Persistence and risk factors of occult hepatitis B virus infections among antiretroviral therapy-naïve people living with HIV in Botswana

Autor: Motswedi Anderson, Bonolo B. Phinius, Basetsana K. Phakedi, Mbatshi Mudanga, Lynnette N. Bhebhe, Girlie N. Tlhabano, Patience Motshosi, Tsholofelo Ratsoma, Kabo Baruti, Gorata Mpebe, Wonderful T. Choga, Richard Marlink, Dieter Glebe, Jason T. Blackard, Sikhulile Moyo, Anna Kramvis, Simani Gaseitsiwe

Publikováno v: Frontiers in Microbiology, Vol 15 (2024)

AimThis study aimed to determine the kinetics of occult hepatitis B virus infections (OBI) among people with HIV (PWH).MethodsThe study used archived plasma samples from longitudinal HIV natural history studies. We identified new OBI cases and assess

Externí odkaz: https://doaj.org/article/a1fb6e1bfe774ca3bcb77efb42001557

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Emergence of Omicron FN.1 a descendent of BQ.1.1 in Botswana.

Autor: Choga WT; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.; Faculty of Health Sciences, School of Allied Health Sciences, Gaborone, Private Bag UB 0022, Botswana.; Centre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch 7600, South Africa., Gustani-Buss E; Laboratory for Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium., Tegally H; Centre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch 7600, South Africa., Maruapula D; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana., Yu X; Institute of Evolutionary Biology, University of Edinburgh, Edinburgh EH9 3FL, Scotland, UK., Moir M; Centre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch 7600, South Africa., Zuze BJL; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.; Faculty of Health Sciences, School of Allied Health Sciences, Gaborone, Private Bag UB 0022, Botswana., James SE; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory. Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4001, South Africa., Ndlovu NS; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana., Seru K; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana., Motshosi P; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana., Blenkinsop A; Department of Mathematics, Imperial College London, London, Westminster, SW7 2AZ, United Kingdom., Gobe I; Faculty of Health Sciences, School of Allied Health Sciences, Gaborone, Private Bag UB 0022, Botswana., Baxter C; Centre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch 7600, South Africa., Manasa J; Faculty of Medicine and Health Sciences, Molecular Diagnostics and Investigative Sciences, University of Zimbabwe, Harare, P.O.Box MP167, Zimbabwe., Lockman S; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United States.; Division of Infectious Diseases, Brigham & Women's Hospital, Boston, MA 02115, United States.; Harvard Medical School, Boston, MA, 02115, United States., Shapiro R; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United States., Makhema J; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United States., Wilkinson E; Centre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch 7600, South Africa., Blackard JT; University of Cincinnati College of Medicine, Cincinnati, OH 45267, United States., Lemey P; Laboratory for Clinical and Epidemiological Virology, Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven 3000, Belgium., Lessells RJ; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory. Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4001, South Africa., Martin DP; Division of Computational Biology, Department of Integrative Biomedial Sciences, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town 7925, South Africa., de Oliveira T; Centre for Epidemic Response and Innovation (CERI), School of Data Science and Computational Thinking, Stellenbosch University, Stellenbosch 7600, South Africa.; KwaZulu-Natal Research Innovation and Sequencing Platform (KRISP), School of Laboratory. Medicine and Medical Sciences, University of KwaZulu-Natal, Durban 4001, South Africa.; Department of Global Health, University of Washington, Seattle, WA 98105, United States., Gaseitsiwe S; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United States., Moyo S; Research Laboratory, Botswana Harvard Health Partnership, Gaborone, Private Bag BO 320, Botswana.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, MA 02115, United States.; School of Health Systems and Public Health, University of Pretoria, Pretoria 0002, South Africa.; Division of Medical Virology, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, Cape Town 7602, South Africa.

Publikováno v: Virus evolution [Virus Evol] 2024 Nov 22; Vol. 10 (1), pp. veae095. Date of Electronic Publication: 2024 Nov 22 (Print Publication: 2024).