Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Motoyasu Miura"'
Autor:
Sayuri Kawamoto, Shimako Tanaka, Motoyasu Miura, Yasuharu Kashiwagura, Chiaki Kamiya, Akio Hakamata, Keiichi Odagiri, Naoki Inui, Hiroshi Watanabe, Noriyuki Namiki, Shinya Uchida
Publikováno v:
Chemical and Pharmaceutical Bulletin. 71:441-446
Autor:
Junichi Kawakami, Naoki Inui, Shimako Tanaka, Hiroshi Watanabe, Keiichi Odagiri, Naoki Katayama, Shinya Uchida, Chiaki Kamiya, Motoyasu Miura, Noriyuki Namiki, Akio Hakamata
Publikováno v:
Biologicalpharmaceutical bulletin. 44(6)
A cocktail study is an in vivo evaluation method to assess multiple CYP activities via a single trial and single administration of a cocktail drug that is a combination of multiple CYP substrates. However, multiple blood samples are required to evalu
Autor:
Junichi Kawakami, Shinya Uchida, Hiroshi Watanabe, Noriyuki Namiki, Naoki Inui, Motoyasu Miura, Shimako Tanaka
Publikováno v:
Biologicalpharmaceutical bulletin. 42(9)
There are large inter- and intra-individual variations in CYP3A4 activity. Midazolam, which is predominantly metabolized to 1'-hydroxymidazolam and 4-hydroxymidazolam by CYP3A4, is considered an effective probe for CYP3A4. To determine the area under