Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Motoyasu Honda"'
Autor:
Shoji Furusako, Kumiko Ogawa, Kamon Shirakawa, Motoyasu Honda, Katsuki Naitoh, Yoshitaka Hosaka
Publikováno v:
Platelets. 26(8)
Glycoprotein VI (GPVI) plays a critical role in the platelet response to collagen. Clinical studies suggest that the plasma level of soluble GPVI (sGPVI) is a highly specific and useful platelet activation marker. However, many properties of sGPVI ha
Autor:
Shunji Natsuka, Sumihiro Hase, Yae Ito, Masaaki Naotsuka, Hiroyuki Wakabayashi, Jun-ichi Kajihara, Motoyasu Honda
Publikováno v:
Journal of Biochemistry. 130:543-552
The sugar chains of human urinary thrombomodulin were studied. N- and O-linked sugar chains were simultaneously liberated by hydrazinolysis followed by N-acetylation and were tagged with 2-aminopyridine. Then the structures of the N- and O-linked pyr
Autor:
Hiroyasu Nagase, Kazuhisa Miyamoto, Motoyasu Honda, Supanee Duangteraprecha, Kazumasa Hirata, Tomohiro Akagi, Yayoi Sakamoto
Publikováno v:
Journal of Bioscience and Bioengineering. 87:781-786
A reaction model for the flavin mononucleotide-mediated coupling of catharanthine (C) and vindoline (V) under near-ultraviolet light was established based on the results of experiments on the effects of various physical and chemical factors on the di
Autor:
Tomohiro Akagi, Supanee Duangteraprecha, Hiroshi Katayama, Motoyasu Honda, Kazuhisa Miyamoto, Kazumasa Hirata, Etsuko Morihara, Masuo Nakae
Publikováno v:
Biotechnology Letters. 19:53-57
Vinblastine (VLB) is an antineoplastic agent contained in leaves of Catharanthus roseus. One-pot synthesis of VLB from vindoline and catharanthine, biosynthetic precursors in the plant, was achieved under biomimetic conditions. FMN-mediated coupling
Autor:
Supanee Duangteraprecha, Etsuko Morihara, Kazumasa Hirata, Kazuhisa Miyamoto, Masuo Nakae, Motoyasu Honda, Hiroshi Katayama
Publikováno v:
Journal of Fermentation and Bioengineering. 83:227-232
Non-enzymic coupling of vindoline and catharanthine to synthesize the dihydropyridinium intermediate (DHPI) of dimeric alkaloids was achieved under near-ultraviolet light irradiation with a peak at 370 nm in the presence of flavin mononucleotide (FMN
Autor:
Motoyasu Honda, Chizuko Hattori, Katsuji Tani, Kenji Katoh, Masao Nasu, Taisei Shimaoka, Nobuyasu Yamaguchi
Publikováno v:
Journal of Fermentation and Bioengineering. 84:519-523
The genomic DNA content of a cultured cell of Marchantia polymorpha HYA-2F was examined using a flow cytometer. It was estimated to be 0.32 pg (C), with a G+C content of 57.1%. The DNA content was less than that of Arabidopsis thaliana. The frequency
Autor:
Tetsushi Kawahara, Yukiko Yatagai, Yoshitaka Hosaka, Mikihiko Shinozaki, Motoyasu Honda, Shoji Furusako, Hiroshi Takayama, Kazuyuki Nakayama, Tooru Yokoyama, Tomokazu Matsusue, Michiru Kurihara, Katsuki Naitoh, Jiro Hirose, Kamon Shirakawa
Publikováno v:
The Journal of clinical investigation. 118(5)
Platelet adhesion to vascular subendothelium, mediated in part by interactions between collagen and glycoprotein VI (GPVI) complexed with Fc receptor gamma-chain, is crucial for thrombus formation. Antiplatelet therapy benefits patients with various
Autor:
Shoji Furusako, Yoshitaka Hosaka, Hiroshi Takayama, Motoyasu Honda, Kazuyuki Nakayama, Toru Yamakawa, Tetsushi Kawahara, Mikihiko Shinozaki, Katsuki Naitoh, Kamon Shirakawa
Publikováno v:
Blood. 106:2168-2168
The first reported patient with platelet GPVI deficiency (Blood1987;69:1712) had anti-GPVI antibodies (YA-Abs) in the patient’s serum, which contributed to later progress in identification of GPVI as a novel collagen receptor. Although there is now