Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Motunrayo Kolawole"'
Autor:
Li Guo, Shancy Jacob, Bhanu Kanth Manne, E. Motunrayo Kolawole, Siqi Guo, Xiang Wang, Darian Murray, Emilia A. Tugolukova, Irina Portier, Yasuhiro Kosaka, Cindy Barba, Matthew T. Rondina, Brian Evavold, Celeste Morley, Seema Bhatlekar, Paul F. Bray
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/14029ee60bef4e05b8286f1d78fd4155
Autor:
Anna Sanecka, Nagisa Yoshida, Elizabeth Motunrayo Kolawole, Harshil Patel, Brian D. Evavold, Eva-Maria Frickel
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
T cell receptor–major histocompatibility complex (TCR–MHC) affinities span a wide range in a polyclonal T cell response, yet it is undefined how affinity shapes long-term properties of CD8 T cells during chronic infection with persistent antigen.
Externí odkaz:
https://doaj.org/article/df6b750c72a44d789dfeb87e59c65db2
Autor:
Brian D. Evavold, Elizabeth Motunrayo Kolawole, Marc K. Jenkins, Dmitri I. Kotov, Deepali Malhotra, Thamotharampillai Dileepan, Peter D. Krueger
Publikováno v:
Nature Biotechnology. 39:943-948
The ability to identify T cells that recognize specific peptide antigens bound to major histocompatibility complex (MHC) molecules has enabled enumeration and molecular characterization of the lymphocytes responsible for cell-mediated immunity. Fluor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1d8c3f58d1f24bf95786dc14c734b5b
https://doi.org/10.1038/s41587-021-00893-9
https://doi.org/10.1038/s41587-021-00893-9
Autor:
Jesus A. Alonso, Jiaqi Ma, Brian D. Evavold, Scott D. Anderson, Elizabeth Motunrayo Kolawole, Lance M. Hellman, Aaron M. Rosenberg, Daniel T. Harris, Brian M. Baker, David M. Kranz, Nishant K. Singh
Publikováno v:
Biochemistry
T cell receptors (TCRs) orchestrate cellular immunity by recognizing peptides presented by a range of major histocompatibility complex (MHC) proteins. Naturally occurring TCRs bind the composite peptide/MHC surface, recognizing peptides that are stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ac2b1aedfe3ff52e2968dbcd4f5bf9
https://doi.org/10.1021/acs.biochem.0c00689
https://doi.org/10.1021/acs.biochem.0c00689
A Critical Insulin TCR Contact Residue Selects High-Affinity and Pathogenic Insulin-Specific T Cells
Autor:
Marissa A. Scavuzzo, Baoyu Liu, Elizabeth Motunrayo Kolawole, Matthew L. Bettini, Maria Bettini, Brian D. Evavold, Lin Guo, Malgorzata Borowiak
Publikováno v:
Diabetes
Type 1 diabetes is an autoimmune-mediated disease that culminates in the targeted destruction of insulin-producing β-cells. CD4 responses in NOD mice are dominated by insulin epitope B:9-23 (InsB9-23) specificity, and mutation of the key T-cell rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c7129600f16d37f30437f003c34163f
https://doi.org/10.2337/db19-0821
https://doi.org/10.2337/db19-0821
Autor:
Derek M Woodruff, Elizabeth Motunrayo Kolawole, Baoyu Liu, Brian D. Evavold, Jennifer D. Hood, Dario A. A. Vignali, Maria Bettini
Publikováno v:
Diabetes
β-Cell antigen recognition by autoreactive T cells is essential in type 1 diabetes (T1D) pathogenesis. Recently, insulin hybrid peptides (HIPs) were identified as strong agonists for CD4 diabetogenic T cells. Here, using BDC2.5 transgenic and NOD mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f34c9b76aff1e5ca2e4b30a119c2bfc
https://doi.org/10.2337/db19-0399
https://doi.org/10.2337/db19-0399
Publikováno v:
Annual review of cell and developmental biology. 37
T cell activation is a critical event in the adaptive immune response, indispensable for cell-mediated and humoral immunity as well as for immune regulation. Recent years have witnessed an emerging trend emphasizing the essential role that physical f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbcd429935cfa86dc06a005ffb9166d8
https://pubmed.ncbi.nlm.nih.gov/34213954
https://pubmed.ncbi.nlm.nih.gov/34213954
Autor:
Heather L. Caslin, Tamara T. Haque, Neha Pondicherry, Marcela T. Taruselli, Andrew J. Spence, Jordan M. Dailey, Kaitlyn Jackson, Amina Abdul Qayum, Sydney A. Kee, David B. Straus, Jason R. Burchett, John J. Ryan, Gregorio Gomez, Elizabeth Motunrayo Kolawole, Brian O. Barnstein, Daniel Abebayehu
Publikováno v:
Cell Immunol
Statins are HMG-CoA reductase inhibitors prescribed for lowering cholesterol. They can also inhibit inflammatory responses by suppressing isoprenylation of small G proteins. Consistent with this, we previously found that fluvastatin suppresses IgE-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::308a25df94cee1b4124fe1827b0efc8e
https://pubmed.ncbi.nlm.nih.gov/34883342
https://pubmed.ncbi.nlm.nih.gov/34883342
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7969, p 7969 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
T cells are critical for a functioning adaptive immune response and a strong correlation exists between T cell responses and T cell receptor (TCR): peptide-loaded MHC (pMHC) binding. Studies that utilize pMHC tetramer, multimers, and assays of three-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21b4ac3283c5989b8aa713fdd1cc8772
https://www.mdpi.com/1422-0067/21/21/7969
https://www.mdpi.com/1422-0067/21/21/7969
Autor:
Sachith D. Gunasinghe, Lukasz Wojciech, C. Farenc, Jasmine Li, Christopher Szeto, Xavier Y.X. Sng, Nicole L. La Gruta, Jamie Rossjohn, Claerwen M. Jones, Katharina Gaus, Stephanie Gras, Angela Nguyen, Jan Petersen, Chantelle Blyth, Pirooz Zareie, Brian D. Evavold, Nicholas R. J. Gascoigne, Jesica R. Jacobs, Alex J. Fulcher, Elizabeth Motunrayo Kolawole, Qianru Wei
Publikováno v:
Science (New York, N.Y.). 372(6546)
Making sense of TCR–pMHC topology Most T cells use a T cell receptor (TCR) that recognizes major histocompatibility complex molecules bound to peptides (pMHCs) derived from both self- and foreign antigens. Although there is great variability in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91ac6459b64053289bc1022d8ac8b27
https://pubmed.ncbi.nlm.nih.gov/34083474
https://pubmed.ncbi.nlm.nih.gov/34083474