Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Mott, BT"'
Autor:
Renslo, Adam, Mott, BT, Eastman, RT, Guha, R, Sherlach, KS, Siriwardana, A, Shinn, P, McKnight, C, Michael, S, Lacerda-Queiroz, N, Patel, PR
Publikováno v:
Renslo, Adam; Mott, BT; Eastman, RT; Guha, R; Sherlach, KS; Siriwardana, A; et al.(2015). High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/7n35n5dh
Drug resistance in Plasmodium parasites is a constant threat. Novel therapeutics, especially new drug combinations, must be identified at a faster rate. In response to the urgent need for new antimalarial drug combinations we screened a large collect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::67447c75c1c96e3b5e0f6af73a19a69c
http://www.escholarship.org/uc/item/7n35n5dh
http://www.escholarship.org/uc/item/7n35n5dh
Akademický článek
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Autor:
Jessica Marinello, Craig J. Thomas, Christophe Marchand, Yves Pommier, Anjali Bain, Bryan T. Mott
HIV-1 integrase (IN) is the molecular target of the newly approved anti-AIDS drug raltegravir (MK-0518, Isentress) while elvitegravir (GS-9137, JTK-303) is in clinical trials. The aims of the present study were (1) to investigate and compare the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4664fadfbe3f370874a4155f507776
http://hdl.handle.net/11585/163844
http://hdl.handle.net/11585/163844
Autor:
Kagan AB; Department of Medicine, Division of Clinical Pharmacology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.; Department of Oncology, School of Medicine, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 1M52, Baltimore, MD, 21231-1000, USA., Moses BS; Departments of Pediatrics and Physiology, School of Medicine, Center for Stem Cell Biology and Regenerative Medicine, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, BRB14-021, 655 W Baltimore St, Baltimore, MD, 21201, USA.; Keros Therapeutics, Inc., Lexington, MA, USA., Lapidus R; Department of Medicine, School of Medicine, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA., Mott BT; Department of Neurosurgery, Wake Forest Baptist Health, Winston-Salem, NC, USA., Rai G; Department of Pre-clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA., Anders NM; Department of Oncology, School of Medicine, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 1M52, Baltimore, MD, 21231-1000, USA.; Takeda Pharmaceutical Company, San Diego, CA, USA., Hoag SW; School of Pharmacy, University of Maryland, Baltimore, MD, USA., Rudek MA; Department of Medicine, Division of Clinical Pharmacology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. mrudek2@jhmi.edu.; Department of Oncology, School of Medicine, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 1M52, Baltimore, MD, 21231-1000, USA. mrudek2@jhmi.edu., Civin CI; Departments of Pediatrics and Physiology, School of Medicine, Center for Stem Cell Biology and Regenerative Medicine, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, BRB14-021, 655 W Baltimore St, Baltimore, MD, 21201, USA. Ccivin@som.umaryland.edu.
Publikováno v:
Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2023 Jul; Vol. 92 (1), pp. 39-50. Date of Electronic Publication: 2023 May 30.
Autor:
Ruhl AP; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.; Pulmonary Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland., Jeffries N; Office of Biostatistics Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland., Yang Y; Division of Blood Diseases and Resources, National Heart, Lung, and Blood Institute, Rockville, Maryland., Brooks SD; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland., Naik RP; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Pecker LH; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Mott BT; Wake Forest University School of Medicine, Winston-Salem, North Carolina., Winkler CA; Basic Research Laboratory, National Cancer Institute, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Armstrong ND; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama., Zakai NA; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont., Gutierrez OM; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama., Judd SE; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama., Howard VJ; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama., Howard G; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama.; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont., Ackerman HC; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Publikováno v:
MedRxiv : the preprint server for health sciences [medRxiv] 2023 May 22. Date of Electronic Publication: 2023 May 22.
Autor:
Ruhl AP; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.; Pulmonary Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America., Jeffries N; Office of Biostatistics Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland, United States of America., Yang Y; Division of Blood Diseases and Resources, National Heart, Lung, and Blood Institute, Rockville, Maryland, United States of America., Gutierrez OM; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Muntner P; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Naik RP; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Pecker LH; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America., Mott BT; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, United States of America., Zakai NA; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America., Safford MM; Department of Medicine, Weill Cornell Medicine, New York, New York, United States of America., Lange LA; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado, Denver, Colorado, United States of America., Winkler CA; Basic Research Laboratory, National Cancer Institute, Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont, United States of America., Ackerman HC; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America.
Publikováno v:
PloS one [PLoS One] 2022 Jul 14; Vol. 17 (7), pp. e0271031. Date of Electronic Publication: 2022 Jul 14 (Print Publication: 2022).
Autor:
Bernstock JD; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. jbernstock@partners.org., Kang KD; Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA., Klinger NV; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Olsen HE; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Gary S; Medical Scientist Training Program, University of Alabama at Birmingham, Birmingham, AL, USA., Totsch SK; Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA., Ghajar-Rahimi G; Medical Scientist Training Program, University of Alabama at Birmingham, Birmingham, AL, USA., Segar D; Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA., Thompson EM; Department of Neurosurgery, Duke University, Durham, NC, USA., Darley-Usmar V; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Mott BT; Department of Neurosurgery, Wake Forest Baptist Medical Center, Winston-Salem, NC, USA., Peruzzotti-Jametti L; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK., Friedman GK; Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL, USA. gfriedman@peds.uab.edu.
Publikováno v:
Oncogene [Oncogene] 2022 May; Vol. 41 (19), pp. 2663-2671. Date of Electronic Publication: 2022 Apr 16.
Autor:
Kagan AB; Department of Medicine, Division of Clinical Pharmacology, School of Medicine, Johns Hopkins University, Baltimore, MD, United States., Moses BS; Center for Stem Cell Biology & Regenerative Medicine, Marlene and Stewart Greenebaum Comprehensive Cancer Center, Departments of Pediatrics and Physiology, School of Medicine, University of Maryland, Baltimore, MD, United States., Mott BT; Department of Neurosurgery, Wake Forest Baptist Health, Winston-Salem, NC, United States., Rai G; Department of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, United States., Anders NM; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, United States., Rudek MA; Department of Medicine, Division of Clinical Pharmacology, School of Medicine, Johns Hopkins University, Baltimore, MD, United States.; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, United States., Civin CI; Center for Stem Cell Biology & Regenerative Medicine, Marlene and Stewart Greenebaum Comprehensive Cancer Center, Departments of Pediatrics and Physiology, School of Medicine, University of Maryland, Baltimore, MD, United States.
Publikováno v:
Frontiers in oncology [Front Oncol] 2022 Jan 11; Vol. 11, pp. 790037. Date of Electronic Publication: 2022 Jan 11 (Print Publication: 2021).
Autor:
Ruhl AP; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.; Pulmonary Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland., Jeffries N; Office of Biostatistics Research, National Heart, Lung, and Blood Institute, Bethesda, Maryland., Yang Y; Division of Blood Diseases and Resources, National Heart, Lung, and Blood Institute, Rockville, Maryland., Naik RP; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Patki A; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama., Pecker LH; Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland., Mott BT; University of Alabama at Birmingham School of Medicine, Birmingham, Alabama., Zakai NA; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont., Winkler CA; Basic Research Program, National Cancer Institute, Frederick National Laboratory for Cancer Research, Frederick, Maryland., Kopp JB; Kidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland., Lange LA; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado, Denver, Colorado., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, Alabama., Gutierrez OM; Department of Epidemiology, University of Alabama at Birmingham School of Public Health, Birmingham, Alabama.; Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama., Cushman M; Department of Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont.; Department of Pathology & Laboratory Medicine, Larner College of Medicine at the University of Vermont, Burlington, Vermont., Ackerman HC; Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
Publikováno v:
Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2022 Jan; Vol. 33 (1), pp. 213-224. Date of Electronic Publication: 2021 Oct 27.
Autor:
Christov PP; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States., Kim K; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States., Jana S; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States., Romaine IM; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States., Rai G; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Mott BT; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Allweil AA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States., Lamers A; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States., Brimacombe KR; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Urban DJ; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Lee TD; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Hu X; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Lukacs CM; Beryllium Discovery Corp, 7869 Day Rd West, Bainbridge Island, WA 98110, United States., Davies DR; Beryllium Discovery Corp, 7869 Day Rd West, Bainbridge Island, WA 98110, United States., Jadhav A; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Green N; Beryllium Discovery Corp, 7869 Day Rd West, Bainbridge Island, WA 98110, United States., Moore WJ; NExT Program Support, Applied/Developmental Research Directorate, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States., Stott GM; NExT Program Support, Applied/Developmental Research Directorate, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States., Flint AJ; NExT Program Support, Applied/Developmental Research Directorate, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD 21702, United States., Maloney DJ; National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States., Sulikowski GA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States., Waterson AG; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, United States. Electronic address: a.waterson@vanderbilt.edu.
Publikováno v:
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2021 Jun 01; Vol. 41, pp. 127974. Date of Electronic Publication: 2021 Mar 24.