Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mototaka Sugiura"'
Autor:
Gene Kurosawa1 gene@fujita-hu.ac.jp, Mototaka Sugiura2 msugiura@fujita-hu.ac.jp, Yoshinobu Hattori3,4 y-hattori@daidohp.or.jp, Hiroyuki Tsuda5 htsuda@phar.nagoya-cu.ac.jp, Yoshikazu Kurosawa1 kurosawa@fujita-hu.ac.jp
Publikováno v:
International Journal of Molecular Sciences. Nov2016, Vol. 17 Issue 11, p1862. 8p. 1 Diagram, 1 Chart.
Autor:
Keiko Majima, Yoshitaka Iba, Daisuke Hirano, Ritsuko Kubota-Koketsu, Yoshinobu Okuno, Ayami Yamasaki, Yoshikazu Kurosawa, Nobuko Ohshima, Mototaka Sugiura, Shunji Yoshida, Yoshizo Asano, Gene Kurosawa
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7422, p 7422 (2020)
Volume 21
Issue 19
International Journal of Molecular Sciences, Vol 21, Iss 7422, p 7422 (2020)
Four kinds of avian-derived H5N1 influenza virus, A/Vietnam/1194/2004 (Clade 1), A/Indonesia/5/2005 (Clade 2.1), A/Qinghai/1A/2005 (Clade 2.2), and A/Anhui/1/2005 (Clade 2.3), have been stocked in Japan for use as pre-pandemic vaccines. When a pandem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81125ce9b30d8b5ac056e604a529aeb
Publikováno v:
International Journal of Molecular Sciences, Vol 17, Iss 11, p 1862 (2016)
International Journal of Molecular Sciences; Volume 17; Issue 11; Pages: 1862
International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 17; Issue 11; Pages: 1862
International Journal of Molecular Sciences
In previous studies, we identified 29 tumor-associated antigens (TAAs) and isolated 488 human monoclonal antibodies (mAbs) that specifically bind to one of the 29 TAAs. In the present study, we performed histochemical analysis of 36 freshly resected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd887ceeebd5b2ae079e28078425452b
http://www.mdpi.com/1422-0067/17/11/1862
http://www.mdpi.com/1422-0067/17/11/1862
Autor:
Yoshikazu Kurosawa, Miwa Morita, Mariko Sumitomo, Yasushi Akahori, Kazuhiro Suzuki, Yoshitaka Iba, Gene Kurosawa, Miho Tanaka, Kazuki Matsuda, Atsushi Sugioka, Keiko Eguchi, Mototaka Sugiura, Chiho Muramatsu, Nobuhiro Hayashi, Akihiko Takasaki, Noriko Sato
Publikováno v:
Journal of Immunological Methods. 351:1-12
In order to isolate monoclonal antibodies (mAbs) that bind to tumor-associated antigens (Ags) we developed the following strategy. Using the phage-display Ab library we isolated a large number of mAbs that bind to the surface of human tumor cells. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c170300fee51af18e969560d85b312a2
https://doi.org/10.1016/j.jim.2009.09.003
https://doi.org/10.1016/j.jim.2009.09.003
Autor:
Gene Kurosawa, Mototaka Sugiura, Yasushi Akahori, Chiho Muramatsu, Keiko Eguchi, Kazuhiro Suzuki, Yoshitaka Iba, Miho Tanaka, Atsushi Sugioka, Yoshikazu Kurosawa, Miwa Morita, Mariko Sumitomo
Publikováno v:
Biochemical and Biophysical Research Communications. 378:832-835
We developed a method termed ICOS (isolation of antigen-antibody complexes through organic solvent) for comprehensive isolation of monoclonal antibodies (mAbs) bound to molecules on the cell surface. By mixing a large number of phage particles of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa8ce0f49cfeb508c2ae37e2819705af
https://doi.org/10.1016/j.bbrc.2008.11.129
https://doi.org/10.1016/j.bbrc.2008.11.129
Autor:
Ryoichi Shiroki, Kiyotaka Hoshinaga, Mototaka Sugiura, Chiho Muramatsu, Shuichi Miyakawa, Misaki Ando, Koutarou Maeda, Miho Tanaka-Hashiba, Yoshinori Ukai, Juvy Subere, Yasushi Akahori, Noriko Sato, Keiko Eguchi, Yoshikazu Kurosawa, Ichiro Uyama, Satoko Morigaki, Mai Sugiura, Miwa Morita, Mariko Sumitomo, Atsushi Sugioka, Yoshikazu Mizoguchi, Gene Kurosawa, Yoshinobu Hattori, Akihiko Takasaki, Kazuki Inaba
Publikováno v:
Cancer science. 102(1)
The search for effective antibodies (Ab) for curable cancer immunotherapy has been a quest of many research groups in order to find an effective target that exists on the cancer cell surface. So far there have been no conclusive answers to shed light
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35683e22152dea866f815143b374c6bd
https://pubmed.ncbi.nlm.nih.gov/21040215
https://pubmed.ncbi.nlm.nih.gov/21040215
Autor:
Hiroyuki Tsuda, Keiko Eguchi, Mototaka Sugiura, Chiho Muramatsu, Yoshitaka Iba, Miho Tanaka, Yoshikazu Kurosawa, Yoshinobu Hattori, Mariko Sumitomo, Yuka Kitamura, Gene Kurosawa, Yasushi Akahori
Publikováno v:
Biochemical and biophysical research communications. 383(4)
We reported comprehensive screening for antigens (Ags) overexpressed on various carcinomas via isolation of human monoclonal antibodies (mAbs) that may be therapeutic in a previous paper (Proc. Natl. Acad. Sci. USA 105, 7287-7292, 2008). Twenty-one d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e26c80025da2702ffdde826edc5f0be4
https://pubmed.ncbi.nlm.nih.gov/19371721
https://pubmed.ncbi.nlm.nih.gov/19371721
Autor:
Gene Kurosawa, Kiyotaka Hoshinaga, Nobuhiro Takahashi, Mikihiro Shamoto, Hiroyuki Tsuda, Yoshinobu Hattori, Mototaka Sugiura, Nobuhiro Hayashi, Yoshikazu Mizoguchi, Atsushi Sugioka, Yoshitaka Iba, Yoshinori Ukai, Akihiko Takasaki, Shuichi Miyakawa, Ryoichi Shiroki, Miho Tanaka, Susumu Hamada-Tsutsumi, Mamoru Shiraishi, Sally Fujiyama, Noriko Sato, Kazuhiro Suzuki, Yasushi Akahori, Maiko Kurosawa, Chiho Muramatsu, Kazuki Matsuda, Keiko Eguchi, Yoshikazu Kurosawa, Miwa Morita, Mariko Sumitomo, Ryoichi Kato
Although several murine mAbs that have been humanized became useful therapeutic agents against a few malignancies, therapeutic Abs are not yet available for the majority of the human cancers because of our lack of knowledge of which antigens (Ags) ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4bbd09724bfcba04a2e77677da6772f
https://europepmc.org/articles/PMC2377314/
https://europepmc.org/articles/PMC2377314/
Autor:
Keizo Hirayama, Kazumi Ohya, Nobutaka Tsunakawa, Hiroaki Kubo, Kazuhiro Imai, Zenzo Tamura, Hirotaro Narabayashi, Mototaka Sugiura
Publikováno v:
Chemicalpharmaceutical bulletin. 20(4)
One gram of L-DOPA was administered orally to the patients with Parkinson's disease and normal persons. Plasma DOPA and catecholamines, urinary DOPA, catecholamines and aromatic acids were determined by gas chromatography both before and after acid h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848699224c9d3f4d5366299c804b0472
https://pubmed.ncbi.nlm.nih.gov/5045616
https://pubmed.ncbi.nlm.nih.gov/5045616
Publikováno v:
Chemicalpharmaceutical bulletin. 19(2)
Nanogram order determination of catecholamines in rat tissues and serum was achieved. The recovery of added catecholamines to the acid homogenates was about 50%. The presence of epinephrine in brain was confirmed. The amount of dopamine was unexpecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddd4fa352795c2c11df6c253e994248
https://pubmed.ncbi.nlm.nih.gov/5549061
https://pubmed.ncbi.nlm.nih.gov/5549061