Výsledky vyhledávání - "Motzkus, Dirk."

Akademický článek

A genome-wide survey for prion-regulated miRNAs associated with cholesterol homeostasis

Autor: Montag Judith, Brameier Markus, Schmädicke Ann-Christin, Gilch Sabine, Schätzl Hermann M, Motzkus Dirk

Publikováno v: BMC Genomics, Vol 13, Iss 1, p 486 (2012)

Abstract Background Prion diseases are neurodegenerative diseases that are characterized by the conversion of the cellular prion protein (PrPc) into a pathogenic isoform (PrPSc). It is known that neurodegeneration is often accompanied by the disturba

Externí odkaz: https://doaj.org/article/b888932b3c734027b9f5191f6ec03c81

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Akademický článek

Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys

Autor: Stahl-Hennig Christiane, Motzkus Dirk, Sauermann Ulrike, Mußil Bianka, Sopper Sieghart

Publikováno v: Retrovirology, Vol 8, Iss 1, p 77 (2011)

Abstract Background The cytidine deaminases APOBEC3G (A3G) and APOBEC3F (A3F) are innate cellular factors that inhibit replication of a number of viruses, including HIV-1. Since antiviral activity of APOBEC3 has been mainly confirmed by in vitro data

Externí odkaz: https://doaj.org/article/d224f5586890437ca0b930c4e68d10f6

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Akademický článek

Bovine spongiform encephalopathy infection alters endogenous retrovirus expression in distinct brain regions of cynomolgus macaques (Macaca fascicularis)

Autor: Montag Judith, Schmädicke Ann-Christin, Vincendeau Michelle, Greenwood Alex D, Seifarth Wolfgang, Motzkus Dirk

Publikováno v: Molecular Neurodegeneration, Vol 6, Iss 1, p 44 (2011)

Abstract Background Prion diseases such as bovine spongiform encephalopathies (BSE) are transmissible neurodegenerative diseases which are presumably caused by an infectious conformational isoform of the cellular prion protein. Previous work has prov

Externí odkaz: https://doaj.org/article/509f0fb111104e0c9b5ac0133510fbc1

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Akademický článek

Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

Autor: Hunsmann Gerhard, Schulz-Schaeffer Walter J, Opitz Lennart, Hitt Reiner, Montag Judith, Motzkus Dirk

Publikováno v: Molecular Neurodegeneration, Vol 4, Iss 1, p 36 (2009)

Abstract The aim of our study was to analyze the differential expression of miRNAs in the brains of BSE-infected cynomolgus macaques as a model for Creutzfeldt-Jakob disease (CJD). MicroRNAs (miRNAs) are small noncoding RNAs regulating gene expressio

Externí odkaz: https://doaj.org/article/c224f0fa5ce640e3a4dc7132a4da9e67

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