Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Mottet, NK"'
Publikováno v:
Acta Pharmacologica et Toxicologica. 58:219-224
Oxygen consumption and percent motile spermatozoa were determined for semen samples from healthy male monkeys Macaca fascicularis. Methyl mercury was added to the samples, in the oxygen measurement chamber, at a concentration of 9 p.p.m. for 15 min.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdb0236d590259b238571ca61897d90
https://doi.org/10.1111/j.1600-0773.1986.tb00097.x
https://doi.org/10.1111/j.1600-0773.1986.tb00097.x
Publikováno v:
Teratology. 34:89-95
Developing rat cerebellums were examined following continuous methylmercury exposure via maternal drinking water at 12.5 ppm during gestation and the suckling period. The continuous exposure resulted in reductions of the total cerebellar cell populat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba86ac00bf9d1ae41a025c6f53bceae9
https://doi.org/10.1002/tera.1420340112
https://doi.org/10.1002/tera.1420340112
Autor:
Mottet Nk, Scribner Jd
Publikováno v:
Carcinogenesis. 2:1235-1239
2-Acetamidophenanthrene (AAP) yields adducts to rat liver DNA and RNA in amounts comparable to those found for the potent hepatocarcinogen 2-acetamidofluorene, but is not hepatocarcinogenic. This suggested that AAP might initiate liver tumors, but wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d62e37bb38562380849787184c13ee
https://doi.org/10.1093/carcin/2.12.1235
https://doi.org/10.1093/carcin/2.12.1235
Autor:
R E Morrissey, Mottet Nk
Publikováno v:
Teratology. 28:399-411
Early tissue damage following a teratogenic dose of arsenic to the dam was studied in mice with the objective of detecting the primary lesion associated with the development of exencephaly. Animals were killed 6 to 21 h after a single 45 mg/kg intrap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b049ce67cfe8b15908c5465a01acbd8c
https://doi.org/10.1002/tera.1420280311
https://doi.org/10.1002/tera.1420280311
Publikováno v:
Pharmacology & Toxicology. 65:223-230
The disposition parameters derived from a compartmental model kinetic analysis of blood Hg levels in nonpregnant, adult female Macaca fascicularis given daily doses of MeHg did not vary with either dosage level (50, 70 or 90 micrograms MeHg/kg b.wt.d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31562e05419ec69fb20398ff4485460c
https://doi.org/10.1111/j.1600-0773.1989.tb01161.x
https://doi.org/10.1111/j.1600-0773.1989.tb01161.x
Publikováno v:
Pharmacology & Toxicology. 60:29-36
These studies were performed to investigate the effects of MeHg on testicular function in Macaca fascicularis monkeys. In an in vivo study involving oral treatment of adult males Macaca fascicularis monkeys with MeHg for 20 weeks, changes in spermato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3b03339a00c879ba0317d024a90de07
https://doi.org/10.1111/j.1600-0773.1987.tb01715.x
https://doi.org/10.1111/j.1600-0773.1987.tb01715.x
Autor:
Mottet Nk
Publikováno v:
Teratology. 10(2)
Near-term fetal rats were examined for possible pathological changes produced by multiple low-dose subcutaneous injections of methylmercury hydroxide during pregnancy. The near-term maternal liver content of mercury served as an index of body content
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b24a38b5c4fb20e7c3b0a78671c6c6c
https://pubmed.ncbi.nlm.nih.gov/4428426
https://pubmed.ncbi.nlm.nih.gov/4428426
Publikováno v:
Pharmacologytoxicology. 64(2)
We have studied the localization and affinity of methyl mercury hydroxide (MeHg) binding sites on microtubules. There is one class of binding sites for MeHg on tubulin, a high affinity class with fifteen sites. MeHg binds to tubulin stoichiometricall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bf42d49013c58ff6c216487a0e951be
https://pubmed.ncbi.nlm.nih.gov/2755920
https://pubmed.ncbi.nlm.nih.gov/2755920
Publikováno v:
Journal of toxicology and environmental health. 12(2-3)
This study was designed to correlated autopsy findings with the effects on cage behavior, laboratory values, and mercury clearance of long-term, low-dose exposure of primates to methylmercury. Six rhesus monkeys were given daily methylmercury hydroxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0aa169e67e60292bd0ed78d71b63b2ce
https://pubmed.ncbi.nlm.nih.gov/6655743
https://pubmed.ncbi.nlm.nih.gov/6655743
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