Cancer Centre, Royal Children's Hospital, Parkville, Vic., Australia., Mould EVA; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Gifford A; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Chow SO; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Pinese M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Fletcher JI; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Arndt GM; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; ACRF Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Khuong-Quang DA; Children's Cancer Centre, Royal Children's Hospital, Parkville, Vic., Australia.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Vic., Australia., Wadham C; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Batey D; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Eden G; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Trebilcock P; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Joshi S; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Alfred S; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Gopalakrishnan A; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Khan A; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Grebert Wade D; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Strong PA; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Manouvrier E; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Morgan LT; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Span M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Lim JY; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Cadiz R; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Ung C; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Thomas DM; Kinghorn Cancer Centre, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.; Faculty of Medicine, St Vincent's Clinical School, UNSW Sydney, Kensington, NSW, Australia., Tucker KM; Hereditary Cancer Centre, Prince of Wales Hospital, Randwick, NSW, Australia.; Prince of Wales Hospital Clinical School, UNSW Sydney, Randwick, NSW, Australia., Warby M; Hereditary Cancer Centre, Prince of Wales Hospital, Randwick, NSW, Australia., McCowage GB; Cancer Centre for Children, The Children's Hospital at Westmead, Westmead, NSW, Australia., Dalla-Pozza L; Cancer Centre for Children, The Children's Hospital at Westmead, Westmead, NSW, Australia., Byrne JA; Children's Cancer Research Unit, Kids Research, Westmead, NSW, Australia.; Faculty of Medicine and Health, The University of Sydney, NSW, Australia., Saletta F; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Fellowes A; Peter MacCallum Cancer Centre, Melbourne, Vic., Australia., Fox SB; Peter MacCallum Cancer Centre, Melbourne, Vic., Australia.; Department of Medical Oncology, University of Melbourne, Melbourne, Vic., Australia., Norris MD; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; University of New South Wales Centre for Childhood Cancer Research, UNSW Sydney, Kensington, Vic., Australia., Tyrrell V; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Trahair TN; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Lock RB; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Cowley MJ; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Ekert PG; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Peter MacCallum Cancer Centre, Melbourne, Vic., Australia., Haber M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Ziegler DS; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Marshall GM; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia.

Publikováno v: EMBO molecular medicine [EMBO Mol Med] 2022 Apr 07; Vol. 14 (4), pp. e14608. Date of Electronic Publication: 2021 Dec 20.

Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.

Autor: Wong M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Mayoh C; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Lau LMS; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Khuong-Quang DA; Children's Cancer Centre, Royal Children's Hospital, Parkville, VIC, Australia.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia., Pinese M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Kumar A; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Barahona P; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Wilkie EE; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Sullivan P; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Bowen-James R; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Syed M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Martincorena I; Wellcome Trust Sanger Institute, Hinxton, UK., Abascal F; Wellcome Trust Sanger Institute, Hinxton, UK., Sherstyuk A; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Bolanos NA; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Baber J; Hartwig Medical Foundation, Amsterdam, The Netherlands.; Hartwig Medical Foundation Australia, Sydney, NSW, Australia., Priestley P; Hartwig Medical Foundation, Amsterdam, The Netherlands.; Hartwig Medical Foundation Australia, Sydney, NSW, Australia., Dolman MEM; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Fleuren EDG; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Gauthier ME; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Mould EVA; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Gayevskiy V; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Gifford AJ; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Department of Anatomical Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Grebert-Wade D; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Strong PA; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Manouvrier E; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Warby M; Cancer Centre for Children, The Children's Hospital Westmead, Westmead, NSW, Australia., Thomas DM; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia., Kirk J; Familial Cancer Service, Crown Princess Mary Cancer Centre, Westmead Hospital, Westmead, NSW, Australia.; Sydney Medical School, University of Sydney Centre for Cancer Research, The Westmead Institute for Medical Research, Westmead, NSW, Australia., Tucker K; Hereditary Cancer Centre, Prince of Wales Hospital, Randwick, NSW, Australia.; Prince of Wales Hospital Clinical School, University of New South Wales, Randwick, NSW, Australia., O'Brien T; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Alvaro F; John Hunter Children's Hospital, New Lambton Heights, NSW, Australia., McCowage GB; Cancer Centre for Children, The Children's Hospital Westmead, Westmead, NSW, Australia., Dalla-Pozza L; Cancer Centre for Children, The Children's Hospital Westmead, Westmead, NSW, Australia., Gottardo NG; Department of Paediatric and Adolescent Oncology/Haematology, Perth Children's Hospital, Nedlands, WA, Australia.; Brain Tumour Research Program, Telethon Kids Institute, Nedlands, WA, Australia., Tapp H; Women's and Children's Hospital, Adelaide, SA, Australia., Wood P; Monash Children's Hospital, Melbourne, VIC, Australia., Khaw SL; Children's Cancer Centre, Royal Children's Hospital, Parkville, VIC, Australia.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia., Hansford JR; Children's Cancer Centre, Royal Children's Hospital, Parkville, VIC, Australia., Moore AS; Oncology Service, Oncology Service, Queensland Children's Hospital, Brisbane, QLD, Australia.; Child Health Research Centre, The University of Queensland, Brisbane, QLD, Australia., Norris MD; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; University of New South Wales Centre for Childhood Cancer Research, UNSW Sydney, Kensington, NSW, Australia., Trahair TN; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Lock RB; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Tyrrell V; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia., Haber M; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia., Marshall GM; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia., Ziegler DS; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia. d.ziegler@unsw.edu.au.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia. d.ziegler@unsw.edu.au.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia. d.ziegler@unsw.edu.au., Ekert PG; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia. pekert@ccia.org.au.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia. pekert@ccia.org.au.; Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC, Australia. pekert@ccia.org.au.; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia. pekert@ccia.org.au., Cowley MJ; Children's Cancer Institute, Lowy Cancer Centre, UNSW Sydney, Kensington, NSW, Australia. mcowley@ccia.org.au.; School of Women's and Children's Health, UNSW Sydney, Kensington, NSW, Australia. mcowley@ccia.org.au.; Kinghorn Centre for Clinical Genomics, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia. mcowley@ccia.org.au.

Publikováno v: Nature medicine [Nat Med] 2020 Nov; Vol. 26 (11), pp. 1742-1753. Date of Electronic Publication: 2020 Oct 05.

The rise of rapid implementation: a worked example of solving an existing problem with a new method by combining concept analysis with a systematic integrative review.

Autor: Smith J; Centre for Healthcare Resilience and Implementation Science, Australian Institute for Health Innovation, Macquarie University, Level 6, 75 Talavera Road, North Ryde, NSW, 2109, Australia. jim.smith@mq.edu.au., Rapport F; Centre for Healthcare Resilience and Implementation Science, Australian Institute for Health Innovation, Macquarie University, Level 6, 75 Talavera Road, North Ryde, NSW, 2109, Australia., O'Brien TA; Faculty of Medicine, School of Women's and Children's Health, University of New South Wales, Sydney, NSW, Australia.; Kids Cancer Centre, Sydney Children's Hospital, Randwick, Sydney, Australia., Smith S; Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, UK.; School of Nursing and Midwifery, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA, 6027, Australia.; Perth Children's Hospital, Nedlands, Perth, Australia., Tyrrell VJ; Lowy Cancer Research Centre, Children's Cancer Institute, University of New South Wales, C25/9 High Street, University of New South Wales, Kensington NSW, Sydney, 2750, Australia., Mould EVA; Lowy Cancer Research Centre, Children's Cancer Institute, University of New South Wales, C25/9 High Street, University of New South Wales, Kensington NSW, Sydney, 2750, Australia., Long JC; Centre for Healthcare Resilience and Implementation Science, Australian Institute for Health Innovation, Macquarie University, Level 6, 75 Talavera Road, North Ryde, NSW, 2109, Australia., Gul H; Centre for Healthcare Resilience and Implementation Science, Australian Institute for Health Innovation, Macquarie University, Level 6, 75 Talavera Road, North Ryde, NSW, 2109, Australia., Cullis J; Clinical librarian, Information Access and Advisory Services, Macquarie University Library, Macquarie University, 16 Macquarie Walk, North Ryde, NSW, 2109, Australia., Braithwaite J; Centre for Healthcare Resilience and Implementation Science, Australian Institute for Health Innovation, Macquarie University, Level 6, 75 Talavera Road, North Ryde, NSW, 2109, Australia.

Publikováno v: BMC health services research [BMC Health Serv Res] 2020 May 21; Vol. 20 (1), pp. 449. Date of Electronic Publication: 2020 May 21.