Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice

Autor: Hossain, ASM Sakhawat, Clarin, Maria Thea Rane Dela Cruz, Kimura, Kenichi, Biggin, George, Taga, Yuki, Uto, Koichiro, Yamagishi, Ayana, Motoyama, Eri, Narenmandula, Mizuno, Kazunori, Nakamura, Chikashi, Asano, Keiichi, Ohtsuki, Sumio, Nakamura, Tomoyuki, Kanki, Sachiko, Baldock, Clair, Raja, Erna, Yanagisawa, Hiromi

Publikováno v: In Matrix Biology February 2025 135:24-38

Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice.

Autor: Hossain AS; Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan; Department of Pharmacy, Varendra University, Bangladesh., Clarin MTRDC; School of Integrative and Global Major, University of Tsukuba, Japan; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan; National Institute for Material Science, Japan., Kimura K; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan., Biggin G; Wellcome Trust Centre for Cell-Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, UK., Taga Y; Nippi Research Institute of Biomatrix, Japan., Uto K; National Institute for Material Science, Japan., Yamagishi A; National Institute of Advanced Industrial Science and Technology, Japan., Motoyama E; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan., Narenmandula; Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan., Mizuno K; Nippi Research Institute of Biomatrix, Japan., Nakamura C; National Institute of Advanced Industrial Science and Technology, Japan., Asano K; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan., Ohtsuki S; Department of Pharmaceutical Microbiology, Faculty of Life Sciences, Kumamoto University, Japan., Nakamura T; Department of Pharmacology, Kansai Medical University, Japan., Kanki S; Department of Surgery, Osaka Medical and Pharmaceutical University, Japan., Baldock C; Wellcome Trust Centre for Cell-Matrix Research, Division of Cell Matrix Biology and Regenerative Medicine, Faculty of Biology, Medicine and Health, University of Manchester, UK., Raja E; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan. Electronic address: rajaerna@tara.tsukuba.ac.jp., Yanagisawa H; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan. Electronic address: hkyanagisawa@tara.tsukuba.ac.jp.

Publikováno v: Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2024 Nov 28. Date of Electronic Publication: 2024 Nov 28.